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| 1 | Human Immunodeficiency Virus Infection-Associated Mortality during Pulmonary Tuberculosis Treatment in Six Provinces of China显示文摘Objective To investigate the risk factors attributable to tuberculosis-related deaths in areas with human immunodeficiency virus(HIV) infection epidemics. Methods A prospective cohort study of newly registered patients in tuberculosis(TB) dispensaries in six representative Chinese provinces was conducted from September 1, 2009 to August 31, 2011. Risk factors for TB-associated death were identified through logistic regression analysis. Results Of 19,103 newly registered pulmonary TB patients, 925(4.8%) were found to be HIV-positive. Miliary TB and acid-fast bacillus smear-negative TB were more common among these patients. Out of a total of 322(1.7%) deaths that occurred during TB treatment, 85(26%) of the patients were co-infected with HIV. Multivariate analysis revealed that HIV infection was the strongest predictor of death [adjusted odds ratio(aO R) 7.86]. Other significant mortality risk factors included presentation with miliary TB(aO R 4.10; 95% confidence interval: 2.14-7.88), ≥35 years of age(aO R 3.04), non-Han ethnicity(aO R 1.67), and farming as an occupation(aO R 1.59). For patients with TB/HIV co-infection, miliary TB was the strongest risk factor for death(aO R 5.48). A low CD4 count(≤ 200 cells/μL)(aO R 3.27) at the time of TB treatment initiation and a lack of antiretroviral therapy(ART) administration(aO R 3.78) were also correlated with an increased risk of death. Conclusion Infection with HIV was independently associated with increased mortality during TB treatment. Offering HIV testing at the time of diagnosis with TB, early TB diagnosis among HIV/acquired immunodeficiency syndrome patients, and the timely provision of ART were identified as the key approaches that could reduce the number of HIV-associated TB deaths. | LAI Yu Ji LIU Er Yong WANG Li Ming Jamie P MORANO WANG Ning Kaveh KHOSHNOOD ZHOU Lin CHENG Shi Ming | 2015 | Biomedical and Environmental Sciences2015，28，6： | 4 |
| 2 | A level set approach to Eulerian-Lagrangiancoupling显示文摘 | Arienti M Hung P Morano E Shepherd J E | 2003 | Journal of Computational Physics2003，185，1： | 1 |
| 3 | Resilience and Coping With Trauma: Does Gender Make a Difference? 显示文摘 | Morano C | 2010 | Journal of Human Behavior in the Social Environment2010，20，4： | 1 |
| 4 | The response to heat shock and oxidative stress in Saccharomyces cerevisiae显示文摘 | Morano KA Grant CM Moye-Rowley WS | 2012 | Genetics2012，190，4： | 1 |
| 5 | The response to heat shock and oxidative stress in saccharomyces cerevisiae显示文摘 | Morano KA Grant CM Moye-Rowley WS | 2012 | Genetics2012，190，4： | 1 |
| 6 | Preflex beams a method of calculation of creep and shrinkage effects 显示文摘 | Morano S G Mannini C | 2006 | Journal of Bridge Engineering2006，11，1： | 1 |
| 7 | Chronic venous insufficiency: assessment with deseending venography 显示文摘 | MORANO J U RAJU S | 1990 | Radiology1990，174，2： | 1 |
| 8 | EIectrophysiological alterations of the central nervous system in diabetes mellitus显示文摘 | Di Mario U Morano S Valle E | 1995 | Diabetes Metab Rev1995，11，3： | 1 |
| 9 | Heat Shock Factor function and regulation in resposeto cellular stress,growth,and differentiation signals显示文摘 | MORANO K A THIELE D J | 1999 | Gene Exp1999，7，： | 1 |
| 10 | New trieks for an old dog: the evolving worl1 of HSP70显示文摘 | Morano KA | 2007 | Ann NY Acad Sci2007，1113，1： | 1 |
| 11 | Percutaneous catheter drainage of post-traumatic urinoma显示文摘 | Morano JU Burkhalter JL | 1985 | J Urol1985，134，： | 1 |
| 12 | Budd-Chiari syndrome as the first manifestation of polycythemia vera in young women with inherited thrombophilie state: an aggressive form of myeloproliferative disorder requiting multidisciplinary management 显示文摘 | Breccia M Morano SG D'Andrea M | 2005 | Eur J Haematol2005，75，5： | 1 |
| 13 | The SOFA(sepsis-related organ failure assessment)score to describe organ dysfunction/failure显示文摘 | Vincent JL Morano R Takala J | 1996 | Intensiv care Med1996，22，10： | 1 |
| 14 | Incidence andplayer risk factors for injury in youth football 显示文摘 | Malina RM Morano PJ Barron M | 2006 | Clin JSport Med2006，16，3： | 1 |
| 15 | A charge selectivity impairment in protein permselectivity is present in type 2 diabetes显示文摘 | Morano S Pietravalle P De Rossi M G | 1993 | Acta Diabetol1993，30，3： | 1 |
| 16 | In vitro and in vivo effects of cefodizime and ceftriaxone on oxygen-dependent killing of neutrophils of elderly patients with exacerbation of chronic bronchitis显示文摘 | Papa L Guida G Morano CM | 1996 | Infez Med1996，4，4： | 1 |
| 17 | Correlation of myosin heavy chain expression in the rat with cAMP in different models of hypertension-induced cardiac hypertrophy显示文摘 | Morano I | 1993 | Mol Cell Cardiol1993，，25： | 1 |
| 18 | Androgen receptor independent cardiovascular action of the antiandrogen flutamide显示文摘 | Radu Iliescu Luciana A. Campos Wolfgang-Peter Schlegel Ingo Morano Ovidiu Baltatu Michael Bader | 2003 | Journal of Molecular Medicine2003，，7： | 1 |
| 19 | Antioxidant treatment associated with sildenafil reduces monocyte activation and markers of endothelial damage in patients with diabetic erectile dysfunction: a double-blind, placebo-controlled study显示文摘 | Morano S Mandosi E Fallarino M | 2007 | Eur Urol2007，52，6： | 1 |
| 20 | New tricks for an old dog:the evolving world of Hsp70 显示文摘 | Morano KA | 2007 | Ann N Y Acad Sci2007，1113，： | 1 |
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