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1Hepatic osteodystrophy and liver cirrhosis显示文摘AIM: To investigate the correlation between hepatic osteodystrophy and osteoporosis in patients with liver cirrhosis. METHODS: Bone mineral density of the patients (n = 55) and that of the control group (n = 30) were measured by dual-energy X-ray absorptiometry. All the women in the study were premenopausal. Deoxypyridinoline, pyridinoline and urinary Ca 2+ were measured as bone destruction markers, while alkaline phosphatase (ALP), osteocalcin and insulin-like growth factor-1 (IGF-1) were measured as bone formation markers. Furthermore, interleukin-1 (IL-1), IL-6, tumor necrosis factor α (TNF-α), vitamin D3, direct bilirubin, albumin, cortisol and parathyroid hormone (PTH) levels were measured. The independent Student t test and χ 2 test were employed in comparing both groups, and the Pearson correlation test was used to determine associations. RESULTS: Comparing cirrhosis and control groups, lumbar total T-score (-1.6 ± 1.2 g/cm 2 vs -0.25 ± 1.3 g/cm 2 , P < 0.001), lumbar total Z-score (-1.2 ± 1.23 g/cm 2 vs -0.6 ± 1.3 g/cm 2 , P < 0.001), total femur T-score (-0.05 ± 1 g/cm 2 vs -0.6 ± 0.9 g/cm 2 , P = 0.003) and total femur Z-score (-0.08 ± 1.5 g/cm 2 vs 0.7 ± 0.9 g/cm 2 , P =0.003) showed significantly lower values in the cirrhosis group. Blood ALP level (109.2 ± 57 U/Lvs 62.6 ± 32.5 U/L, P < 0.001), IL-6 level (27.9 ± 51.6 pg/mL vs 3.3 ± 3.1 pg/mL, P = 0.01), TNF-α level (42.6 ± 33.2 pg/mL vs 25.3 ± 12.3 pg/mL, P = 0.007) and direct bilirubin level (0.9 ± 0.7 mg/dL vs 0.3 ± 0.2 mg/dL, P < 0.001) were significantly higher in the cirrhosis group. IGF-1 level (47.7 ± 26.2 ng/mL vs 143.4 ± 53.2 ng/mL, P < 0.001), osteocalcin level (1.05 ± 2.5 ng/mL vs 7.0 ± 13 ng/mL, P = 0.002) and 24 h urinary Ca 2+ (169.6 ± 227.2 mg/dL vs 287 ± 168.6 mg/dL, P = 0.003) were significantly lower in the cirrhosis group. Urinary deoxypyridinoline/creatinine (9.4 ± 9.9 pmol/μmol vs 8.1 ± 5.3 pmol/μmol, P = 0.51), urinary pyridinoline/creatinine (51.3 ± 66.6 pmol/μmol vs 29 ± 25.8 pmol/μmol, P = 0.08), blood IL-1 level (3.4 ± 8.8 pg/mL vs 1.6 ± 3.5 pg/mL, P = 0.29), vitamin D3 level (18.6 ± 13.3 μg/L vs 18.4 ± 8.9 μg/L, P = 0.95), cortisol level (11.1 ± 4.8 μg/dL vs 12.6 ± 4.3 μg/dL, P = 0.15) and PTH level (42.7 ± 38 μg/dL vs 34.8 ± 10.9 μg/dL,P = 0.27) were not significantly different. CONCLUSION: Hepatic osteodystrophy is an important complication encountered in patients with liver cirrhosis and all patients should be monitored for hepatic osteodystrophy.Vedat Goral Mehmet Simsek Nuriye Mete 2010World Journal of Gastroenterology2010,16,13:11
2Long-term aspirin pretreatment in the prevention of cerulein-induced acute pancreatitis in rats显示文摘AIM:To investigate the effects of long term pretreatment with low-,medium-and high-dose aspirin(acetylsalicylic acid,ASA) on a model of acute pancreatitis(AP) induced in rats.METHODS:Forty male Wistar rats were used.Three experimental groups,each consisting of eight animals,received low-(5 mg/kg per day),medium-(150 mg/kg per day) and high-dose(350 mg/kg per day) ASA in supplemented pellet chow for 100 d.Eight animals,serving as the AP-control group,and another eight,serving as reference value(RV) group,were fed with standard pellet chow for the same period.After pretreatment,AP was induced in the experimental animals by intraperitoneal administration of cerulein(2 × 50 μg/kg),while the RV group received saline in the same way.Twelve hours after the second injection,the animals were sacrificed.Pancreatic tissue and plasma samples were collected.One part of the collected pancreatic tissues was used for histopathological evaluation,and