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| 1 | p16 promoter hypermethylation:A useful serum marker for early detection of gastric cancer显示文摘AIM: To determine p16 promoter hypermethylation in gastric tumoral tissue and serum samples, its impact on p16-protein expression, and correlation with clinical and histological features. METHODS: Samples were obtained from 52 histologically confirmed cases of gastric adenocarcinoma. Gastric tissue and serum of 50 age- and sex-matched individuals with normal gastroscopy and biopsy were obtained as control samples. Methylation-specific polymerase chain reaction (MSP) was used to evaluate methylation status of p16 promoter. p16-protein expression was analyzed by immunohistochemical staining on paraffin-embedded sections. RESULTS: Methylation was detected in 44.2% (23/52) of tumoral tissues. 60.9% of them were also methylated in serum, i.e., 26.9% of all patients (14/52). Methylation was not detected in tissue and sera of control samples. p16-protein expression was decreased in 61.5% of cases (32/52), and was significantly associated with promoter hypermethylation (P < 0.001). Methylation was significantly more frequent in higher pathological grades (P < 0.05). Methylation was not associated with other clinicopathological features and environmental factors including H pylori infection and smoking. CONCLUSION: p16 promoter hypermethylation is an important event in gastric carcinogenesis. It is the principle mechanism of p16 gene silencing. It is related to malignant tumor behavior. Detection of DNA methylation in serum may be a biomarker for early detection of gastric cancer. | Mohammad Reza Abbaszadegan Omeed Moaven Hamid Reza Sima Kamran Ghafarzadegan Azadeh A'rabi Mohammad Naser Forghani Hamid Reza Raziee Ali Mashhadinejad Mostafa Jafarzadeh Ehsan Esmaili-Shandiz Ezzat Dadkhah | 2008 | World Journal of Gastroenterology2008，14，13： | 50 |
| 2 | Accuracy of urea breath test in Helicobacter pylori infection: Meta-analysis显示文摘AIM: To quantitatively summarize and appraise the available evidence of urea breath test(UBT) use to diagnose Helicobacter pylori(H. pylori) infection in patients with dyspepsia and provide pooled diagnostic accuracy measures.METHODS: We searched MEDLINE, EMBASE, Cochrane library and other databases for studies addressing the value of UBT in the diagnosis of H. pylori infection. We included cross-sectional studies that evaluated the diagnostic accuracy of UBT in adult patients with dyspeptic symptoms. Risk of bias was assessed using QUADAS(Quality Assessment of Diagnostic Accuracy Studies)-2 tool. Diagnostic accuracy measures were pooled using the random-effects model. Subgroup analysis was conducted by UBT type(13C vs 14C) and by measurement technique(Infrared spectrometry vs Isotope Ratio Mass Spectrometry).RESULTS: Out of 1380 studies identified, only 23 met the eligibility criteria. Fourteen studies(61%) evaluated 13 C UBT and 9 studies(39%) evaluated 14 C UBT. There was significant variation in the type of reference standard tests used across studies.Pooled sensitivity was 0.96(95%CI: 0.95-0.97) andpooled specificity was 0.93(95%CI: 0.91-0.94). Likelihood ratio for a positive test was 12 and for a negative test was 0.05 with an area under thecurve of 0.985. Meta-analyses were associated with a significant statistical heterogeneity that remained unexplained after subgroup analysis. The included studies had a moderate risk of bias.CONCLUSION: UBT has high diagnostic accuracy for detecting H. pylori infection in patients with dyspepsia. The reliability of diagnostic meta-analytic estimates however is limited by significant heterogeneity. | Mazen Ferwana Imad Abdulmajeed Ali Alhajiahmed Wedad Madani Belal Firwana Rim Hasan Osama Altayar Paul J Limburg Mohammad Hassan Murad Bandar Knawy | 2015 | World Journal of Gastroenterology2015，21，4： | 45 |
