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| 1 | Adenoviral gene therapy in gastric cancer: A review显示文摘Gastric cancer is one of the most common malignancies worldwide. With current therapeutic approaches the prognosis of gastric cancer is very poor, as gastric cancer accounts for the second most common cause of death in cancer related deaths. Gastric cancer like almost all other cancers has a molecular genetic basis which relies on disruption in normal cellular regulatory mechanisms regarding cell growth, apoptosis and cell division. Thus novel therapeutic approaches such as gene therapy promise to become the alternative choice of treatment in gastric cancer. In gene therapy, suicide genes, tumor suppressor genes and anti-angiogenesis genes among many others are introduced to cancer cells via vectors. Some of the vectors widely used in gene therapy are Adenoviral vectors. This review provides an update of the new developments in adenoviral cancer gene therapy including strategies for inducing apoptosis, inhibiting metastasis and targeting the cancer cells. | Nima Khalighinejad Hesammodin Hariri Omid Behnamfar Arash Yousefi Amir Momeni | 2008 | World Journal of Gastroenterology2008，14，2： | 16 |
| 2 | Hot deformation behavior of microstructural constituents in a duplex stainless steel during high-temperature straining显示文摘The hot deformation characteristics of 1.4462 duplex stainless steel(DSS)were analyzed by considering strain partitioning between austenite and ferrite constituents.The individual behavior of ferrite and austenite in microstructure was studied in an iso-stress condition.Hot compression tests were performed at temperatures of 800-1100 C and strain rates of 0.001-1 s 1.The flow stress was modeled by a hyperbolic sine constitutive equation,the corresponding constants and apparent activation energies were determined for the studied alloys.The constitutive equation and law of mixture were used to measure the contribution factor of each phase at any given strain.It is found that the contribution factor of ferrite exponentially declines as the Zener-Hollomon parameter(Z)increases.On the contrary,the austenite contribution polynomially increases with the increase of Z.At low Z values below 2.6.×1015(lnZ=35.5),a negative contribution factor is determined for austenite that is attributed to dynamic recrystallization.At high Z values,the contribution factor of austenite is about two orders of magnitude greater than that of ferrite,and therefore,austenite can accommodate more strain.Microstructural characterization via electron back-scattered difraction(EBSD)confirms the mechanical results and shows that austenite recrystallization is possible only at high temperature and low strain rate. | Amir Momeni Shahab Kazemi Ali Bahrani | 2013 | International Journal of Minerals,Metallurgy and Materials2013，20，10： | 11 |
| 3 | The Role and Function of Ras-association domain family in Cancer:A Review显示文摘Ras gene mutation has been observed in more than 30%of cancers,and 90%of pancreatic,lung and colon cancers.Ras proteins(K-Ras,H-Ras,N-Ras)act as molecular switches which are activated by binding to GTP.They play a role in the cascade of cell process control(proliferation and cell division).In the inactive state,transforming GTP to GDP leads to the activation of GTpase in Ras gene.However,the mutation in Ras leads to the loss of internal GTPase activity and permanent activation of the protein.The activated Ras can promote the cell death or stop cell growth,which are facilitated by Ras-association domain family.Various studies have been conducted to determine the importance of losing RASSF proteins in Rasinduced tumors.This paper examines the role of Ras and RASSF proteins.In general,RASSF proteins can be used as a suitable means for targeting a large group of Ras-induced tumors. | Mohammad Reza Zinatizadeh Seyed Ali Momeni Peyman Kheirandish Zarandi Ghanbar Mahmoodi Chalbatani Hassan Dana Hamid Reza Mirzaei Mohammad Esmaeil Akbari Seyed Rouhollah Miri | 2019 | Genes & Diseases2019，6，4： | 10 |
