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| 1 | Microstructure and mechanical properties of ZrB 2 –MoSi 2 ceramic composites produced by different sintering techniques显示文摘 | Diletta Sciti Frédéric Monteverde Stefano Guicciardi Giuseppe Pezzotti Alida Bellosi | 2006 | Materials Science & Engineering A2006，，1： | 2 |
| 2 | Evaluation of antibody-dependent cell-mediatedcy totoxicity activity and cetuximab response in KRAS wildtype metastatic colorectal cancer patients显示文摘AIM:To investigate the prognostic role of invariant natural killer T(iNKT) cells and antibody-dependent cell-mediated cytotoxicity(ADCC) in wild type KRAS metastatic colorectal cancer(mC RC) patients treated with cetuximab.METHODS: Forty-one KRAS wt mC RC patients,treated with cetuximab and irinotecan-based chemotherapy in Ⅱ and Ⅲ lines were analyzed. Genotyping of single nucleotide polymorphism(SNP)s in the FCGR2A,FCGR3A and in the 3' untranslated regions of KRAS and mutational analysis for KRAS,BRAF and NRAS genes was determined either by sequencing or allelic discrimination assays. Enriched NK cells were obtained from lymphoprepperipheral blood mononuclear cell and iN KT cells were defined by co-expression of CD3,TCRVα24,TCRVβ11. ADCC was evaluated as ex vivo NK-dependent activity,measuring lactate dehydrogenase release.RESULTS: At basal,mCRC patients performing ADCC activity above the median level(71%) showed an improved overall survival(OS) compared to patients with ADCC below(median 16 vs 8 mo;P=0.026). We did not find any significant correlation of iN KT cells with OS(P=0.19),albeit we observed a trend to a longer survival after 10 mo in patients with iN KT above median basal level(0.382 cells/microliter). Correlation of OS and progression-free survival(PFS) with interesting SNPs involved in ADCC ability revealed not to be significant. Patients carrying alleles both with A in FCGR2 A and TT in FCGR3A presented a trend of longer PFS(median 9 vs 5 mo;P=0.064). Chemotherapy impacted both iN KT cells and ADCC activity. Their prognostic values get lost when we analysed them after 2 and 4 mo of treatment.CONCLUSION: Our results suggest a link between iN KT cells,basal ADCC activity,genotypes in FCGR2A and FCGR3A,and efficacy of cetuximab in KRAS wt mC RC patients. | cristiana lo nigro vincenzo ricci daniela vivenza martino monteverde giuliana strola francesco lucio federica tonissi emanuela miraglio cristina granetto mirella fortunato marco carlo merlano | 2016 | World Journal of Gastrointestinal Oncology2016，8，2： | 2 |
| 3 | Electrical resistivity of the Ti 4 O 7 Magneli phase under high pressure显示文摘 | Acha C Monteverde M Nunez-Regueiro M | 2003 | Eur Phys J B2003，34，： | 1 |
| 4 | Oxidation behavior of titanium cartnitride based materials 显示文摘 | Monteverde F Bellosi A | 2002 | Corros Sci2002，44，9： | 1 |
| 5 | Development and Application of a Fault Tolerance Measure for Serial and Parallel Robotic Structures显示文摘 | Monteverde V Tosunoglu S | | 0，，1： | 1 |
| 6 | Oxidation behavior of titanium carbonitride based materials显示文摘 | Monteverde F Bellosi A | | 0，，09： | 1 |
| 7 | Technical dialog as an ineenlive for vertical integration in the semiconductor industry 显示文摘 | MONTEVERDE K | 1995 | Management Science1995，41，10： | 1 |
| 8 | The thermal stability in air of hot-pressed diboride matrix composites for uses at ultra-high temperatures显示文摘 | MONTEVERDE F | 2005 | Corros Sci2005，47，： | 1 |
| 9 | Efficacy of HfN as sintering aid in the manufacture of ultrahigh-temperature metal diborides-matrix ceramics显示文摘 | Monteverde F Bellosi A | 2004 | J Mater Res2004，19，12： | 1 |
| 10 | Processing and properties of zirconium diboride-based composites显示文摘 | MONTEVERDE F BELLOSI A GUICCIARDI S | 2002 | J Eur Ceram Soc2002，22，： | 1 |
| 11 | Development and characterization of metal-diboride-based composites toughened with ultra-fine SiC par- ticulates 显示文摘 | MONTEVERDE F BELLOSI A | 2005 | Solid State Sci2005，7，25： | 1 |
| 12 | Progress in the fabrication of ultra-hightemperature ceramics:'in situ' synthesis,microstructure and properties of a reactive hot-pressed HfB2-SiC composite显示文摘 | Monteverde F | | 0，，： | 1 |
| 13 | Oxidation and burner rig corrosion of liquid phase sintered SiC 显示文摘 | Baxter D Bellosi A Monteverde F | 2000 | Journal of the European Ceramic Society2000，20，： | 1 |
| 14 | Beneficial effects of an ultra-fine a-SiC incorpora- tion on the sinterability and mechanical properties of ZrB2 显示文摘 | MONTEVERDE F | 2006 | Appl Phys A2006，82，2： | 1 |
| 15 | Advances in microstructure and mechanical properties of zirconium diboride based ceramics 显示文摘 | Monteverde F Guicciardi S Bellosi A | 2003 | Mater Sci Eng2003，346，12： | 1 |
| 16 | Processing and properties of Ti(C,N)-WC-based materials显示文摘 | BELLOSI Alid A MEDRI Valentina MONTEVERDE Frédéric | 2001 | J Am Ceram Soc2001，84，11： | 1 |
| 17 | Comparison of ZrB2-ZrC-SiC composites fabricated by spark plasma sintering and hot-pressing显示文摘 | MEDRI V MONTEVERDE F BALBO A | 2005 | Adv Eng Mater2005，7，3： | 1 |
| 18 | The thermal stability in air of hot-pressed diboride matrix composites for uses at uhra-high temperatures 显示文摘 | Monteverde F | 2005 | Corrosion Science2005，47，9： | 1 |
| 19 | 显示文摘 | Monteverde F Bellosi A Guicciardi S | 2002 | J Eur Ceram Soc2002，22，3： | 1 |
| 20 | Supplier Switching Costs and Vertical Integration in the Automobile Industry显示文摘 | Monteverde kirk and David Tcece | 1982 | Bell Journal of Economics1982，13，： | 1 |
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