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您的检索式：作者名="Mingfang Pu"
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| 1 | Soil salinization research in China: Advances and prospects显示文摘与气候变化的进展引起的环境恶化,土壤 salinization 是一个严重、成长的全球问题。当前,大约 7% 世界陆地表面被 salinization 威胁。中国是其土壤被这个问题严重地影响的一个国家,它由于它的广泛的区域,并且宽分发形成严肃的威胁到地区性的农业开发。在这评论,我们在过去的 70 年在中国为土壤 salinization 研究总结框架,估计存在的软弱在两个研究国内、国际的上下文,加亮趋势并且给关于在过去的 30 年的盐的土壤的全球研究的调查结果调音,并且为关于盐的土壤的未来研究建议六个主要领域和方向。 | LI Jianguo PU Lijie HAN Mingfang ZHU Ming ZHANG Runsen XIANG Yangzhou | 2014 | Journal of Geographical Sciences2014，24，5： | 90 |
| 2 | Characterization of bacteriophage BUCT631 lytic for K1 Klebsiella pneumoniae and its therapeutic efficacy in Galleria mellonella larvae显示文摘Severe infections caused by multidrug-resistant Klebsiella pneumoniae(K.pneumoniae)highlight the need for new therapeutics with activity against this pathogen.Phage therapy is an alternative treatment approach for multidrug-resistant K.pneumoniae infections.Here,we report a novel bacteriophage(phage)BUCT631 that can specifically lyse capsule-type K1 K.pneumoniae.Physiological characterization revealed that phage BUCT631 could rapidly adsorb to the surface of K.pneumoniae and form an obvious halo ring,and it had relatively favorable thermal stability(4–50C)and pH tolerance(pH?4–12).In addition,the optimal multiplicity of infection(MOI)of phage BUCT631 was 0.01,and the burst size was approximately 303 PFU/cell.Genomic analysis showed that phage BUCT631 has double-stranded DNA(total length of 44,812 bp)with a G t C content of 54.1%,and the genome contains 57 open reading frames(ORFs)and no virulence or antibiotic resistance related genes.Based on phylogenetic analysis,phage BUCT631 could be assigned to a new species in the genus Drulisvirus of the subfamily Slopekvirinae.In addition,phage BUCT631 could quickly inhibit the growth of K.pneumoniae within 2 h in vitro and significantly elevated the survival rate of K.pneumoniae infected Galleria mellonella larvae from 10%to 90%in vivo.These studies suggest that phage BUCT631 has promising potential for development as a safe alternative for control and treatment of multidrug-resistant K.pneumoniae infection. | Pengjun Han Mingfang Pu Yahao Li Huahao Fan Yigang Tong | 2023 | Virologica Sinica2023，38，5： | 0 |
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