| 4 | Hot Compression Behavior of As-Cast Precipitation-Hardening Stainless Steel显示文摘High temperature deformation characteristics of a semiaustenitic grade of precipitation-hardening stainless steels were investigated by conducting hot compression tests at temperatures of 900-1 100 ℃ and strain rates of 0.001-1 s-1. Flow behavior of this alloy was investigated and it was realized that dynamic recrystallization (DRX) was responsible for flow softening. The correlation between critical strain for initiation of DRX and deformation parameters including temperature and strain rate, and therefore, Zener-Hollomon parameter (Z) was studied. Metallographic observation was performed to determine the as-deformed microstructure. Microstructural observation shows that recrystallized grain size increases with increasing the temperature and decreasing the strain rate. The activation energy required for DRX of the investigated steel was determined using correlations of flow stress versus temperature and strain rate. The calculated value of activation energy, 460 kJ/mol, is in accordance with other studies on stainless steels. The relationship between peak strain and Z parameter is proposed. | A Momeni S M Abbasi A Shokuhfar | 2007 | Journal of Iron and Steel Research(International)2007，14，5： | 9 |
| 5 | Effect of Heat Treatment on Microstructure of Modified Cast AISI D3 Cold Work Tool Steel显示文摘The effects of heat treatment on the microstructure of modified cast high chromium high carbon AISI D3 steel were studied.The modified AISI D3 steel was developed by replacing part of chromium with niobium and titanium,in which chromium carbide was partially replaced with MC carbides.The cast samples produced by investment casting were heat treated under different conditions.The microstructures of the samples were studied by optical microscope and scanning electron microscope equipped with EDS analyzer.To determine the optimized homogenizing process,the effects of homogenizing treatment on the microstructure and the morphology of carbides were also studied.The results show that the MC carbides are not changed in shape and amounts during high temperature homogenizing,whereas the M3C carbides are reduced in amount and become semiglobular in shape,and the homogeneity of microstructure is improved. | Shahram Kheirandish Hasan Saghafian Jalal Hedjazi Mohammad Momeni | 2010 | Journal of Iron and Steel Research(International)2010，17，9： | 8 |
| 6 | Interventions of natural and synthetic agents in inflammatory bowel disease, modulation of nitric oxide pathways显示文摘Inflammatory bowel disease(IBD)refers to a group of disorders characterized by chronic inflammation of the gastrointestinal(GI)tract.The elevated levels of nitric oxide(NO)in serum and affected tissues;mainly synthesized by the inducible nitric oxide synthase(iNOS)enzyme;can exacerbate GI inflammation and is one of the major biomarkers of GI inflammation.Various natural and synthetic agents are able to ameliorate GI inflammation and decrease iNOS expression to the extent comparable with some IBD drugs.Thereby,the purpose of this study was to gather a list of natural or synthetic mediators capable of modulating IBD through the NO pathway.Electronic databases including Google Scholar and PubMed were searched from 1980 to May 2018.We found that polyphenols and particularly flavonoids are able to markedly attenuate NO production and iNOS expression through the nuclear factorκB(NF-κB)and JAK/STAT signaling pathways.Prebiotics and probiotics can also alter the GI microbiota and reduce NO expression in IBD models through a broad array of mechanisms.A number of synthetic molecules have been found to suppress NO expression either dependent on the NF-κB