the remaining portion was homogenized.Cytokine levels [tumor necrosis factor,interleukin(IL)1β,IL-6],hemogram parameters,biochemical parameters(amylase and lipase),nuclear factor-κB,aspirin triggered lipoxins and parameters related to the antioxidant system(malondialdehyde,nitric oxide,hemeoxygenase-1,catalase and superoxide dismutase) were measured.RESULTS:Cerulein administration induced mild pancreatitis,characterized by interstitial edema(total histopathological score of 5.88 ± 0.44vs 0.25 ± 0.16,P < 0.001).Subsequent pancreatic tissue damage resulted in an increase in amylase(2829.71 ± 772.48 vs 984.57 ± 49.22 U/L,P = 0.001) and lipase(110.14 ± 75.84 U/L vs 4.71 ± 0.78 U/L,P < 0.001) in plasma,and leucocytes(6.89 ± 0.48 vs 4.36 ± 0.23,P = 0.001) in peripheral blood.Cytokines,IL-1β(18.81 ± 2.55 pg/μg vs 6.65 ± 0.24 pg/μg,P = 0.002) and IL-6(14.62 ± 1.98 pg/μg vs 9.09 ± 1.36 pg/μg,P = 0.04) in pancreatic tissue also increased.Aspirin pretreatment reduced the increase in the aforementioned parameters to a certain degree and partially improved the histopathological alterations caused by cerulein.No evidence of side effects related to chronic ASA administration(e.g.,inflammation or bleeding) was observed in the gastrointestinal tract in macroscopic and histopathological examination.CONCLUSION:Long term ASA pretreatment could prevent and/or ameliorate certain hematological,serological and histological alterations caused by ceruleininduced AP.Ibrahim Akyazi Evren Eraslan Ahmet Gülubuk Elif Ergül Ekiz Zeynep L rakli Damla Haktanir Deniz Aktaran Bala Mete zkurt Erdal Matur Mukaddes zcan 2013World Journal of Gastroenterology2013,19,19:5
3Comparison of intraperitoneal and intratesticular ozone therapy for the treatment of testicular ischemia-reperfusion injury in rats显示文摘我们在一个试验性的老鼠模型把 intratesticular 臭氧治疗的功效与 intraperitoneal 臭氧治疗作比较。为这个目的, 24 只老鼠加 intratesticular 臭氧(O 信息技术) 包括假冒操作, torsion/detorsion,加 intraperitoneal 臭氧(O-IP ) 的 torsion/detorsion,和 torsion/detorsion 被划分成四个组。O-IP 臭氧组收到了臭氧的 4 mg kg −1 intraperitoneal 注射,并且 O 信息技术组 epididymally 收到了一样的注射。在在 detorsion 以后的 4 h,老鼠被牺牲, orchiectomy 材料组织病理学说地被估计。在到 Sertoli 房间的生精的小管和损坏的精子发生组织病理学说地用 Johnsen 得分系统在睾丸被评估。我 -- 在睾丸织物的 NOS 和电子 NOS 活动也被评估。Torsion-detorsion 引起了一个减少的 Johnsen 分数并且增加了 spermatogonial 和 Sertoli 房间的 apoptosis。阻止的臭氧注射在 Johnsen 分数和 i 增加 -- NOS 水平。O-IP 组的电子 NOS 水平比 O-IP 组,和 i 的显著地低 --O 信息技术组的 NOS 水平比 O-IP 组的显著地低。本地臭氧治疗是比在改进 IRI 相关的阴囊的扭转的全身的臭氧治疗更有效的。我们的学习是第一证明臭氧治疗的 intratesticular 实现的功效比 intraperitoneal 臭氧治疗的高。Fatih Mete Huseyin Tarhan Orcun Celik Ilker Akarken Kamil Vural Rahmi Gokhan Ekin Isil Aydemir Yusuf Ozlem Ilbey 2017Asian Journal of Andrology2017,19,1:5
4Feature Selection for Malware Detection on the Android Platform Based on Differences of IDF Values显示文摘Android is the mobile operating system most frequently targeted by malware in the smartphone ecosystem,with a market share significantly higher than its competitors and a much larger total number of applications.Detection of malware before being published on official or unofficial application markets is critically important due to the typical end users'widespread security inadequacy.In this paper,a novel feature selection method is proposed along with an Android malware detection approach.The feature selection method proposed in this study makes use of permissions,API calls,and strings as features,which are statically extractable from the Android executables(APK files)and it can be used in a machine learning process with different algorithms to detect malware on the Android platform.A novel document frequency-based approach,namely Delta IDF,was designed and implemented for feature selection.Delta IDF was tested upon three universal benchmark datasets that contain Android malware samples and highly promising results were obtained by using several binary classification algorithms.Gokcer Peynirci Mete Eminagaoglu Korhan Karabulut 2020Journal of Computer Science & Technology2020,35,4:4
