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| 1 | VIPLFaceNet: an open source deep face recognition SDK显示文摘 | Xin LIU Meina KAN Wanglong WU Shiguang SHAN Xilin CHEN | 2017 | Frontiers of Computer Science2017，11，2： | 15 |
| 2 | Two RING-Finger Ubiquitin E3 Ligases Regulate the Degradation of SPX4, An Internal Phosphate Sensor, for Phosphate Homeostasis and Signaling in Rice显示文摘SPX-domain-containing proteins (SPXs) play an important role in inorganic phosphate (Pi) sensing,signaling,and transport in eukaryotes.In plants,SPXs are known to integrate cellular Pi status and negatively regulate the activity of Pi central regulators,the PHOSPATE STARVATION RESPONSE proteins (PHRs).The stability of SPXs,such as SPX4,is reduced under Pi-deficient conditions.However,the mechanisms by which SPXs are degraded remain unclear.In this study,using a yeast-twhybrid screen we iden.tified two RING-finger ubiquitin E3 ligases regulating SPX4 degradation,designated SDEL1 and SDEL2,which were post-transcriptionally induced by Pi starvation.We found that both SDELs were located in the nucleus and cytoplasm,had ubiquitin E3 ligase activity,and directly ubiquitinated the K^213 and K^299 lysine residues in SPX4 to regulate its stability.Furthermore,we found that PHR2,a Pi central regulator in rice,could compete with SDELs by interacting with SPX4 under Pi-sufficient conditions,which protected SPX4 from ubiquitination and degradation.Consistent with the biochemical function of SDEL1 and SDEL2,overexpression of SDEL1 or SDEL2 resulted in Pi overaccumulation and induced Pi-starvation signaling even under Pi-sufficient conditions.Conversely,their loss-of-function mutants displayed decreased Pi accumulation and reduced Pi-starvation signaling.Collectively,our study revealed that SDEL1 and SDEL2 facilitate the degradation of SPX4 to modulate PHR2 activity and regulate Pi homeostasis and Pi signaling in response to external Pi availability in rice. | Wenyuan Ruan Meina Guo Xueqing Wang Zhenhui Guo Zhuang Xu Lei Xu Hongyu Zhao Haiji Sun Chengqi Yan Keke Yi | 2019 | Molecular Plant2019，12，8： | 14 |
| 3 | Mechanisms involved in antineuralgic effects of Paeonia Lactiflora: prediction based on network pharmacology显示文摘目的:白芍的镇痛作用已被广泛应用于中医临床,但对其潜在机制知之甚少.本研究旨在从网络药理学的角度阐明其有效成分和镇痛机制.方法:通过中药系统药理学分析平台(TCMSP)筛选出其可能的活性成分及CAS.从Pubchem 中获得其SMILES,并通过在Swiss Target Prediction 数据库中反向对接获得潜在的靶点.从GeenCards 数据库中提取疼痛相关分子,采用韦恩图筛选出芍药治疗疼痛的预测靶点.机制分析采用String 构建蛋白-蛋白相互作用,运用DAVID 平台进行靶点GO 功能富集和KEGG 信号通路富集.结果:通过GO 和KEGG 分析我们发现疼痛相关的信号通路主要涉及血清素能突触、钙信号通路、调控TRP 通道的炎症介质.利用基于网络的系统生物学和分子对接分析,我们预测了白芍中的11 种活性成分和97 个潜在的治疗靶标.PRKCA、CASP3、ALOX15、SLC6A4、PRKCG、ALOX5、PRKCB、ALOX12、 EGFR、ADRB2、RYR3、RYR1、NOS2、PTAFR、PRKCQ、PRKCD 等基因参与了白芍的镇痛作用.结论:白芍可通过调节TRP 通道炎症介质、钙信号通路和5-羟色胺受体减轻疼痛.PRKCA、PRKCB、PRKCD、 PRKCQ 和PRKCG 可能是疼痛治疗的新靶标. | Di Zhang Shengsuo Ma Jianxin Sun Bing Yang Haoming Lin Meijing Xie Meina Huang Guoping Zhao | 2019 | TMR Clinical Research2019，2，2： | 8 |
| 4 | Traffic Prediction in 3G Mobile Networks Based on Multifractal Exploration显示文摘Traffic prediction plays an integral role in telecommunication network planning and network optimization. In this paper, we investigate the traffic forecasting for data services in 3G mobile networks. Although the Box-Jenkins model has been proven to be appropriate for voice traffic (since the arrival of calls follows a Poisson distribution), it has been demonstrated that the Internet traffic exhibits statistical self-similarity and has to be modeled using the Fractional AutoRegressive Integrated Moving Average (FARIMA) process. However, a few studies have concluded that the FARIMA process may fail in modeling the Internet traffic. To this end, we conducted experiments on the modeling of benchmark Internet traffic and found that the FARIMA process fails because of the significant multifractal characteristic inherent in the traffic series. Thereafter, we investigate the traffic series of data services in a 3G mobile network from a province in China. Rich multifractal spectra are found in this series. Based on this observation, an integrated method combining the AutoRegressive Moving Average (ARMA) and FARIMA processes is applied. The obtained experimental results verify the effectiveness of the integrated prediction method. | Yanhua Yu Meina Song Yu Fu Junde Song | 2013 | Tsinghua Science and Technology2013，18，4： | 6 |