signaling pathway(i.e.,dexamethasone,pioglitazone,tropisetron)or independent from this pathway(i.e.,nicotine,prednisolone,celecoxib,β-adrenoceptor antagonists).Co-administration of natural and synthetic agents can affect the tissue level of NO and may improve IBD symptoms mainly by modulating the Toll like receptor-4 and NF-κB signaling pathways. | Aida Kamalian Masoud Sohrabi Asl Mahsa Dolatshahi Khashayar Afshari Shiva Shamshiri Nazanin Momeni Roudsari Saeideh Momtaz Roja Rahimi Mohammad Abdollahi Amir Hossein Abdolghaffari | 2020 | World Journal of Gastroenterology2020，26，24： | 5 |
| 7 | 动态张拉载荷作用下花岗岩的层裂破坏机理显示文摘在动态载荷作用下岩石可能发生层裂破坏。在动态霍普金森压杆(SHPB)上及4种不同的冲击载荷条件下,开展动态张拉载荷作用下花岗岩的破裂发展和破坏特性研究。岩样破坏后,在破坏表面附近取样并制作薄片,用偏光显微镜观察岩石裂纹的生长模式,并利用扫描电子显微镜(SEM)观察破坏表面的矿物颗粒形貌特征,从而评价岩石矿物特征对载荷和破坏的响应特性。研究结果表明,岩样层裂裂纹数量随着峰值冲击载荷的增加而增多,并且岩石内的石英矿物持续发生大量的晶间断裂;矿物晶体的解理面及其相对于载荷的方向对岩石强度和破裂特性有着至关重要的作用;沿垂直于载荷的矿物晶体解理面进行分离而没有云母矿物平行于载荷的运动是岩石发生层裂破坏所特有的。 | 黄麟淇 汪军 Aliakbar MOMENI 王少锋 | 2021 | Transactions of Nonferrous Metals Society of China2021，31，7： | 5 |
| 8 | A new impedance and robust adaptive inverse control approach for a teleoperation system with varying time delay显示文摘This paper presents a new robust adaptive inverse control approach for a force-reflecting teleoperation system with varying time delay. First,an impedance control is designed for the master robot. Second,an adaptive inverse control is proposed for the slave robot. Finally,the slave side controller is modified such that the robust stability and performance are achieved. In addition,robust stability analysis has been performed and optimal behavior is ensured by using standard characteristic polynomials. It is shown that despite of presence of randomly-varying time delay,the proposed control algorithm compensates the position drifts efficiently. Demonstrable simulation studies confirm the effectiveness of the proposed control system and its advantages over the existing sliding mode control strategies. | Mokhtar SHA SADEGHI Hamid Reza MOMENI | 2009 | Science China(Technological Sciences)2009，52，9： | 5 |
| 9 | Multiscale computational understanding and growth of 2D materials:a review显示文摘The successful discovery and isolation of graphene in 2004,and the subsequent synthesis of layered semiconductors and heterostructures beyond graphene have led to the exploding field of two-dimensional(2D)materials that explore their growth,new atomic-scale physics,and potential device applications.This review aims to provide an overview of theoretical,computational,and machine learning methods and tools at multiple length and time scales,and discuss how they can be utilized to assist/guide the design and synthesis of 2D materials beyond graphene. | Kasra Momeni Yanzhou Ji Yuanxi Wang Shiddartha Paul Sara Neshani Dundar E.Yilmaz Yun Kyung Shin Difan Zhang Jin-Wu Jiang Harold S.Park Susan Sinnott Adri van Duin Vincent Crespi Long-Qing Chen | 2020 | npj Computational Materials2020，，1： | 4 |
| 10 | Dye-sensitized solar cells based on Cr-doped TiO2 nanotube photoanodes显示文摘The effect of chromium doping on the photovoltaic efficiency of dye-sensitized solar cells(DSSCs) with anodized TiO_2 nanotubes followed by an annealing process was investigated. Cr-doped TiO_2 nanotubes(CrTNs) with different amounts of chromium were obtained by anodizing of titanium foils in a single-step process using potassium chromate as the chromium source. Film features were investigated by scanning electron microscopy(SEM), X-ray diffraction(XRD), energy-dispersive X-ray spectroscopy(EDX), and ultraviolet-visible(UV-Vis) spectroscopy. It is clearly seen that highly ordered TiO_2 nanotubes are formed in an anodizing solution free of potassium chromate, and with a gradual increase in the potassium chromate concentration, these nanotube structures change to nanoporous and compact films without porosity. The photovoltaic efficiencies of fabricated DSSCs were characterized by a solar cell measurement system via the photocurrent-voltage(I-V) curves. It is found that the photovoltaic efficiency of DSSCs with CrTNsl sample is improved by more than three times compared to that of DSSCs with undoped TNs. The energy conversion efficiency increases from 1.05 % to 3.89 % by doping of chromium. | M. M. Momeni | 2017 | Rare Metals2017，36，11： | 4 |
