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| 1 | Current status of ultrasound-guided surgery in the treatment of breast cancer显示文摘The primary goal of breast-conserving surgery(BCS) is to obtain tumour-free resection margins. Margins positive or focally positive for tumour cells are associated with a high risk of local recurrence, and in the case of tumour-positive margins, re-excision or even mastectomy are sometimes needed to achieve definite clear margins. Unfortunately, tumour-involved margins and re-excisions after lumpectomy are still reported in up to 40% of patients and additionally, unnecessary large excision volumes are described. A secondary goal of BCS is the cosmetic outcome and one of the main determinants of worse cosmetic outcome is a large excision volume. Up to 30% of unsatisfied cosm-etic outcome is reported. Therefore, the search for better surgical techniques to improve margin status, excision volume and consequently, cosmetic outcome has continued. Nowadays, the most commonly used localization methods for BCS of non-palpable breast cancers are wire-guided localization(WGL) and radioguided localization(RGL). WGL and RGL are invasive procedures that need to be performed pre-operatively with technical and scheduling difficulties. For palpable breast cancer, tumour excision is usually guided by tactile skills of the surgeon performing 'blind' surgery. One of the surgical techniques pursuing the aims of radicality and small excision volumes includes intraoperative ultrasound(IOUS). The best evidence available demonstrates benefits of IOUS with a significantly high proportion of negative margins compared with other localization techniques in palpable and non-palpable breast cancer. Additionally, IOUS is non-invasive, easy to learn and can centralize the tumour in the excised specimen with low amount of healthy breast tissuebeing excised. This could lead to better cosmetic results of BCS. Despite the advantages of IOUS, only a small amount of surgeons are performing this technique. This review aims to highlight the position of ultrasoundguided surgery for malignant breast tumours in the search for better oncological and cosmetic outcomes. | José H Volders Max H Haloua Nicole MA Krekel Sybren Meijer Petrousjka M van den Tol | 2016 | World Journal of Clinical Oncology2016，7，1： | 6 |
| 2 | Carbonatites and Alkaline Igneous Rocks in Post-Collisional Settings:Storehouses of Rare Earth Elements显示文摘The rare earth elements(REE)are critical raw materials for much of modern technology,particularly renewable energy infrastructure and electric vehicles that are vital for the energy transition.Many of the world's largest REE deposits occur in alkaline rocks and carbonatites,which are found in intracontinental,rift-related settings,and also in syn-to post-collisional settings.Post-collisional settings host significant REE deposits,such as those of the Mianning-Dechang belt in China.This paper reviews REE mineralization in syn-to post-collisional alkaline-carbonatite complexes worldwide,in order to demonstrate some of the key physical and chemical features of these deposits.We use three examples,in Scotland,Namibia,and Turkey,to illustrate the structure of these systems.We review published geochemical data and use these to build up a broad model for the REE mineral system in post-collisional alkaline-carbonatite complexes.It is evident that immiscibility of carbonate-rich magmas and fluids plays an important part in generating mineralization in these settings,with REE,Ba and F partitioning into the carbonate-rich phase.The most significant REE mineralization in post-collisional alkaline-carbonatite complexes occurs in shallow-level,carbothermal or carbonatite intrusions,but deeper carbonatite bodies and associated alteration zones may also have REE enrichment. | Kathryn M.Goodenough Eimear A.Deady Charles D.Beard Sam Broom-Fendley Holly ALElliott Frederick van den Berg HüseyinÖztürk | 2021 | Journal of Earth Science2021，32，6： | 2 |
| 3 | Submicron and ultrafine grained hardmetals for microdrills and metal cutting inserts显示文摘 | G Gille B Szesny K Dreyer H van den Berg J Schmidt T Gestrich G Leitner | 2002 | International Journal of Refractory Metals and Hard Materials2002，，1： | 2 |
| 4 | Stability of oriented Silicalite-1 films in view of zeolite membrane preparation 显示文摘 | Den Exter M J Van Bekkum H Rijn C J M | 1997 | Zeolites1997，19，： | 1 |
| 5 | eal-time PCR assay for the identification of Thrips palmi显示文摘 | KOX L F F van den BELD H E ZIJLSTRA C | 2005 | Bulletin OEPP/EPPO Bulletin2005，35，： | 1 |
| 6 | Organic carbon in soils of the world显示文摘 | ESWARRAN H E VAN DEN BERG E V REICH P | 1993 | Soil Science Society of America Journal1993，57，： | 1 |
| 7 | Toll-like receptor 2 controls expansion and function of regulatory T cells显示文摘 | Sutmuller R P den Brok M H Kramer M | 2006 | J Clin Invest2006，116，2： | 1 |
| 8 | Effect of chemical modifications on peptide fragmentation behavior upon electron transfer induced dissociation显示文摘 | HENNRICH M L BOERSEMA P J VAN DEN TOORN H | 2009 | Anal Chem2009，81，18： | 1 |
| 9 | Cryopreservation of boar semen with small between-boar variation of post-thaw sperm survival显示文摘 | Woelders H Den Besten | 1993 | Cryobiology1993，30，： | 1 |
| 10 | Near-net-shaping in the hardmetal industry 显示文摘 | K R?diger H van den Berg K Dreyer | 2002 | Refractory Metals & Hard Materials2002，18，23： | 1 |
| 11 | Intima-media thickness of peripheral arteries in asymptomatic cigarette smokers显示文摘 | van den Berkmortel FW Smilde TJ Wollersheim H | 2000 | Atherosclerosis2000，150，： | 1 |
| 12 | Heavy cycles in weighted graphs显示文摘 | Bondy J A Broersma H J Heuvel J van den | 2002 | Discuss Math Graph Theory2002，22，： | 1 |
| 13 | Prediction of alluvial channel pattern of perennial rivers显示文摘 | Van den Berg J H | 1995 | Geomorphology1995，12，4： | 1 |
| 14 | Oxidative stress induces the expression of Fas and Fas ligand and apoptosis in murine intestinal epithelialcells 显示文摘 | Denning TL Takaishi H Crowe SE | 2002 | Free Radic Biol Med2002，33，12： | 1 |
| 15 | Accuracy of abnormal karyotypes after the analysis of both short and long term culture of chofionic villi显示文摘 | van den Berg C Van Op staiD Brandenberg H | 2000 | Prenat Diagn2000，20，12： | 1 |
| 16 | Organic car- bon in soils of the world显示文摘 | ESWARAN H Van den Berg E Reich P | 1993 | Soil Sei Soc Amer J1993，57，： | 1 |
| 17 | Heart failure and incident late-life depression 显示文摘 | Luijendijk HJ Tiemeier H van den Berg JF | 2010 | J Am Geriatr Soc2010，58，8： | 1 |
| 18 | Chemoradiation therapy in non-small cell lung cancer显示文摘 | Baas P Belderbos JS van den H euvel M | 2011 | Curr Opin Oncol2011，23，2： | 1 |
| 19 | Regulatory role of p27kip1 in the mouse and human testis显示文摘 | Beumer TL Kiyokawa H Roepers-Gajadien HL van den Bos LA Lock TM Gademan IS Rutgers DH Koff A de Rooij DG | | 0，，： | 1 |
| 20 | CRF and stress in fish显示文摘 | Flik G Klaren P H van den Burg E H | 2006 | General and Comparative Endocrinology2006，146，1： | 1 |
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