| 3 | Hepatitis B virus,HBx mutants and their role in hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC)is one of the leading causes of death induced by cancer in the modern world and majority of the cases are related to chronic hepatitis B virus(HBV)infection.HBV-encoded X protein(HBx)is known to play a pivotal role in the pathogenesis of viral induced HCC.HBx is a multifunctional protein of17 kDa which modulates several cellular processes by direct or indirect interaction with a repertoire of host factors resulting in HCC.HBX might interfere with several cellular processes such as oxidative stress,DNA repair,signal transduction,transcription,protein degradation,cell cycle progression and apoptosis.A number of reports have indicated that HBx is one of the most common viral ORFs that is often integrated into the host genome and its sequence variants play a crucial role in HCC.By mutational or deletion analysis it was shown that carboxy terminal of HBx has a likely role in protein-protein interactions,transcriptional transactivation,DNA repair,cell,signaling and pathogenesis of HCC.The accumulated evidence thus far suggests that it is difficult to understand the mechanistic nature of HBx associated HCC,and HBx mediated transcriptional transactivation and signaling pathways may be a major determinant.This article addresses the role of HBx in the development of HCC with particular emphasis on HBx mutants and their putative targets. | Ashraf Ali Hany Abdel-Hafiz Mohd Suhail Amany Al-Mars Mohammad Khalid Zakaria Kaneez Fatima Sultan Ahmad Esam Azhar Adeel Chaudhary Ishtiaq Qadri | 2014 | World Journal of Gastroenterology2014，20，30： | 29 |
| 4 | A handy review of carpal tunnel syndrome:From anatomy to diagnosis and treatment显示文摘Carpal tunnel syndrome(CTS) is the most commonly diagnosed disabling condition of the upper extremities. It is the most commonly known and prevalent type of peripheral entrapment neuropathy that accounts for about 90% of all entrapment neuropathies. This review aims to provide an outline of CTS by considering anat-omy, pathophysiology, clinical manifestation, diagnostic modalities and management of this common condition, with an emphasis on the diagnostic imaging evaluation. | Mohammad Ghasemi-rad Emad Nosair Andrea Vegh Afshin Mohammadi Adam Akkad Emal Lesha Mohammad Hossein Mohammadi Doaa Sayed Ali Davarian Tooraj Maleki-Miyoab Anwarul Hasan | 2014 | World Journal of Radiology2014，6，6： | 24 |
| 5 | Effi cacy of tricyclic antidepressants in irritable bowel syndrome:A meta-analysis显示文摘We aimed to evaluate the efficacy of tricyclic antidepressants(TCAs) as a therapeutic option for irritable bowel syndrome(IBS) through meta-analysis of randomized controlled trials.For the years 1966 until September 2008,PubMed,Scopus,Web of Science,and Cochrane Central Register of Controlled Trials were searched for double-blind,placebo-controlled trials investigating the effi cacy of TCAs in the management of IBS.Seven randomized,placebo-controlled clinical trials met our criteria and were included in the metaanalysis.TCAs used in the treatment arm of these trials included amitriptyline,imipramine,desipramine,doxepin and trimipramine.The pooled relative risk for clinical improvement with TCA therapy was 1.93(95% CI:1.44 to 2.6,P<0.0001).Effect size of TCAs versus placebo for mean change in abdominal pain score among the two studies was -44.15(95% CI:-53.27 to -35.04,P<0.0001).It is concluded that low dose TCAs exhibit clinically and statistically signifi cant control of IBS symptoms. | Roja Rahimi Shekoufeh Nikfar Ali Rezaie Mohammad Abdollahi | 2009 | World Journal of Gastroenterology2009，15，13： | 22 |