| 11 | Characterization of hot deformation behavior of 410 martensitic stainless steel using constitutive equations and processing maps显示文摘 | A. Momeni K. Dehghani | 2010 | Materials Science & Engineering A2010，，21： | 4 |
| 12 | 问荆提取物页岩水化膨胀抑制剂性能及防膨机理显示文摘提出将问荆提取物作为页岩水化膨胀抑制剂,通过室内实验研究了其抑制页岩水化膨胀的性能,与氯化钾和聚胺进行了对比,并分析了其防膨机理。膨润土水化抑制实验、膨润土沉淀实验、动态线性膨胀实验、滚动回收实验和吸附量测定实验结果表明:问荆提取物可以抑制膨润土的水化,阻止黏土矿物在溶液中均匀分散,减小膨润土的膨胀,抑制钻屑在水中破碎和分散,且与氯化钾和聚胺性能相当。对问荆提取物的防膨机理进行分析后发现:其成分中具有活性烃基的物质与膨润土颗粒表面间氢键缔合,降低了膨润土颗粒表面的吸水率,从而抑制膨润土膨胀。除了具有良好的防膨能力,问荆提取物获取容易、价格低廉,且不会破坏生态环境,是一种理想的页岩水化膨胀抑制剂。 | BARATI Pezhman KESHTKAR Sadegh AGHAJAFARI Amirhossein SHAHBAZI Khalil MOMENI Ali | 2016 | 石油勘探与开发2016，43，3： | 4 |
| 13 | Importance of reporting segmental bowel preparation scores during colonoscopy in clinical practice显示文摘AIM: To evaluate the impact of reporting bowel preparation using Boston Bowel Preparation Scale(BBPS) in clinical practice.METHODS: The study was a prospective observational cohort study which enrolled subjects reporting for screening colonoscopy. All subjects received a gallon of polyethylene glycol as bowel preparation regimen. After colonoscopy the endoscopists determined quality of bowel preparation using BBPS. Segmental scores were combined to calculate composite BBPS. Site and size of the polyps detected was recorded. Pathology reports were reviewed to determine advanced adenoma detection rates(AADR). Segmental AADR's were calculated and categorized based on the segmental BBPS to determine the differential impact of bowel prep on AADR. RESULTS: Three hundred and sixty subjects were enrolled in the study with a mean age of 59.2 years, 36.3% males and 63.8% females. Four subjects with incomplete colonoscopy due BBPS of 0 in any segment were excluded. Based on composite BBPS subjects were divided into 3 groups; Group-0(poor bowel prep, BBPS 0-3) n = 26(7.3%), Group-1(Suboptimal bowel prep, BBPS 4-6) n = 121(34%) and Group-2(Adequate bowel prep, BBPS 7-9) n = 209(58.7%). AADR showed a linear trend through Group-1 to 3; with an AADR of 3.8%, 14.8% and 16.7% respectively. Also seen was a linear increasing trend in segmental AADR with improvement in segmental BBPS. There was statistical significant difference between AADR among Group 0 and 2(3.8% vs 16.7%, P < 0.05), Group 1 and 2(14.8% vs 16.7%, P < 0.05) and Group 0 and 1(3.8% vs 14.8%, P < 0.05). χ2 method was used to compute P value for determining statistical significance.CONCLUSION: Segmental AADRs correlate with segmental BBPS. It is thus valuable to report segmental BBPS in colonoscopy reports in clinical practice. | Deepanshu Jain Mojdeh Momeni Mahesh Krishnaiah Sury Anand Shashideep Singhal | 2015 | World Journal of Gastroenterology2015，21，13： | 4 |
| 14 | Dynamic recrystallization and precipitation in high manganese austenitic stainless steel during hot compression显示文摘Dynamic recrystallization and precipitation in a high manganese austenitic stainless steel were investigated by hot compression tests over temperatures of 950-1150°C at strain rates of 0.001 s-1-1 s-1.All the flow curves within the studied deformation regimes were typical of dynamic recrystallization.A window was constructed to determine the value of apparent activation energy as a function of strain rate and deformation temperature.The kinetics of dynamic recrystallization was analyzed using the Avrami kinetics equation.A range of apparent activation energy for hot deformation from 303 kJ/mol to 477 kJ/mol is obtained at different deformation regimes.Microscopic