5Extensive hepatic-portal and mesenteric venous gas due to sigmoid diverticulitis显示文摘Hepatic portal venous gas is most often associated with extensive bowel necrosis due to mesenteric infarction.Mortality exceeds 75% with this condition.The most common precipitating factors include ischemia,intra-abdominal abscesses and inflammatory bowel disease.In this report,we present a 75-year-old woman with extensive hepatic portal and mesenteric venous gas due to colonic diverticulitis.She had a 10-year history of type diabetes mellitus and hypertension.She was treated by sigmoid resection and Hartmann's procedure and discharged from the hospital without any complications.Meral Sen Ayhan Akpinar Aydin Snan Mete Sisman Cenap Dener Kayihan Akin 2009World Journal of Gastroenterology2009,15,7:4
6Kefir treatment ameliorates dextran sulfate sodium-induced colitis in rats显示文摘AIM: To investigate the preventive effect of kefir on colitis induced with dextran sulfate sodium(DSS) in rats.METHODS: Twenty-four male Wistar-albino rats were randomized into four groups: normal control,kefircontrol,colitis,and kefir-colitis groups. Rats in the normal and kefir-control groups were administered tap water as drinking water for 14 d. Rats in the colitis and kefir-colitis groups were administered a 3% DSS solution as drinking water for 8-14 d to induce colitis. Rats in the kefir-control and kefir-colitis groups were administered 5 m L kefir once a day for 14 d while rats in the normal control and colitis group were administered an identical volume of the placebo(skim milk) using an orogastric feeding tube. Clinical colitis was evaluated with reference to the disease activity index(DAI),based on daily weight loss,stool consistency,and presence of bleeding in feces. Rats were sacrificed on the 15 th day,blood specimens were collected,and colon tissues were rapidly removed. Levels of myeloperoxidase(MPO),tumor necrosisfactor(TNF)-α,interleukin(IL)-10,malondialdehyde,and inducible nitric oxide synthase(i NOS) were measured in colon tissue.RESULTS: The DAI was lower in the kefir-colitis group than in the colitis group(on the 3rd and 5th days of colitis induction; P < 0.01). The DAI was also significantly higher in the colitis group between days 2 and 6 of colitis induction when compared to the normal control and kefir-control groups. The DAI was statistically higher only on the 6th day in the kefircolitis group when compared to that in the normal control groups. Increased colon weight and decreased colon length were observed in colitis-induced rats. Mean colon length in the colitis group was significantly shorter than that of the kefir-control group. Kefir treatment significantly decreased histologic colitis scores(P < 0.05). MPO activity in the colitis group was significantly higher than in the kefir-control group(P < 0.05). Kefir treatment significantly reduced the DSS colitis-induced TNF-α increase(P < 0.01). No statistically significant differences were observed among groups for IL-10 and MDA levels. Colon tissue i NOS levels in the colitis group were significantly higher than those in the control and kefir-colitis groups(P < 0.05).CONCLUSION: Kefir reduces the clinical DAI and histologic colitis scores in a DSS-induced colitis model,possibly via reduction of MPO,TNF-α,and i NOS levels.Altug Senol Mehmet Isler Recep Sutcu Mete Akin Ebru Cakir Betul M Ceyhan M Cem Kockar 2015World Journal of Gastroenterology2015,21,46:3