| 6 | Diabetes mellitus and cognitive impairments显示文摘There is strong evidence that diabetes mellitus increases the risk of cognitive impairment and dementia. Insulin signaling dysregulation and small vessel disease in the base of diabetes may be important contributing factors in Alzheimer's disease and vascular dementia pathogenesis, respectively. Optimal glycemic control in type 1 diabetes and identification of diabetic risk factors and prophylactic approach in type 2 diabetes are very important in the prevention of cognitive complications. In addition, hypoglycemic attacks in children and elderly should be avoided. Anti-diabetic medications especially Insulin may have a role in the management of cognitive dysfunction and dementia but further investigation is needed to validate these findings. | Elham Saedi Mohammad Reza Gheini Firoozeh Faiz Mohammad Ali Arami | 2016 | World Journal of Diabetes2016，7，17： | 23 |
| 7 | Effect of Salicylic Acid on Salinity-induced Changes in Brassica juncea显示文摘Seeds of Indian mustard (Brassica juncea (L.) Czern. et Coss.) were exposed to 0, 50, 100 and 150 mmol/L NaCl for 8 h and seeds were sown in an earthen pot. These stressed seedlings were subsequently sprayed with 10 μmol/L salicylic acid (SA) at 30 d and were sampled at 60 d to assess the changes in growth, photosynthesis and antioxidant enzymes. The seedlings raised from the seeds treated with NaCl had significantly reduced growth and the activities of carbonic anhydrase, nitrate reductase and photosynthesis, and the decrease was proportional to the increase in NaCl concentration. However, the antioxidant enzymes (catalase, peroxidase and superoxide dismutase) and proline content was enhanced in response to NaCl and/or SA treatment, where their interaction had an additive effect. Moreover, the toxic effects generated by the lower concentration of NaCl (50 mmol/L) were completely overcome by the application of SA. It was, therefore, concluded that SA ameliorated the stress generated by NaCl through the alleviated antioxidant system. | Mohammad Yusuf Syed Aiman Hasan Barket Ali Shamsul Hayat Qazi Fariduddin Aqil Ahmad | 2008 | Journal of Integrative Plant Biology2008，50，9： | 16 |
| 8 | Histological and biochemical alterations in early-stage lobar ischemia-reperfusion in rat liver显示文摘AIM:To investigate the structural and biochemical changes in the early stage of reperfusion in the rat livers exposed to lobar ischemia-reperfusion (IR).METHODS: The median and left lobes of the liver were subjected to 60 min ischemia followed by 5, 10, 30, 45, 60 and 120 min reperfusion. Blood samples were taken at different time intervals to test enzyme activities and biochemical alterations induced by reperfusion. At the end of each reperfusion period, the animals were killed by euthanasia and tissue samples were taken for histological examination and immunohistochemistry. RESULTS: Cell vacuolation, bleb formation and focal hepatitis were the most important changes occur during ischemia. While some changes including bleb formation were removed during reperfusion, other alterations including portal hepatitis, inflammation and the induction of apoptosis were seen during this stage. The occurrence of apoptosis, as demonstrated by apoptotic cells and bodies, was the most important histological change during reperfusion. The severity of apoptosis was dependent on the time of