characterization confirms that under a certain deformation condition(medium Zener-Hollomon parameter(Z) values),dynamic recrystallization appears at first,but large particles can not inhibit the recrystallization.At low or high Z values,dynamic recrystallization may occur before dynamic precipitation and proceeds faster.In both cases,secondary phase precipitation is observed along prior austenite grain boundaries.Stress relaxation tests at the same deformation temperatures also confirm the possibility of dynamic precipitation.Unexpectedly,the Avrami's exponent value increases with the increase of Z value.It is associated with the priority of dynamic recrystallization to dynamic precipitation at higher Z values. | Amir Momeni Shahab Kazemi Golam Ebrahimi Alireza Maldar | 2014 | International Journal of Minerals,Metallurgy and Materials2014，21，1： | 3 |
| 15 | Generating one-,two-,three-and four-scroll attractors from a novel four-dimensional smooth autonomous chaotic system显示文摘A new four-dimensional quadratic smooth autonomous chaotic system is presented in this paper,which can exhibit periodic orbit and chaos under the conditions on the system parameters.Importantly,the system can generate one-,two-,three-and four-scroll chaotic attractors with appropriate choices of parameters.Interestingly,all the attractors are generated only by changing a single parameter.The dynamic analysis approach in the paper involves time series,phase portraits,Poincar'e maps,a bifurcation diagram,and Lyapunov exponents,to investigate some basic dynamical behaviours of the proposed four-dimensional system. | Sara Dadras Hamid Reza Momeni | 2010 | Chinese Physics B2010，19，6： | 3 |
| 16 | Factors influencing pre-hospital delay among patients with acute myocardial infarction in Iran显示文摘 | Maryam Momeni Arsalan Salari Shora Shafighnia Atefeh Ghanbari Fardin Mirbolouk | 2012 | Chinese Medical Journal2012，，19： | 3 |
| 17 | Effects of Hydro-alcoholic Extract of Launaea acanthodes on Serum Gonadotropin and Testosterone Levels and the Structure of Seminiferous Tubules in Hyperglycemic Rats显示文摘Objective:To investigate the effects of hydro-alcoholic extract of Launaea acanthodes,a blood glucose lowering plant in folk medicine of Iran,on the structure of seminiferous tubules and serum gonadotropin and testosterone levels in hyperglycemic rats.Methods:Twenty-four Wistar rats were randomly allocated into4 groups(n=6):control,streptozotocin(STZ),STZ+insulin[STZ+Ins,5 IU/(kg·day)],and STZ+Launaea acanthodes extract[STZ+Ext,150 mg/(kg·day)].Blood samples were collected at the 2nd and 4th weeks for detection of testosterone,follicle stimulating hormone(FSH)and luteinizing hormone(LH)with enzyme-linked immuno sorbent assay(ELISA),and the right testes of rats were removed at the 7th week for the evaluation of diameter and wall thickness of seminiferous tubules and number of Leydig cells using unbiased stereological techniques.Results:In comparison with the control group,at the 2nd week FSH(0.45 vs 0.03,0.02,0.02 IU/L in STZ,STZ+Ins and STZ+Ext groups,respectively)and LH(1.02 vs 0.37,0.2,0.29 IU/L)showed significant decreases(all P<0.05)and testosterone(4.2 vs 8.37,7.78,11.8 ng/mL)showed a remarkable increase(all P<0.05).The levels of these hormones became closer in the STZ+Ext and the STZ+Ins groups to the control at the 4th week.A significant decrease in diameter and wall thickness of seminiferous tubules and number of Leydig cells were observed in the STZ group as compared with the control(P<0.01).Conclusions:Administration of Launaea extract demonstrated a beneficial impact on the protection of testis from pathogenic and degenerative effects of hyperglycemia which may be partly due to its potential antioxidative effects. | Ameneh Mohammadi Morteza Behnam-Rassouli Zeinab Momeni Naser Mahdavi-Shahri | 2016 | Chinese Journal of Integrative Medicine2016，22，3： | 2 |
