|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Cadmium-induced neurotoxicity: still much ado显示文摘Cadmium(Cd) is a highly toxic heavy metal that accumulates in living system and as such is currently one of the most important occupational and environmental pollutants. Cd reaches into the environment by anthropogenic mobilization and it is absorbed from tobacco consumption or ingestion of contaminated substances. Its extremely long biological half-life(approximately 20–30 years in humans) and low rate of excretion from the body cause cadmium storage predominantly in soft tissues(primarily, liver and kidneys) with a diversity of toxic effects such as nephrotoxicity, hepatotoxicity, endocrine and reproductive toxicities. Moreover, a Cd-dependent neurotoxicity has been also related to neurodegenerative diseases such as Alzheimer's and Parkinson's diseases, amyotrophic lateral sclerosis, and multiple sclerosis. At the cellular level, Cd affects cell proliferation, differentiation, apoptosis and other cellular activities. Among all these mechanisms, the Cd-dependent interference in DNA repair mechanisms as well as the generation of reactive oxygen species, seem to be the most important causes of its cellular toxicity. Nevertheless, there is still much to find out about its mechanisms of action and ways to reduce health risks. This article gives a brief review of the relevant mechanisms that it would be worth investigating in order to deep inside cadmium toxicity. | Jacopo Junio Valerio Branca Gabriele Morucci Alessandra Pacini | 2018 | Neural Regeneration Research2018，13，11： | 10 |
| 2 | Percutaneous embolization of an isolated hypogastric artery aneurysm:a case report显示文摘 | Battaglia M Morucci R Bartolucci | 1998 | J Cardiovasc Surg1998，39，6： | 1 |
| 3 | Effects of vitamin D-binding protein-derived macrophage-activating factor on human breast cancer cells显示文摘 | Pacini S Punzi T Morucci G | 2012 | Anticancer Res2012，32，： | 1 |
| 4 | Bioelectrical impedance techniques in medicine 显示文摘 | MORUCCI J P VALENTINUZZI M E RIGAUD B | 1996 | Critical Reviews in Biomedical Engineering1996，24，46： | 1 |
| 5 | Percutaneous treantment of pelvic congestion syndrome显示文摘 | Pieri S Agresti P Morucci M | 2003 | Radiol Med(Torino)2003，105，12： | 1 |
| 6 | Bioelectrieal Impedance Techniques in Medicine 显示文摘 | Bernard Rigand Jean-Pierre Morucci | 1996 | Critical Reviews in Biomedical Engineering1996，24，46： | 1 |
| 7 | Percutaneous treatment of pelvic congestion syndrome显示文摘 | Pieri S Agresti P Morucci M | | 0，，1： | 1 |
| 8 | A therapeutic alter- native in the treatment of epididymal cysts:pereutaneous selerotherapy显示文摘 | Pieri S Agresti P Morucci M | 2003 | Radiol Med2003，105，56： | 1 |
| 9 | Percutaneous treantment of pelvic congestion syndrome显示文摘 | Pieri S Agresti P Morucci M | 2003 | Radio1 Med2003，105，12： | 1 |
| 10 | Brachial venous pressure measurement for diagnosis of pulmonary embolism 显示文摘 | Todini AR Pergolini D Morucci M | 2012 | Clin Ter2012，163，5： | 1 |
| 11 | Optional vena cava filters:preliminary experience with a new vena cava filter显示文摘 | Pieri S Agresti P Morucci M | | 0，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员