reperfusion, and by increasing the time of reperfusion,the numbers of apoptotic bodies was significantly enhanced. The amounts of lactate dehydrogenase, alanine aminotransferase, aspartate aminotransferase, creatinine and urea were significantly increased in serum obtained from animals exposed to hepatic IR.CONCLUSION: Inflammation and subsequent apoptotic cell death were the most important changes in early-stage hepatic reperfusion injury, and the number of apoptotic bodies increased with time of reperfusion. | Hossein Ali Arab Farhang Sasani Mohammad Hossein Rafiee Ahmad Fatemi Abbas Javaheri | 2009 | World Journal of Gastroenterology2009，15，16： | 16 |
| 9 | Tree-Temperature Monitoring for Frost Protection of Orchards in Semi-Arid Regions Using Sprinkler Irrigation显示文摘Automated over-tree sprinkler irrigation systems were developed and tested in two orchards located in two separate locations in southern Iran(a 0.17 ha peach orchard and a 0.24 ha orange orchard) to protect peach blossoms and orange trees leaves and fruits from low temperature damage.The experiment used a system that monitored the trees and air temperatures using two thermistors.The water application rate by the irrigation system was determined by an energy balance as implemented by the software FROSTPRO.In the peach orchard,the system was tested during three frost events during the spring of 2003 and three other events during the spring of 2004.The system successfully kept peach flowers above the critical temperature,i.e.,-4.0°C in spring 2004(control block -4.12°C,and sprinkled block +0.5°C) during all events.Similar results were obtained in the orange orchard during three frost events in the winter of 2004,during which the tree temperatures were at least 2.5°C above the critical temperature.Results from field tests show that the system can effectively protect the peach blossoms from damage.Determination done after the frost events showed a 12% blossom kill in the sprinkled blocks while in the unsprinkled control block a 41.5% blossom kill.Calculations indicated that when using variable application rates,the amount of water used can be reduced by 54.3%.Spatial distribution of minimum temperatures during the three frosts was also studied in Jahrom,Iran.Results showed a significant temperature control in the experimental block,especially in the central part of the orchard,but the block margins(about 3.6% of the total area) were at the risk of low temperature due to the wind drift effects. | Ali Asghar Ghaemi Mohammad Rafie Rafiee Ali Reza Sepaskhah | 2009 | Agricultural Sciences in China2009，8，1： | 14 |
| 10 | Nitrogen in Relation to Photosynthetic Capacity and Accumulation of Osmoprotectant and Nutrients in Brassica Genotypes Grown Under Salt Stress显示文摘Different strategies of the application of nutrients are required to overcome the adverse effects of mustard (Brassica juncea L.) in response to NaCl stress. The objective of the present study was to determine if different added levels of nitrogen (N) in growth medium could alleviate the adverse effects of salt stress on photosynthetic capacity and accumulation of osmoprotectants and nutrients. 