| 5 | A reciprocal inhibitory module for Pi and iron signaling显示文摘Phosphorous(P)and iron(Fe),two essential nutrients for plant growth and development,are highly abundant elements in the earth's crust but often display low availability to plants.Due to the ability to form insoluble complexes,the antagonistic interaction between P and Fe nutrition in plants has been noticed for decades.However,the underlying molecular mechanism modulating the signaling and homeostasis between them re-mains obscure.Here,we show that the possible iron sensors HRZs,the iron deficiency-induced E3 ligases,could interact with the central regulator of phosphate(Pi)signaling,PHR2,and prompt its ubiquitination at lysine residues K319 and K328,leading to its degradation in rice.Consistent with this,the hrzs mutants dis-played a high Pi accumulation phenotype.Furthermore,we found that iron deficiency could attenuate Pi star-vation signaling by inducing the expression of HRZs,which in turn trigger PHR2 protein degradation.Inter-estingly,on the other hand,rice PHRs could negatively regulate the expression of HRZs to modulate iron deficiency responses.Therefore,PHR2 and HRZs form a reciprocal inhibitory module to coordinate Pi and iron signaling and homeostasis in rice.Taken together,our results uncover a molecular link between Pi and iron master regulators,which fine-tunes plant adaptation to Pi and iron availability in rice. | Meina Guo Wenyuan Ruan Yibo Zhang Yuxin Zhang Xueqing Wang Zhenhui Guo Long Wang Tian Zhou Javier Paz-Ares Keke Yi | 2022 | Molecular Plant2022，15，1： | 5 |
| 6 | 非小细胞肺癌的个体化治疗进展显示文摘肺癌是全球癌症相关死亡的最常见原因.在过去20年中,分子靶向治疗和免疫治疗显著改善了非小细胞肺癌(non-small-cell lung cancer,NSCLC)患者的预后.然而,绝大多数的晚期NSCLC会对目前治疗产生耐药,最终出现疾病进展.基于此,本综述就近年来出现的一些突破性NSCLC治疗方法,尤其是免疫治疗和靶向治疗展开讨论.同时强调了目前我们对耐药机制的理解以及将基因组分析纳入临床研究以进一步理解机制的重要性.我们认为新辅助和联合的维持治疗在未来有可能使早期阶段疾病得到治愈.合理的联合治疗未来发展所面临的主要挑战是如何通过可靠的预测性生物标志物将患者清晰分层.本文阐述了我们对未来十年可能影响NSCLC治疗策略的临床研究领域的观点. | Meina WANG Roy S HERBST Chris BOSHOFF 杨雪(译校) 赵军(译校) | 2022 | 中国肺癌杂志2022，25，3： | 5 |
| 7 | Aesthetic Evaluation and Application of Ornamental Plant Landscape显示文摘This paper employed the scenic beauty evaluation(SBE)method to study the relationship between the aesthetic preference of the public and the effect of ornamental plant groups.The results showed that color contrast,plant density,morphological diversity,and species diversity significantly affected the planting effect of ornamental plants.According to the aesthetic preference of the public reflected by scenic beauty model,strong contrasts in plant color,varied plant forms,suitable planting density,and appropriate arrangement of plants effectively improved the ornamental effect of plant groups. | ZHAO Qiangmin HU Chuanwei SUN Bing GAN Meina GAO Xue | 2017 | Journal of Landscape Research2017，9，5： | 4 |
| 8 | Survival difference between EGFR Del19 and L858R mutant advanced non-small cell lung cancer patients receiving gefitinib:a propensity score matching analysis显示文摘Objective: Although superior clinical benefits of epidermal growth factor receptor(EGFR) tyrosine kinase inhibitors(TKIs) in the treatment of advanced non-small-cell lung cancer(NSCLC) had been reported,the survival difference between exon 19 deletion(Del19) and exon 21 Leu858 Arg substitution(L858 R) remains controversial.The purpose of this study is to investigate the differences in progression-free survival(PFS) and overall survival(OS) between different EGFR mutant subtypes among advanced NSCLC patients receiving gefitinib.Methods: There were 204 advanced NSCLC patients with EGFR mutations treated with gefitinib were enrolled in this retrospective cohort study.Patients were divided into the EGFR Del19 group and the L858 R mutated group according to their mutant subtype.Propensity score matching(PSM) was conducted by using a nearest-neighbor algorithm(1:1) to adjust for demographical and clinical covariates.Survival curves were constructed with the Kaplan-Meier method and compared by using the log-rank test.Results: The PFS in Del19 group was similar to that in the L858 R group [before PSM 8.6 vs.7.2 months,P=0.072; after PSM 7.3 vs.7.2 months,P=0.155].No differences were detected in OS between the L858 R and the Del19 group(before PSM 17.8 vs.13.1 months,P=0.253; after PSM 16.9 vs.13.1 months,P=0.339).The Del19 group was significantly younger compared with the L858 R mutation group in age(P=0.015).Conclusions: No significant difference was found in the PFS or OS between the Del19 and L858 R mutant NSCLC patients receiving gefitinib.The age gap might contribute to the survival differences between Del19 and L858 R groups.PSM is of important value to the elimination of potential bias. | Minglei Zhuo Qiwen Zheng Jun Zhao Meina Wu Tongtong An Yuyan Wang Jianjie Li Shuhang Wang Jia Zhong Xue Yang Hanxiao Chen Bo Jia Zhi Dong Emei Gao JingjingWang Ziping Wang | 2017 | Chinese Journal of Cancer Research2017，29，6： | 4 |
