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| 1 | 1,25‐dihydroxyvitamin D3 and its nuclear receptor repress human α1(I) collagen expression and type I collagen formation显示文摘 | James J. Potter Xiaopu Liu Ayman Koteish Esteban Mezey | 2013 | Liver Int2013，，5： | 2 |
| 2 | Abnormal liver chemistries as a predictor of COVID-19 severity and clinical outcomes in hospitalized patients显示文摘BACKGROUND Abnormal liver chemistries are common findings in patients with Coronavirus Disease 2019(COVID-19).However,the association of these abnormalities with the severity of COVID-19 and clinical outcomes is poorly understood AIM We aimed to assess the prevalence of elevated liver chemistries in hospitalized patients with COVID-19 and compare the serum liver chemistries to predict the severity and in-hospital mortality.METHODS This retrospective,observational study included 3380 patients with COVID-19 who were hospitalized in the Johns Hopkins Health System(Baltimore,MD,United States).Demographic data,clinical characteristics,laboratory findings,treatment measures,and outcome data were collected.Cox regression modeling was used to explore variables associated with abnormal liver chemistries on admission with disease severity and prognosis RESULTS A total of 2698(70.4%)had abnormal alanine aminotransferase(ALT)at the time of admission.Other more prevalent abnormal liver chemistries were aspartate aminotransferase(AST)(44.4%),alkaline phosphatase(ALP)(16.1%),and total bilirubin(T-Bil)(5.9%).Factors associated with liver injury were older age,Asian ethnicity,other race,being overweight,and obesity.Higher ALT,AST,T-Bil,and ALP levels were more commonly associated with disease severity.Multivariable adjusted Cox regression analysis revealed that abnormal AST and T-Bil were associated with the highest mortality risk than other liver injury indicators during hospitalization.Abnormal AST,T-Bil,and ALP were associated with a need for vasopressor drugs,whereas higher levels of AST,T-Bil,and a decreased albumin levels were associated with mechanical ventilation CONCLUSION Abnormal liver chemistries are common at the time of hospital admission in COVID-19 patients and can be closely related to the patient’s severity and prognosis.Elevated liver chemistries,specifically ALT,AST,ALP,and T-Bil levels,can be used to stratify risk and predict the need for advanced therapies in these patients. | Arunkumar Krishnan Laura Prichett Xueting Tao Saleh A Alqahtani James P Hamilton Esteban Mezey Alexandra T Strauss Ahyoung Kim James J Potter Po-Hung Chen Tinsay A Woreta | 2022 | World Journal of Gastroenterology2022，28，5： | 2 |
| 3 | Turning blood into brain:cells bearing neuronal antigens generated in vivo from bone marrow显示文摘 | Mezey E Chandross KJ Harta G | | 0，，： | 2 |
| 4 | Turning blood into brain:cells bearing neuronal antigens generated in vivo from bone marrow显示文摘 | Chandross KJ Harta G | 2000 | Science2000，290，5497： | 1 |
| 5 | Transplanted bone marrow generates new neurons in human brains显示文摘 | Mezey E Key S Vogelsang G | 2003 | Proc Natl Aead Sci USA2003，100，： | 1 |
| 6 | Turning blood into brain: cells bearing neuronal antigens generated in vivo from bone marrow显示文摘 | Mezey E Chandross KJ Harta G | 2000 | Science2000，290，5497： | 1 |
| 7 | Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice 显示文摘 | glitis MA Mezey E | 1997 | Proc Natl Acad Sci USA1997，94，： | 1 |
| 8 | Modulation of bone marrow stromal cell functions in infectious diseases by toll-like receptor ligands显示文摘 | Krisztian Nemeth Balazs Mayer Eva Mezey | 2010 | Journal of Molecular Medicine2010，，1： | 1 |
| 9 | Analyses of magnetic-field peak-exposure summary measures显示文摘 | Mezei G Bracken TD Senior R | 2006 | J Expo Sci Environ Epidemiol2006，16，6： | 1 |
| 10 | Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice显示文摘 | Mezey E | 1997 | Proc Natl Acad Sci USA1997，94，8： | 1 |
| 11 | The nurse competence in aging initiative: encouraging expertise in the care of older adults显示文摘 | Stierle L J Mezey M Schumann M J | 2006 | Am J Nurs2006，106，9： | 1 |
| 12 | Trans differentiation of rat hepat- ic stellate cells resuhs in leptin expression 显示文摘 | Potter JJ Womack L Mezey E | 1998 | Chem Biophys Res Commun1998，244，1： | 1 |
| 13 | influence of leptin in the development of hepatic fibrosis produced in mice by Schistosoma mansoni infection and b Chronic tetrachlorirde administration显示文摘 | Potter JJ Rennie Tankesley L Mezey E | 2003 | J Hepatol2003，38，： | 1 |
| 14 | Evaluation of mobile services and substantial a- doption factors with Analytic Hierarchy Process (AHP) 显示文摘 | Nikou S Mezei J | 2013 | Tele- communications Policy2013，37，10： | 1 |
| 15 | Turning blood into brain:cells bearing neuronal antigens generated in vivo from bone marrow显示文摘 | Mezey E Chandross KJ Harta G | | 0，，5497： | 1 |
| 16 | Hematopoietic cells differentiate into both maicroglia and macroglia in the brains of adultmice 显示文摘 | Eglitis MA Mezey E | 1997 | Proc Natl Acad Sci USA1997，94，23： | 1 |
| 17 | Free-energy simulation studies on the hydration of tetramethylurea and tetramethylthiourea显示文摘 | MEZEI M JANCSO G | 1995 | Chemical Physics Letters1995，239，46： | 1 |
| 18 | Liposome ocular delivery systems显示文摘 | MEISNER D MEZEI M | 1995 | Adv Drag Deliv Rev1995，16，1： | 1 |
| 19 | Chorionic vilus sampling:a 15-year experience显示文摘 | Beke A Mezei G | 2002 | Fetal Diagn Ther2002，17，： | 1 |
| 20 | Pressure Dependence of the Atmospheric Electrolyte Cathode Glow Discharge Spectrum显示文摘 | Mezei P Cserfalvi T Janossy M | 1997 | Journal of Analytical Atomic Spectrometry1997，12，10： | 1 |
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