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| 1 | Natural orifice transluminal endoscopic surgeryvs laparoscopic ovariectomy:Complications and inflammatory response显示文摘AIM:To compare natural orifice transluminal endoscopic surgery (NOTES) vs standard laparoscopic ovariectomy in mini pigs with respect to technical aspects,complications and parameters of systemic inflammatory response.METHODS:This was a randomized,experimental,survival study.Ten female mini pigs underwent NOTES transgastric ovariectomy (NOTES group) and ten female mini pigs underwent laparoscopic ovariectomy (LAP group).A 'percutaneous endoscopic gastrostomy' approach with guidewire and sphincterotome was used for gastrotomy creation.The ovary was resected using standard biopsy forceps and a snare.The access site was closed using a 'KING' closure with a single endoloop and several clips.In the laparoscopic group,a three-port laparoscopy and an ovariectomy were performed with the use of standard laparoscopic devices.C-reactive protein (CRP),white blood count and interleukin (IL)-6 plasma levels were used as indicators of systemic inflammatory response.All animals were euthanized 28 d after surgery.RESULTS:All animals survived without complications.The mean procedure time was 41.3 min ± 17.6 min (NOTES group) and 25.7 min ± 5.25 min (LAP group,P < 0.02).Postmortem examinations demonstrated that 50% and 70% of animals were free of any complications in the NOTES and LAP groups,respectively.The remaining animals developed minor complications (adhesions) in a comparable frequency between the two groups.In the NOTES group,one animal developed a small intramural gastric abscess close to the gastrotomy site.A minor serous exudate that was present in 50% and 40% of the animals in the NOTES and laparoscopy groups,respectively,was not considered a complication.In both groups CRP levels increased significantly on the 2nd and 7th postoperative days (POD) and returned to normal after 28 d.On POD 2,an increase of CRP level was significantly higher in the NOTES group compared to the LAP group.Values of IL-6 did not differ from baseline values in either of the groups postoperatively.Interestingly,the platelet count decreased significantly on POD 2,but returned close to baseline values on POD 7 and PODs 28-30.CONCLUSION:Both NOTES and laparoscopic ovariectomies had a similar frequency of minor complications.However,the NOTES technique produced an increased systemic inflammatory response on POD 2. | Jan Martínek Ondej Ryska Tereza Filípková Radek Dolezel Stefan Juhas Jan Motlík Monika Holubová Vladimír Nosek Barbora Rotnáglová Miroslav Zavoral Miroslav Ryska | 2012 | World Journal of Gastroenterology2012，18，27： | 4 |
| 2 | 查看详情显示文摘 | Motl O | | 0，，： | 1 |
| 3 | Effect of exercise training on walk- ing mobility in multiple sclerosis: a meta-analysis 显示文摘 | Snook Motl RW | 2009 | Neurorehabilitation & Neural Repair2009，23，2： | 1 |
| 4 | Influence of Dietary Sodium Level on Utilization of Methionine from DL-Methionine and Liquid Methionine-Hydroxy Analogue显示文摘 | Motl M A Fritts C A Waldroup P W | 2005 | J Appli Poult Res2005，14，： | 1 |
| 5 | Symptoms, self-efficacy, and physical activity among individuals with multiple sclerosis显示文摘 | Motl RW Snook EM McAuley E | 2006 | Res Nurs Health2006，29，： | 1 |
| 6 | Engineering plasmonic metal col- loids through composition and structural design显示文摘 | Motl NE Smith AF Desantis C J | 2014 | Chem Soc Rev2014，43，11： | 1 |
| 7 | Efficacy of a behav- ioral intervention for reducing sedentary behavior in per- sons with multiple sclerosis: a pilot examination 显示文摘 | Klaren RE Hubbard EA Motl RW | 2014 | A- merican Journal of Preventive Medicine2014，47，5： | 1 |
| 8 | Physical activity and quality of life in multiple sclerosis: intermediary roles of disability, fatigue, mood, pain, self-efficacy and social support显示文摘 | Motl RW McAuley E Snook EM | 2009 | Psychol Health Med2009，4，1： | 1 |
| 9 | Symptoms, self - efficacy, and physical aclivity among individuals with multiple sclerosis显示文摘 | Motl RW Snook EM McAuley E | 2006 | Res Nuts Health2006，29，6： | 1 |
| 10 | Flavonoids from Ephedra sinica stapf显示文摘 | Purev O Pospisil F Motl O | 1988 | Collect Czech Chem Commun1988，53，12： | 1 |
| 11 | effects of Exer- cise in experimental autoimmune encephalomyelitis (an animal model of multiple sclerosis) 显示文摘 | Klaren RE Motl RW Woods JA | 2014 | Journal of Neu- roimmunology2014，274，12： | 1 |
| 12 | Naturally occurring changes in physical activity are inversely related to depressive symptoms during early adolescence显示文摘 | Motl RW Birmbaum S Kubik MY | 2004 | Psychosom Med2004，66，3： | 1 |
| 13 | The safety of ex- ercise training in multiple sclerosis: a systematic review 显示文摘 | Pilutti LA Platta ME Motl RW | 2014 | Journal of the Neurological Sciences2014，343，12： | 1 |
| 14 | Factorial validity and invariance of questionnaires measuring social-cognitive determinants of physical activity among adolescent girls显示文摘 | Motl R W Dishman R K Trost S G | 2000 | Preventive Medicine2000，31，5： | 1 |
| 15 | Validation of the multidimensional outcome expectation for exercise scale in am- bulatory, symptom-free persons with multiple sderosis显示文摘 | McAuley E Motl RW White SM | 2010 | Arch Phys Med Rehabil2010，91，1： | 1 |
| 16 | Effects of betaine and chloline on response to methionine supple- mentation to broiler diets formulated to industry stan- dards显示文摘 | WALDROUP P W MOTL M A YAN F | 2006 | Journal of Applied Poultry Research2006，15，： | 1 |
| 17 | Energy cost of walking and its association with gait parameters, daily activity, and fatigue in persons with mild multiple sclerosis 显示文摘 | Motl RW Sandroff BM Suh Y | 2012 | Neurorehabil Neural Repair2012，26，8： | 1 |
| 18 | Progress toward construct validation of the Self-Presentation in Exercise Questionnaire(SPEQ)显示文摘 | Conroy D E Motl R W & Hall E G | 2000 | Journal of Sport and Exercise Psychology2000，22，： | 1 |
| 19 | Progress toward construct validation of the Self-Presentation in Exercise Questionnaire (SPEQ)显示文摘 | Conroy D E Motl R W Hall E G | 2000 | Journal of Sport and Exercise Psychology2000，22，： | 1 |
| 20 | Exercise and mood:a selective review andsynthesis of research employing the Profile of Mood States显示文摘 | Berger BG Motl RW | 2000 | J ApplSport Psychol2000，1，12： | 1 |
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