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| 1 | Comparison of perceived pain and patients’ satisfaction with traditional local anesthesia and single tooth anesthesia: A randomized clinical trial显示文摘BACKGROUND Contemporary innovations in the area of local anesthesia have attempted to provide an absolutely pain free experience for patients.Since the introduction of Computer-Controlled Local Anesthetic Delivery Systems to dentistry,many studies have compared its efficacy and safety to conventional anesthesia.However,very few studies have compared single tooth anesthesia(STA)and traditional local anesthesia.AIM To compare pain rating,changes in blood pressure,and heart rate during the local anesthetic injection.The secondary objectives were to measure the patients’level of satisfaction and the differences in anesthetic efficiency between the STA system and traditional local infiltration.METHODS A randomized controlled trial was conducted and a total of 80 patients with dental restorative needs were enrolled for the study.The patients were evaluated for their general physical status and oral clinical findings before enrollment.Information regarding perceived pain,changes in heart rate and blood pressure,and patients’satisfaction was collected using an electronic data form and was analyzed using paired and unpaired t-tests.RESULTS No significant difference was noted in perceived pain(P=0.59)and systolic blood pressure(P=0.09)during anesthetic injection using both traditional and STA techniques.STA patients had a significantly higher heart rate during anesthesia,although a statistically significant difference was noted among the traditional anesthesia and the STA groups even before anesthesia.During the restorative procedure,less pain was perceived by STA patients on the Wong-Baker FACES pain scale,which was statistically significant(P<0.001).Analyses of post-procedure patient responses showed that STA patients had a significantly better treatment experience and preferred to have the same method of injection in the future(P=0.04).CONCLUSION STA system can provide less painful and more comfortable restorative treatment procedures in comparison to the traditional infiltration technique. | Mohammad I Al-Obaida Mehdiya Haider Rawan Hashim Wafa AlGheriri Sree Lalita Celur Samar A Al-Saleh Ebtissam M Al-Madi | 2019 | World Journal of Clinical Cases2019，7，19： | 8 |
| 2 | Trends in treatment and overall survival among patients with proximal esophageal cancer显示文摘BACKGROUND The management of proximal esophageal cancer differs from that of tumors located in the mid and lower part of the esophagus due to the close vicinity of vital structures.Non-surgical treatment options like radiotherapy and definitive chemoradiation(CRT)have been implemented.The trends in(non-)surgical treatment and its impact on overall survival(OS)in patients with proximal esophageal cancer are unclear,related to its rare disease status.To optimize treatment strategies and counseling of patients with proximal esophageal cancer,it is therefore essential to gain more insight through real-life studies.AIM To establish trends in treatment and OS in patients with proximal esophageal cancer.METHODS In this population-based study,patients with proximal esophageal cancer diagnosed between 1989 and 2014 were identified in the Netherlands Cancer Registry.The proximal esophagus consists of the cervical esophagus and the upper thoracic section,extending to 24 cm from the incisors.Trends in radiotherapy,chemotherapy,and surgery,and OS were assessed.Analyses were stratified by presence of distant metastasis.Multivariable Cox proportional hazards regression analyses was performed to assess the effect of period of diagnosis on OS,adjusted for patient,tumor,and treatment characteristics.RESULTS In total,2783 patients were included.Over the study period,the use of radiotherapy,resection,and CRT in non-metastatic disease changed from 53%,23%,and 1%in 1989-1994 to 21%,9%,and 49%in 2010-2014,respectively.In metastatic disease,the use of chemotherapy and radiotherapy increased over time.Median OS of the total population increased from 7.3 mo[95%confidence interval(CI):6.4-8.1]in 1989-1994 to 9.5 mo(95%CI:8.1-10.8)in 2010-2014(logrank P<0.001).In non-metastatic disease,5-year