7Chronic constipation:Facilitator factor for development of varicocele显示文摘AIM:To evaluate the possible relationship between varicocele and chronic constipation.METHODS:Between April 2009 and May 2010,a total of 135 patients with varicocele or constipation and 120 healthy controls were evaluated.Patients were divided into two groups.In both groups detailed medical history was taken and all patients were examined physically by the same urologist and gastroenterologist.All of them were evaluated by color Doppler ultrasonography.All patients with constipation,except for the healthy controls of the second group,underwent a colonoscopy to identify the etiology of the constipation.In the first group,we determined the rate of chronic constipation in patients with varicocele and in the second group,the rate of varicocele in patients with chronic constipation.In both groups,the rate of the disease was compared with age-matched healthy controls.In the second group,the results of colonoscopies in the patients with chronic constipations were also evaluated.RESULTS:In the first group,mean age of the study and control groups were 22.9 ± 4.47 and 21.8 ± 7.21 years,respectively(P < 0.05).In the second group,mean age of the study and control groups were 52.8 ± 33.3 and 51.7 ± 54.3 years,respectively(P < 0.05).In the first group,chronic constipation was observed in 8 of the 69 patients with varicocele(11.6%) and 3 out of 60 in healthy controls(5%),respectively.In this regard,there was no statistical significance between varicocele patients and the healthy control(P = 0.37).In the second group,varicocele was observed in 16 of the 66 patients with chronic constipation(24.24%) and 12 out of 60 in healthy controls(20%) respectively.Similarly,there was no statistical significance between chronic constipation and healthy controls(P = 0.72).Internal/external hemorrhoids were detected in 4 of the 16 patients with chronic constipation and varicocele,in the second group.In the remaining 50 patients with chronic constipation 9 had internal/external hemorrhoids.In this regard,there was no statistical significance between chronic constipation and healthy controls(P = 0.80).CONCLUSION:Chronic constipation may not be a major predictive factor for the development of varicocele,but it may be a facilitator factor for varicocele.Guldem Kilciler Ahmet Ali Sancaktutar Ali Avcl Mete Kilciler Engin Kaya Murat Dayanc 2011World Journal of Gastroenterology2011,17,21:3
8Differences in individual susceptibility affect the development of trigeminal neuralgia显示文摘Trigeminal neuralgia is a syndrome due to dysfunctional hyperactivity of the trigeminal nerve,and is characterized by a sudden,usually unilateral,recurrent lancinating pain arising from one or more divisions of the nerve.The most accepted pathogenetic mechanism for trigeminal neuralgia is compression of the nerve at its dorsal root entry zone or in its distal course.In this paper,we report four cases with trigeminal neuralgia due to an unknown mechanism after an intracranial intervention.The onset of trigeminal neuralgia after surgical interventions that are unrelated to the trigeminal nerve suggests that in patients with greater individual susceptibility,nerve contact with the vascular structure due to postoperative pressure and changes in cerebrospinal fluid flow may cause the onset of pain.Yusuf Kurtulus Duransoy Mesut Mete Emrah Akay Mehmet Seluki 2013Neural Regeneration Research2013,8,14:3
9GATA3和TTF-1(SPT24)的阳性和单克隆PAX8阴性扩大了甲状腺实性细胞巢的生物标志物谱显示文摘实性细胞巢(SCNs)是后腮体(ultimobranchial)残余,这种附带的微观结构在甲状腺切除标本中经常看到。SCN大体呈实性和(或)微囊模式,还有一些与甲状腺滤泡混合。组织学上,主要由伸长细胞与多边形被称为主细胞的细胞组成,后者核位于中央,核仁清楚,但细胞轮廓不规则,偶见核沟,类似鳞状细胞,但缺乏角化及细胞间桥。一些可见散在的滤泡旁C细胞。镜下SCNs分为四种类型:1型由花蕾状小的伸长型细胞构成,核椭圆形或梭形,偶见核沟;2型具有表皮样特征,可见含有丰富胞质的大多边形细胞;3型伴囊性结构,由大小不一、数量不等的SCNs细胞构成;4型由甲状腺滤泡上皮及SCNs主细胞混合而成,核呈椭圆形/梭形,核沟罕见。张仕强 方三高 Gucer H Mete O 2018临床与实验病理学杂志2018,34,11:3