| 18 | 4D打印定律显示文摘三维(3D)打印是一种增材制造(AM)工艺。相应地,四维(4D)打印是一个涉及多个研究领域的制造工艺。4D打印保留了3D打印的一般属性(如减少材料浪费,消除注射模具、冲压模具和机械加工过程),并且随着时间的推移能实现产品第四维度的智能行为。在打印过程中,这种智能行为(通常由逆数学问题)编码进刺激响应多材料中,并在打印后通过刺激该材料来实现。3D和4D打印结构的主要区别是4D打印存在一个附加的维度,这个维度可以随着时间的推移进行智能进化。然而,目前还没有用于建模和预测这个附加维度的一般公式。本文从基本原理开始,导出并验证了一个具有特定形式的一般双指数公式,该公式可以模拟几乎所有4D结构的时间相关性行为(如水、光化学、光热、溶剂、pH、湿度、电化学、电热、超声波等响应)。研究表明,需要利用两种类型的时间常数来捕捉4D多材料的正确的时间相关性行为。本文引入了4D多材料结构中主动材料和被动材料的界面错配压力的概念,从而得到了两个时间常数之一。本文从几乎所有刺激响应材料的时间相关性行为的统一模型中开发和提取了另一个时间常数。本文的结果从最基本的概念开始,并以控制方程结束,可以作为未来4D打印领域研究的一般设计原则,其中时间相关性行为应该被正确地理解、建模和预测。 | Farhang Momeni Jun Ni | 2020 | Engineering2020，6，9： | 2 |
| 19 | Evaluation of factors affecting psychological morbidity in emergency medicine practitioners显示文摘BACKGROUND: Assessing and evaluating mental health status can provide educational planners valuable information to predict the quality of physicians' performance at work. These data can help physicians to practice in the most desired way. The study aimed to evaluate factors affecting psychological morbidity in Iranian emergency medicine practitioners at educational hospitals of Tehran.METHODS: In this cross sectional study 204 participants(emergency medicine residents and specialists) from educational hospitals of Tehran were recruited and their psychological morbidity was assessed by using a 28-question Goldberg General Health Questionnaire(GHQ-28). Somatization, anxiety and sleep disorders, social dysfunction and depression were evaluated among practitioners and compared to demographic and job related variables.RESULTS: Two hundreds and four participants consisting of 146(71.6%) males and 58(28.4%) females were evaluated. Of all participants, 55(27%) were single and 149(73%) were married. Most of our participants(40.2%) were between 30–35 years old. By using GHQ-28, 129(63.2%) were recognized as normal and 75(36.8%) suffered some mental health disorders. There was a signifi cant gender difference between normal practitioners and practitioners with disorder(P=0.02) while marital status had no significant difference(P=0.2). Only 19(9.3%) declared having some major mental health issue in the previous month.CONCLUSION: Females encountered more mental health disorders than male(P=0.02) and the most common disorder observed was somatization(P=0.006). | Mehdi Momeni Farshid Fahim Elnaz Vahidi Amir Nejati Morteza Saeedi | 2016 | World Journal of Emergency Medicine2016，7，3： | 2 |
| 20 | Human microbiome and prostate cancer development:current insights into the prevention and treatment显示文摘The huge communities of microorganisms that symbiotically colonize humans are recognized as significant players in health and disease.The human microbiome may influence prostate cancer development.To date,several studies have focused on the effect of prostate infections as well as the composition of the human microbiome in relation to prostate cancer risk.Current studies suggest that the microbiota of men with prostate cancer significantly differs from that of healthy men,demonstrating that certain bacteria could be associated with cancer development as well as altered responses to treatment.In healthy individuals,the microbiome plays a crucial role in the maintenance of homeostasis of body metabolism.Dysbiosis may contribute to the emergence of health problems,including malignancy through affecting systemic immune responses and creating systemic inflammation,and changing serum hormone levels.In this review,we discuss recent data about how the microbes colonizing different parts of the human body including urinary tract,gastrointestinal tract,oral cavity,and skin might affect the risk of developing prostate cancer.Furthermore,we discuss strategies to target the microbiome for risk assessment,prevention,and treatment of prostate cancer. | Solmaz Ohadian Moghadam Seyed Ali Momeni | 2021 | Frontiers of Medicine2021，15，1： | 2 |
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