14 days mustard seedlings of salt-sensitive (cv. Chuutki) and salt-tolerant (cv. Radha) genotypes were fed with: (i) 0 mmol L-1 NaCl + 0 mg N kg-1 sand (control), (ii) 90 mmol L-1 NaCl + 30 mg N kg-1 sand, (iii) 90 mmol L-1 NaCl + 60 mg N kg-1 sand, (iv) 90 mmol L-1 NaCl + 90 mg N kg-1 sand and (v) 90 mmol L-1 NaCl + 120 mg N kg-1 sand. Under the condition of salinity stress, N application caused a significant ameliorative effect on both genotypes with respect to growth attributes [fresh weight (FW) and dry weight (DW)] and physio-biochemical parameters [percent water content (WC), net photosynthetic rate (PN), stomatal conductance (gs), total chlorophyll (Chl), carbonic anhydrase (CA) activity and malondialdehyde (MDA), nitrogen (N), potassium (K) and sodium (Na) contents, and K/Na ratio] and yield attributes (number of pods/plant, seeds/pod and seed yield/plant). The salt-tolerant genotype exhibited maximum value for growth, physio-biochemical and yield attributes at 60 mg N kg-1 sand than that of salt-sensitive genotype. These results suggest that application of N may ameliorate most of the attributes and prove to be a physiological remedy to increase the tolerance against the ill effects of salt stress in Brassicas. | Manzer H Siddiqui Firoz Mohammad M Nasir Khan Mohamed H Al-Whaibi Ali H A Bahkali | 2010 | Agricultural Sciences in China2010，9，5： | 14 |
| 11 | Microstructural evolution,mechanical properties,and corrosion resistance of a heat-treated Mg alloy for the bio-medical application显示文摘During the recent years,some Mg based alloys have extensively been considered as a new generation of degradable and absorbable bio-medical materials.In this work,the Mg-2Zn-1Gd-1Ca(wt%)alloy as a new metallic bio-material was produced by the casting process followed by the heat treatment.The samples of the alloy were solution treated at temperatures of 500,550,and 600°C and then quench aged at temperatures of 125,150,and 175°C.The results of SEM-EDS examinations indicated that the alloy microstructure consists ofα-Mg matrix and the Ca_(2)Mg_(6)Zn_(3)and Mg_(3)Gd_(2)Zn_(3)secondary phases.With regard to the results of Vickers hardness test,the temperatures of 500°C and 150°C were selected as the optimum solutionizing and aging temperatures,respectively.Moreover,the dissolution of casting precipitates and production of lattice distortion occurring after the solution treatment led to the reduction in ultimate shear strength up to 21%.But,the precipitation hardening and morphological changes taking place during the aging treatment improved the ultimate shear strength up to 32%.Furthermore,the results of electro-chemical and weight-loss measurements in a simulated body fluid indicated that the heat-treated alloy is a promising candidate for the Mg based alloys recently considered for the bio-medical applications. | Mohammad Janbozorgi Kimia Karimi Taheri Ali Karimi Taheri | 2019 | Journal of Magnesium and Alloys2019，7，1： | 14 |
| 12 | Sublethal effects of hexaflumuron on development and reproduction of the diamondback moth, Plutella xylostella (Lepidoptera: Yponomeutidae)显示文摘在 10% 致命的集中(LC10 ) 和在开发和有菱形斑纹的蛾的繁殖参数的 LC25 的 hexaflumuron 的效果, Plutella xylostella (Linnaeus, 1753 )(Lep:Yponomeutidae ) 被调查。估计的 LC50, LC10 和 P 的第三个中间形态幼虫上的 hexaflumuron 的叶剧降生物鉴定的 LC25 价值。xylostella 分别地是 1.48, 0.59 和 0.91 mg/L。Hexaflumuron 减少了在在尚不致命的集中的父母产生,但是在后代产生的蛹的重量,这效果没被观察。尚不致命的集中增加了鸡蛋,第一和第二幼虫的中间形态和蛹发展时间和成年人的弄短的寿命,但是没改变第三和第四幼虫的中间形态和蛹前发展时期。另外,女性的肥沃显著地减少了,但是处理和控制的 hatchability 是类似的。成年人前阶段的幸存率在 LC25 集中显著地衰退了。象繁殖的率(R0 ) 和尚不致命的集中的增加的内在的率那样的繁殖参数与控制相比是显著地更低的,但是在 LC10 集中的粗野繁殖率(GRR ) 被增加,它能是 hormoligosis。另外, hexaflumuron 显著地增加了双倍工资(Dt ) 。我们断定 hexaflumuron 的尚不致命的效果可能在 P 的人口动力学上展出重要效果。xylostella。 | Mohammad Mahmoudvand Habib Abbasipour Aziz Sheikhi Garjan Ali Reza Bandani | 2011 | Insect Science2011，18，6： | 13 |