10Flexible supercapacitor electrodes with vertically aligned carbon nanotubes grown on aluminum foils显示文摘In this work, vertically aligned carbon nanotubes(VACNTs) grown on aluminum foils were used as flexible supercapacitor electrodes. Aluminum foils were used as readily available, cheap and conductive substrates, and VACNTs were grown directly on these foils through chemical vapor deposition(CVD)method. Solution based ultrasonic spray pyrolysis(USP) method was used for the deposition of the CNT catalyst. Direct growth of VACNTs on aluminum foils ruled out both the internal resistance of the supercapacitor electrodes and the charge transfer resistance between the electrode and electrolyte. A specific capacitance of 2.61 m F/cm^2 at a scan rate of 800 m V/s was obtained from the fabricated electrodes, which is further improved through the bending cycles.Itir Bakis Dogru Mete Batuhan Durukan Onur Turel Husnu Emrah Unalan 2016Progress in Natural Science:Materials International2016,26,3:2
11The impact of growth, energy and financial development on the environment in China: A cointegration analysis显示文摘Abdul Jalil Mete Feridun 2010Energy Economics2010,,2:2
12Formation of air-entraining vortices at horizontal intakes without approach flow induced circulation显示文摘The aim of this experimental study is to investigate the effects of hydraulic parameters on the formation of air-entraining vortices at horizontal intake structures without approach flow induced circulation. Six intake pipes of different diameters were tested in the study. The intake pipe to be tested was horizontally mounted to the front side of a large reservoir and then for a wide range of discharges experiments were conducted and critical submergences were detected with adjustable approach channel sidewalls. Empirical equations were derived for the dimensionless critical submergence as a function of the relevant dimensionless parameters. Available data is also checked for the possible scale effect. Then, these obtained equations were compared with the similar ones in the literature which showed a quite good agreement.Mustafa GOGUS Mete KOKEN Ali BAYKARA 2016Journal of Hydrodynamics2016,28,1:2
13梭形细胞嗜酸细胞瘤和垂体颗粒细胞瘤是垂体细胞瘤的亚型(英)显示文摘垂体细胞瘤是垂体细胞(垂体后叶特化的胶质细胞)发生的肿瘤。垂体细胞有5种超微结构亚型:明细胞、暗细胞、颗粒细胞、室管膜细胞和嗜酸细胞。垂体颗粒细胞肿瘤被认为来自颗粒垂体。梭形细胞嗜酸细胞瘤被认为来自滤泡星形细胞(垂体前叶特殊的支持细胞)。最近研究显示,垂体细胞和所有3种类型肿瘤的TTF-1均阳性,滤泡星形细胞TTF-1阴性。该研究根据7例梭形细胞嗜酸细胞瘤,Mete O 许春伟 2014诊断病理学杂志2014,21,12:2
14Predisposing factors to phlebitis in pa-tients with Perpheral intravenous catheters:a descriptirestudy显示文摘Uslnsoy E Mete S 2008AANP2008,20,4:1
15Food allergy due to olive显示文摘Unsel M Ardeniz 0 Mete N 2009J Investing Allergol Clin Immunol2009,19,6:1
16Speed-sensorless estimation for induction motors using extended kalman filters显示文摘MURAT B SETA B METING 2007IEEE Transac- tions on Industrial Electronics2007,54,1:1
17Stochastic optimization of medical supply location and distribution in disaster management显示文摘Huseyin Onur Mete Zelda B Zabinsky 2010Int J Production Economics2010,126,:1
18An Investigation into Breastfeeding Characteristics of Mothers Attending Childbirth Education Classes显示文摘Samiye Mete Kerziban Yenal Hülya Okumu 2010Asian Nursing Research2010,4,4:1
19Laboratory studies of wind stress over surface waves显示文摘METE B U Z MARK A DONELAN 2002Boundary Layer Meteorology2002,102,2:1
20Stamping process design using FEA in conjunction with orthogonal regression显示文摘Mehmet Firat Osman H. Mete Umit Kocabicak Murat Ozsoy 2010Finite Elements in Analysis & Design2010,,11:1
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