OS rates improved from 5%(95%CI:3%-7%)in 1989-1994 to 13%(95%CI:9%-17%)in 2010-2014(logrank P<0.001).Multivariable regression analysis demonstrated a significant treatment effect over time on survival.In metastatic disease,median OS was 3.8 mo(95%CI:2.5-5.1)in 1989-1994,and 5.1 mo(95%CI:4.3-5.9)in 2010-2014(logrank P=0.26).CONCLUSION OS significantly improved in non-metastatic proximal esophageal cancer,likely to be associated with an increased use of CRT.Patterns in metastatic disease did not change significantly over time. | Judith de Vos-Geelen Sandra ME Geurts Liselot BJ Valkenburg-van Iersel Evelien JM de Jong Vivianne CG Tjan-Heijnen Margreet van Putten Valery EPP Lemmens Heike I Grabsch Nadia Haj Mohammad Frank JP Hoebers Chantal V Hoge Paul M Jeene Hanneke WM van Laarhoven Tom Rozema Marije Slingerland Grard AP Nieuwenhuijzen | 2019 | World Journal of Gastroenterology2019，25，47： | 2 |
| 3 | Elasto-plastic buckling of perforated plates under uniaxial compression 显示文摘 | Khaled M E Aly S N Mohammad I M | 2004 | Thin-Walled Structures2004，42，： | 1 |
| 4 | Analysis and design of sprinkler irrigation laterals显示文摘 | HATHOOT H M AL-AMOUD A I MOHAMMAD F S | 1994 | Irrig Drain Eng1994，120，3： | 1 |
| 5 | A prospective multicenter study to evaluate the feasibility and safety of aggressive antihypertensive treatment in patients with acute intracerebral hemorrhage显示文摘 | Qureshi A I Mohammad Y M Yahia A M | 2005 | J Intensive Care Med2005，20，1： | 1 |
| 6 | Detection of DNA damage induced by apoptosis in the rat brain following incomplete ischemia显示文摘 | Nadira I mohammad A Akiyoshi M | 1995 | Neurosci Letter1995，188，： | 1 |
| 7 | Recent advances on tea polyphenols显示文摘 | Kanwar J Taskeen M Mohammad I | 2012 | Front Biosci(Elite Ed)2012，4，： | 1 |
| 8 | Polymer nanocomposites containing carbon nanotube 显示文摘 | Mohammad M Winey K I | 2006 | Macromolecules2006，39，16： | 1 |
| 9 | Stabilization of electrostatic MEMS resonators using a delayed feedback controller 显示文摘 | Fadi M A Mohammad I Y | 2010 | Smart Materials and Structures2010，19，03： | 1 |
| 10 | Value of composted organic wastes as an alternative to synthetic fertilizers for soil quality improvement and increased yiled 显示文摘 | Mohammad H G Denney M J Clancy I | 2007 | Compost Science Utilization2007，15，4： | 1 |
| 11 | Application of a sliding mode observer for position and speed estimation in switched reluctance motor drives显示文摘 | Roy A M Mohammad S I Iqbal H | 2001 | IEEE Transactions on Industry Applications2001，37，1： | 1 |
| 12 | On the nonlinear resonances and dynamic pull-in of electrostatically actuated resonators显示文摘 | Fadi M A Mohammad I Y Hassen M O | | 0，，04： | 1 |
| 13 | Stabilization of electrostatic MEMS resonators using a delayed feedback controller显示文摘 | Fadi M A Mohammad I Y | | 0，，03： | 1 |
| 14 | Recent advances on tea polyphenols显示文摘 | Kanwar J Taskeen M Mohammad I | 2012 | Front Biosci (Elite Ed)2012，4，： | 1 |
| 15 | Hypolipidemic and antioxidant properties of tocotrienol rich fraction isolated fromrice bran oil in experimentally induced hyperlipidemic rats 显示文摘 | Mohammad M Zafarul H B Jahangir I | 2005 | Food and Chemical Toxicology2005，43，： | 1 |
| 16 | Assessment of Residential Sat- isfaction in Newly Designed Public Low-Cost Housing in Kuala Lum- pur, Malaysia显示文摘 | Mohammad A M Mansor I Yong R R | 2010 | Habitat International Volume 34 Issue 1 January 20102010，34，1： | 1 |
| 17 | Experimental study on evaluation and optimization of conversion of waste animal fat into biodiesel显示文摘 | Ghassan M Tashtoush Mohamad I Mohammad M | 2004 | Energy Conversion and Management2004，45，： | 1 |
| 18 | Percutane- ous needle peritoneal biopsy in the diagnosis of exudative ascites 显示文摘 | MAHMOOD K SAEEDI M I MOHAMMAD R | 2008 | J Ayub Med Coll Abbottabad2008，20，4： | 1 |
| 19 | Hierarchical cluste-ring approach for determination of isomorphism among planar kine-matic chains and their derived mechanisms显示文摘 | LOHUMI M K MOHAMMAD A KHAN I A | 2012 | Journal of mechani-cal science and technology2012，26，12： | 1 |
| 20 | Application of a sliding mode observer for position and speed estimation in switched reluctance motor drives显示文摘 | ROY A M C MOHAMMAD S I | 2001 | IEEE Transactions on Industry Application2001，37，1： | 1 |
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