| 13 | Chest injury in victims of Bam earthquake显示文摘客观:为了分析损伤的数据,有在欺骗的地震的胸的损害的病人为更好在主要地震理解胸的损害的类型和后果承认了到医药科学(弦音器) 的德黑兰大学的医院。方法:登记 6 的 AfterBam 地震。5 在 Richter 上可伸缩, 526 个损伤病人进入弦音器的医院。在之中“他们, 53 个病人支撑了胸的损害。结果:这个组由 21females (39.6%) 和 32 男性(60.4%) 组成。十五个病人(28.3%) 孤立胸损害。Ribfracture (36.4%) 是在我们的病人的最普通的损害, haemo/pneumothorax (25.5%) 列在后面。表面的损害是最普通的伴随损害。有胸损害的多重损伤的病人与孤立的胸损害(P=0.003 ) 有更高的损害严厉分数(ISS ) 对病人。结论:胸墙损害和 haemo/ 气胸在地震的幸存牺牲品包括损害的一个可观的数字。因而,这些病人的多数能与观察或试管 thoracostomy 被对待。我们应该训练并且装备健康工人和救援队的成员在这块地里对待并且设法这些病人。 | Seyed Mohammad Ghodsi Moosa Zargar Ali Khaji Mojgan Karbakhsh | 2006 | Chinese Journal of Traumatology2006，9，6： | 13 |
| 14 | Ankylosing spondylitis: A state of the art factual backbone显示文摘Ankylosing spondylitis(AS) is a chronic inflammatory disease that affects 1% of the general population. As one of the most severe types of spondyloarthropathy, AS affects the spinal vertebrae and sacroiliac joints, causing debilitating pain and loss of mobility. The goal of this review is to provide an overview of AS, from the pathophysiological changes that occur as the disease progresses, to genetic factors that are involved with its onset. Considering the high prevalence in the population, and the debilitating life changes that occur as a result of the disease, a strong emphasis is placed on the diagnostic imaging methods that are used to detect this condition, as well as several treatment methods that could improve the health of individuals diagnosed with AS. | Mohammad Ghasemi-rad Hosam Attaya Emal Lesha Andrea Vegh Tooraj Maleki-Miandoab Emad Nosair Nariman Sepehrvand Ali Davarian Hamid Rajebi Abdolghader Pakniat Seyed Amirhossein Fazeli Afshin Mohammadi | 2015 | World Journal of Radiology2015，7，9： | 13 |
| 15 | Computational fluid dynamics(CFD) simulation of effect of baffles on separation in mixer settler显示文摘The main ideas in the development of the solvent extraction mixer settler focused on achieving clean phase separation,minimizing the loss of the reagents and decreasing the surface area of the settlers.The role of baffles in a mechanically agitated vessel is to ensure even distribution,reduce settler turbulence,promote the stability of power drawn by the impeller and to prevent swirling and vortexing of liquid,thus,greatly improving the mixing of liquid.The insertion of the appropriate number of baffles clearly improves the extent of liquid mixing.However,excessive baffling would interrupt liquid mixing and lengthen the mixing time.Computational fluid dynamics(CFD) provides a tool for determining detailed information on fluid flow(hydrodynamics) which is necessary for modeling subprocesses in mixer settler.A total of 54 final CFD runs were carried out representing different combinations of variables like number of baffles,density and impeller speed.CFD data shows that amount of separation increases with increasing baffles number and decreasing impeller speed. | Mohsen Ostad Shabani Ali Mazahery Mehdi Alizadeh Ali Asghar Tofigh Mohammad Reza Rahimipour Mansour Razavi Alireza Kolahi | 2012 | International Journal of Mining Science and Technology2012，22，5： | 12 |
| 16 | Critical role of SDF-1/CXCR4 signaling pathway in stem cell homing in the deafened rat cochlea after acoustic trauma显示文摘Previous animal studies have shown that stromal cell-derived factor-1(SDF-1)/CXC chemokine receptor-4(CXCR4) signaling pathway plays an important role in the targeted migration of bone marrow-derived mesenchymal stem cells(BMSCs) to the injured area. In the present study, we aimed to investigate the potential role of chemotactic SDF-1/CXCR4 signaling pathway in the homing of transplanted BMSCs to the injured cochlea after noise-induced hearing loss(NIHL) in a rat model. White noise exposure(110 d B) paradigm was used for hearing loss induction in male rats for 6 hours in 5 days. Distortion-product otoacoustic emission(DPOAE) responses were recorded before the experiment and post noise exposure. Hoechst 