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94篇 您的检索式：作者名="Meisner A"

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	题名	作者	年代	出处	被引量
1	ATG16L1 and NOD2 polymorphisms enhance phagocytosis in monocytes of Crohn's disease patients显示文摘AIM:To investigate if the presence of relevant genetic polymorphisms has effect on the effectual clearance of bacteria by monocytes and granulocytes in patients with Crohn’s disease(CD).METHODS:In this study,we assessed the differential responses in phagocytosis by measuring the phagocytic activity and the percentage of active phagocytic monocytes and granulocytes in inflammatory bowel disease patients as well as healthy controls.As both autophagy related like 1(ATG16L1)and immunityrelated guanosine triphosphatase gene are autophagy genes associated with CD and more recently nucleo-tide-binding ligomerization domain-containing protein2(NOD2)has been identified as a potent inducer of autophagy we genotyped the patients for these variants and correlated this to the phagocytic reaction.The genotyping was done with restriction fragment length polymorphisms analysis and the phagocytosis was determined with the pHrodo?Escherichia coli Bioparticles Phagocytosis kit for flowcytometry.RESULTS:In this study,we demonstrate that analysis of the monocyte and granulocyte populations of patients with CD and ulcerative colitis showed a comparable phagocytic activity(ratio of mean fluorescence intensity)between the patient groups and the healthy controls.CD patients show a significantly higher phagocytic capacity(ratio mean percentage of phagocytic cells)compared to healthy controls(51.91%±2.85%vs 37.67%±7.06%,P=0.05).The extend of disease was not of influence.However,variants of ATG16L1(WT:2.03±0.19 vs homozygoot variant:4.38±0.37,P<0.009)as well as NOD2(C-ins)(heterozygous variant:42.08±2.94 vs homozygous variant:75.58±4.34(P=0.05)are associated with the phagocytic activity in patients with CD.CONCLUSION:Monocytes of CD patients show enhanced phagocytosis associated with the presence of ATG16L1 and NOD2 variants.This could be part of the pathophysiological mechanism resulting in the disease.	Simone CS Wolfkamp Caroline Verseyden Esther WM Vogels Sander Meisner Kirsten Boonstra Charlotte P Peters Pieter CF Stokkers Anje A te Velde	2014	World Journal of Gastroenterology2014，20，10：	2
2	Postoperative plasma concentrations of procalcitonin after different types of surgery显示文摘	Meisner M Tschaikowsky K Hutzler A		0，，07：	1
3	Postoperative plasma concentration of procal-Citonin aften different types of surgery显示文摘	Meisner M Tschaikowsky K Hutzler A	1998	Intensive Care Med1998，24，11：	1
4	The relationship between large-scale convective rainfall and cold cloud over the western hemisphere during 1982- 1984显示文摘	ARKIN P A MEISNER B N	1987	Mon Wea Rev1987，115，1：	1
5	Adjustment of the GRACE score by growth differentiation factor 15 ena- bles a more accurate appreciation of risk in non-ST-eleva- tion acute coronary syndrome 显示文摘	Widera C Pencina MJ Meisner A	2011	Eur Heart J2011，33，：	1
6	Self-expanding metal stents for gastroduodenal malignancies:systematic review of their clinical effectiveness显示文摘	Dormann A Meisner S Verin N	2004	Endoscopy2004，36，：	1
7	Associations of carotid artery intima-media thickness (IMT) with risk factors and preva- lent cardiovascular disease: comparison of mean common carotid artery IMT with maximum internal carotid artery IMT显示文摘	Polak J F Pencina M J Meisner A	2010	Ultra- sound Med2010，29，：	1
8	Postoperative plasma concentrations of procalcitonin after different types of surgery显示文摘	Meisner M Tschaikowsky K Hutzler A	1998	Intensive Care Med1998，24，：	1
9	Effect of silicon, titanium, and zirconium ion implantation on NiTi biocompatibility 显示文摘	Meisner L L Lotkov A I Matveeva V A et aI	2012	Advances in Materials Science and Engineering2012，2012，：	1
10	Postoperative plasma concentrations of procalcitonin after different types of surgery 显示文摘	Meisner M Tschaikowsky K Hutzler A	1998	Intensive Caie Med1998，24，7：	1
11	Self-expanding metal stents for gstroduodenal malignancies systematic review of their clinical effectiveness显示文摘	Dormann A Meisner S Verin N	2004	Endoscopy2004，36，：	1
12	Postoperative plasma concentrations of procalcitonin after different types of surgery显示文摘	MEISNER M TSCHAIKOWSKY K HUTZLER A	1998	Intensive Care Med1998，24，7：	1
13	The inhaibitory effect of glucagon-like peptide-l(GLP-1)7-36 amide on gastric acid secretion in humans depends on an intact vagal innervations 显示文摘	Wettergren A Wojdemann M Meisner S	1997	Gut1997，40，：	1
14	Multi-criteria Decision Analysis as an Aid to the Strategic Planning of Energy R&D显示文摘	Lootsma F A J Meisner F Schellemans	1986	European Journal of Operations Research1986，，25：	1
15	Self-expanding metal stents for gastroduodenal malignancies: systematic review of their clinical effectiveness显示文摘	DORMANN A MEISNER S VERIN N	2004	Endoscopy2004，36，6：	1
16	Long-term cognitive and neurological outcome of preterm infants with postnatally acquired CMV infection through breast milk显示文摘	Goelz R Meisner C Bevot A	2013	Arch Dis Child Fetal Neonatal Ed2013，98，：	1
17	Postoperative plasmaconcentrations of procalcitonin after different types of surgery 显示文摘	Meisner M Tschaikowsky K Hutzler A	1998	Intensive Care Med1998，24，7：	1
18	Root hair occurrence and variation with environment显示文摘	MEISNER C A KARNOK K J	1991	Agronomy Journal1991，83，：	1
19	Peanut root response to drought stress显示文摘	Meisner C A Karnok K J	1992	Agronomy Journal1992，84，2：	1
20	Associations of carotid artery intima-media thickness (IMT) with risk factors and prevalent cardiovascular disease: Comparison of mean common carotid artery IMT with maximum internal carotid artery IMT显示文摘	Polak JF Pencina MJ Meisner A	2010	J Ultrasound Med2010，29，12：	1

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