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| 1 | Decoding altitude-activated regulatory mechanisms occurring during apple peel ripening显示文摘Apple(Malus domestica Borkh)is an important fruit crop cultivated in a broad range of environmental conditions.Apple fruit ripening is a physiological process,whose molecular regulatory network response to different environments is still not sufficiently investigated and this is particularly true of the peel tissue.In this study,the influence of environmental conditions associated with low(20 m)and high(750 m)altitude on peel tissue ripening was assessed by physiological measurements combined with metabolomic and proteomic analyses during apple fruit development and ripening.Although apple fruit ripening was itself not affected by the different environmental conditions,several key color parameters,such as redness and color index,were notably induced by high altitude.Consistent with this observation,increased levels of anthocyanin and other phenolic compounds,including cyanidin-3-O-galactoside,quercetin-3-O-rhamnoside,quercetin-3-O-rutinoside,and chlorogenic acid were identified in the peel of apple grown at high altitude.Moreover,the high-altitude environment was characterized by elevated abundance of various carbohydrates(e.g.,arabinose,xylose,and sucrose)but decreased levels of glutamic acid and several related proteins,such as glycine hydroxymethyltransferase and glutamate–glyoxylate aminotransferase.Other processes affected by high altitude were the TCA cycle,the synthesis of oxidative/defense enzymes,and the accumulation of photosynthetic proteins.From the obtained data we were able to construct a metabolite-protein network depicting the impact of altitude on peel ripening.The combined analyses presented here provide new insights into physiological processes linking apple peel ripening with the prevailing environmental conditions. | Evangelos Karagiannis Michail Michailidis Georgia Tanou Federico Scossa Eirini Sarrou George Stamatakis Martina Samiotaki Stefan Martens Alisdair R.Fernie Athanassios Molassiotis | 2020 | Horticulture Research2020，7，1： | 3 |
| 2 | Manufacturing of cylindrical gears by generating cutting processes: A critical synthesis of analysis methods显示文摘 | K.-D. Bouzakis E. Lili N. Michailidis O. Friderikos | 2008 | CIRP Annals - Manufacturing Technology2008，，2： | 2 |
| 3 | PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain显示文摘 | Rohacs T Lopes C M Michailidis I Logothetis D E | 2005 | Nat Neurosci2005，8，： | 1 |
| 4 | X-ray,EPMA,and oxygen iso- tope study of vermiculitized micas in the ultramafic rocks at Askos, Macedonia, Greece 显示文摘 | Tsirambides A Michailidis K | 1999 | Applied Clay Science1999，14，： | 1 |
| 5 | Localvote decision fusion for target detection in wirelesssensor networks显示文摘 | KATENKA N LEVINA E MICHAILIDIS G | 2008 | IEEE Transactions on SignalProcessing2008，56，1： | 1 |
| 6 | Effects of sexual maturation and Salmonella infection on the expression of Toll-like receptors in the chicken vagina显示文摘 | Michailidis G Theodoridis A Avdi M | | 0，，： | 1 |
| 7 | Processor array architectures for flexible approximate string matching 显示文摘 | Michailidis P D Margaritis K G | 2008 | Journal of Systems Architecture2008，54，12： | 1 |
| 8 | Manu- {acturing o{ Cylindrical Gears by Generating Cut- ting Processes: A Critical Synthesis of Analysis Methods显示文摘 | Bouzaki K D Lili E Michailidis N | 2008 | CIRP Annals-manufacturing Tech- nology2008，57，2： | 1 |
| 9 | Nuchal teanslucency measurement and pregnancy outcome in karyotypically normal fetuses 显示文摘 | Michailidis GD Economides DL | 2001 | Ultrasound Obstet Gyneco12001，17，2： | 1 |
| 10 | A Co-training algorithm for multi-view data with applications in data fusion 显示文摘 | CULP M MICHAILIDIS G | 2009 | Ghemometries2009，23，8： | 1 |
| 11 | Antiviral ther-apies :focus on hepatitis B reverse transcriptase 显示文摘 | MICHAILIDIS E KIRBY KA HACHIYA A | 2012 | Int J Bio-chem Cell fi2012，44，7： | 1 |
| 12 | Expression of avian β-defensins and Toll-like receptor genes in the rooster epididymis during growth and Salmonella infection显示文摘 | M. Anastasiadou M. Avdi G. Michailidis | 2013 | Animal Reproduction Science2013，，： | 1 |
| 13 | Failure mechanisms of physically vapour deposited coated hardmetal cutting inserts in turn- ing显示文摘 | BOUZAKIS K D MICHAILIDIS N VIDAKIS N | 2001 | Wear2001，248，12： | 1 |
| 14 | An iterative algorithm for extending learners to a semi-supervised setting显示文摘 | M Culp G Michailidis | 2008 | Journal of Computational Graphics and Statistics2008，17，3： | 1 |
| 15 | Dif-ferential protein expression profiling by iTRAQ-2DLC-MS/MS of lung cancer cells undergoing epithelial-mesen-chymal transition reveals a migratory/invasive phenotyPe显示文摘 | Keshamouni VG Michailidis G Grasso CS | | 0，，05： | 1 |
| 16 | Change-point estimation under adaptive sampling显示文摘 | Lan Y Banerjee M Michailidis G | 2009 | Ann Statist2009，37，： | 1 |
| 17 | Retrospective analysis of real world efficacy of angiotensin receptor blockers versus other classes of antihypertensive agents in blood pressure management显示文摘 | Petrella R Michailidis P | | 0，，09： | 1 |
| 18 | Clinical Characteristics of IRIS Syndrome in Patients with HIV and Tuberculosis显示文摘 | Michailidis C Pozniak AL Mandalia S | 2005 | Antivir Ther2005，10，3： | 1 |
| 19 | Effect on PVD coated cemented carbide inserts cutting performance of micro-blasting and lapping of their substrates 显示文摘 | Bouzakis K D Skordaris G Michailidis N | 2005 | Surface and Coatings Technology2005，200，14： | 1 |
| 20 | The inclined impact test, an efficient method to characterize coatings cohesion and adhesion properties 显示文摘 | K-D Bouzakis A Asimakopoulos N Michailidis | 2004 | Thin Solid Films2004，，： | 1 |
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