33342-labeled BMSCs and CXCR4 antagonist(AMD3100)-treated BMSCs were injected into the rat cochlea through the round window. SDF-1 protein expression in the cochlear tissue was assayed using western blot assay. The number of labeled BMSCs reaching the endolymph was determined after 24 hours. SDF-1 was significantly increased in the cochlear tissue of rats in the noise exposure group than in the control group. The number of Hoechst 33342-labeled BMSCs reaching the endolymph of the cochlea was significantly smaller in the AMD3100-treated BMSCs group than in the normal BMSCs group. Our present findings suggest that the SDF-1/CXCR4 signaling pathway has a critical role in BMSCs migration to the injured cochlea in a rat model of noise-induced hearing loss. | Ali Asghar Peyvandi Navid Ahmady Roozbahany Hassan Peyvandi Hojjat-Allah Abbaszadeh Niloofar Majdinasab Mohammad Faridan Somayeh Niknazar | 2018 | Neural Regeneration Research2018，13，1： | 11 |
| 17 | Predictive value and main determinants of abnormal features of intraoperative cholangiography during cholecystectomy显示文摘BACKGROUND:The major issue with intraoperative cholangiography (IOC) is whether its diagnostic accuracy for common bile duct (CBD) stones matches that of other diagnostic procedures,and thus,whether it will become a routine diagnostic procedure.The current study aimed to address the main determinants of CBD stone diagnosis in IOC among an Iranian population.METHODS:In a retrospective review database-based study conducted in Taleghani Hospital in Tehran between 2006 and 2008,baseline data and perioperative information of 2060 patients (male to female ratio 542:1518,mean age 53.7 years) who were candidates for cholecystectomy and underwent concomitant IOC for confirming CBD stones were reviewed.The predictive power of this procedure for diagnosis of abnormal biliary ducts with the focus on biliary stones was determined.RESULTS:Overall mortality and morbidity following cholecystectomy in the study population were 0.6% and 2.6%,respectively.Both early mortality and morbidity due to cholecystectomy were higher in male than female.The prevalence of CBD stones in IOC was 3.4% (5.2% in male and 2.8% in female,P=0.008).Among those without gallstones,8.7% had CBD stones and only 3.1% had concomitant gallstones and CBD stones.The main predictors of stone appearance as an abnormal feature of IOC during cholecystectomy were:advanced age (OR=1.022,P=0.001),male gender (OR=1.498,P=0.050),history of abdominal surgery (OR=1.543,P=0.040) and preoperative endoscopic retrograde cholangiopancreatography (OR=5.400,P<0.001).CONCLUSIONS:IOC is a safe and accurate method for the assessment of bile duct anatomy and stones.Therefore,the routine use of IOC within cholecystectomy seems reasonable and is recommended. | Shahram Yousefpour Azary Heshmat Kalbasi Ali Setayesh Mirhadi Mousavi Asad Hashemi Mahsa Khodadoostan Mohammad Reza Zali Amir Houshang Mohammad Alizadeh | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，3： | 11 |
| 18 | Development of underground mine monitoring and communication system integrated ZigBee and GIS显示文摘An automated underground mine monitoring and communication system based on the integration of new technologies is introduced to promote safety and health,operational management and cost-effectiveness.The proposed system integration considering Wireless Sensor Network(WSN) assisted Geographic Information System(GIS) enables to monitor and control underground mining applications from surface office.Based on the capabilities of WSNs,ZigBee network is adapted for near real-time monitoring,ventilation system control and emergency communication in underground mine.ZigBee nodes were developed to sense environmental attributes such as temperature,humidity and gases concentration;switching ON and OFF ventilation fans;and texting emergency messages.A trigger action plan for monitored attributes above normal and threshold value limits is programmed in the surface GIS management server.It is designed to turn the auxiliary fans on remotely or automatically in orange condition and sending evacuation messages for underground miners in unsafe(red) condition.Multi-users operation and 3D visualisations are other successful achievements of the proposed system for the underground monitoring and communication. | Moridi Mohammad Ali Kawamura Youhei Sharifzadeh Mostafa Chanda Emmanuel Knox Wagner Markus Jang Hyongdoo Okawa Hirokazu | 2015 | International Journal of Mining Science and Technology2015，25，5： | 11 |
| 19 | Therapeutic potential of flavonoids in inflammatory bowel disease: A comprehensive review显示文摘The inflammatory process plays a central role in the development and progression of numerous pathological situations,such as inflammatory bowel disease(IBD),autoimmune and neurodegenerative diseases,metabolic syndrome,and cardiovascular disorders. IBDs involve inflammation of the gastrointestinal area and mainly comprise Crohn's disease(CD) and ulcerative colitis(UC). Both pathological situations usually involve recurring or bloody diarrhea,pain,fatigue and weight loss. There is at present no pharmacological cure for CD or UC. However,surgery may be curative for UC patients. The prescribed treatment aims to ameliorate the symptoms and prevent and/or delay new painful episodes. Flavonoid compounds are a large family of hydroxylated polyphenolic molecules abundant in plants,including vegetables and fruits which are the major dietary sources of these compounds for humans,together with wine and tea. Flavonoids are becoming very popular because they have many health-promoting and disease-preventive effects. Most interest has been directed towards the antioxidant activity of flavonoids,evidencing a remarkable free-radical scavenging capacity. However,accumulating evidence suggests that flavonoids have many other biological properties,including anti-inflammatory,antiviral,anticancer,and neuroprotective activities through different mechanisms of action. The present review analyzes the available data about the different types of flavonoids and their potential effectiveness as adjuvant therapy of IBDs. | Ali Salaritabar Behrad Darvishi Farzaneh Hadjiakhoondi Azadeh Manayi Antoni Sureda Seyed Fazel Nabavi Leo R Fitzpatrick Seyed Mohammad Nabavi Anupam Bishayee | 2017 | World Journal of Gastroenterology2017，23，28： | 10 |
| 20 | A Novel γ-Alumina Supported Fe-Mo Bimetallic Catalyst for Reverse Water Gas Shift Reaction显示文摘在反向的水气体,移动(RWGS ) 反应 CO2 被变换成能接着被用来生产象甲醇那样的有益的化学药品的公司。在现在的学习, Mo/Al2O3, Fe/Al2O3 和 Fe-Mo/Al2O3,催化剂是用受精方法的 synthesised。催化剂的结构用 X 光检查衍射(XRD ) 被学习, Brunauer-Emmett-Teller (赌注) 方法,诱导地联合的血浆原子排放分光计(ICP-AES ) ,温度规划了减小(H2-TPR ) ,公司化学吸着,精力散 X 光检查(EDX ) 和扫描电子显微镜学(SEM ) 技术。所有催化剂的运动性质为 RWGS 反应在一个批反应堆被调查。结果显示在 Fe-Mo/Al2O3 催化剂的结构的那瞬间存在作为与 Fe/Al2O3 相比提高它的活动。这改进可能由于更好的 Fe 分散和 Fe 种类的更小的粒子尺寸。Fe-Mo/Al2O3 催化剂的稳定性测试在一个固定的床反应堆和高公司收益被执行因为溪流上的时间的 60 h 被表明。3 阶段在新鲜、使用的催化剂的结构被发现的 Fe2 (MoO4 ) 。TPR 结果也显示 3 分阶段执行的 Fe2 (MoO4 ) 有低 reducibility,因此, 3 显著地分阶段执行的 Fe2 (MoO4 ) 在催化剂禁止留下的 Fe 氧化物的减小,导致了 Fe-Mo/Al2O3 的高稳定性催化剂。总的来说,这研究与高公司产量作为新奇催化剂介绍 Fe-Mo/Al2O3,几乎没有副产品并且为 RWGS 反应相当稳定。 | Abolfazl Gharibi Kharaji Ahmad Shariati Mohammad Ali Takassi | 2013 | Chinese Journal of Chemical Engineering2013，21，9： | 10 |
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