| 9 | MS1 is essential for male fertility by regulating the microsporocyte cell plate expansion in soybean显示文摘Male sterility is an essential trait in hybrid seed production,especially for monoclinous and autogamous food crops.Soybean male-sterile ms1 mutant has been known for more than 50 years and could be instrumental in making hybrid seeds.However,the gene responsible for the male-sterile phenotype has remained unknown.Here,we report the map-based cloning and characterization of the MS1 gene in soybean.MS1 encodes a kinesin protein and localizes to the nucleus,where it is required for the male meiotic cytokinesis after telophase Ⅱ.We further substantiated that MS1 colocalizes with microtubules and is essential for cell plate formation in soybean male gametogenesis through immunostaining.Both ms1 and CRISPR/Cas9 knockout mutants show complete male sterility but are otherwise phenotypically normal,making them perfect tools for producing hybrid seeds.The identification of MS1 has the practical potential for assembling the sterility system and speeding up hybrid soybean breeding. | Xiaolong Fang Xiaoyuan Sun Xiangdong Yang Qing Li Chunjing Lin Jie Xu Wenjun Gong Yifan Wang Lu Liu Limei Zhao Baohui Liu Jun Qin Mengchen Zhang Chunbao Zhang Fanjiang Kong Meina Li | 2021 | Science China(Life Sciences)2021，64，9： | 4 |
| 10 | AVP(4-8) Improves Cognitive Behaviors and Hippocampal Synaptic Plasticity in the APP/PS1 Mouse Model of Alzheimer’s Disease显示文摘Memory deficits with aging are related to the neurodegeneration in the brain, including a reduction in arginine vasopressin(AVP) in the brain of patients with Alzheimer’s disease(AD). AVP(4-8), different from its precursor AVP, plays memory enhancement roles in the CNS without peripheral side-effects. However, it is not clear whether AVP(4-8) can improve cognitive behaviors and synaptic plasticity in the APP/PS1 mouse model of AD. Here, we investigated for the first time the neuroprotective effects of AVP(4-8) on memory behaviors and in vivo long-term potentiation(LTP) in APP/PS1-AD mice.The results showed that:(1) APP/PS1-AD mice had lower spontaneous alternation in the Y-maze than wild-type(WT) mice, and this was significantly reversed by AVP(4-8);(2) the prolonged escape latency of APP/PS1-AD mice in the Morris water maze was significantly decreased by AVP(4-8), and the decreased swimming time in target quadrant recovered significantly after AVP(4-8) treatment;(3) in vivo hippocampal LTP induced by high-frequency stimulation had a significant deficit in the AD mice, and this was partly rescued by AVP(4-8);(4) AVP(4-8)significantly up-regulated the expression levels of postsynaptic density 95(PSD95) and nerve growth factor(NGF)in the hippocampus of AD mice. These results reveal the beneficial effects of AVP(4-8) in APP/PS1-AD mice,showing that the intranasal administration of AVP(4-8)effectively improved the working memory and long-term spatial memory of APP/PS1-AD mice, which may be associated with the elevation of PSD95 and NGF levels in the brain and the maintenance of hippocampal synaptic plasticity. | Xiumin Zhang Fang Zhao Chenfang Wang Jun Zhang Yu Bai Fang Zhou Zhaojun Wang Meina Wu Wei Yang Junhong Guo Jinshun Qi | 2020 | Neuroscience Bulletin2020，36，3： | 3 |
| 11 | In vivo rapid fluorescence imaging of Alzheimer's disease through accurate target bio-marking of zinc gluconate显示文摘Alzheimer's disease(AD) is a progressive and age-related irreversible neurodegenerative disease. When AD occurs, the relevant amount of zinc ions in brain considerably changes. In this contribution, we have explored the possibility of in vivo rapid fluorescence imaging of AD through accurate targeting biomarker of zinc gluconate. By using the 3- and 6-month-old Alzheimer's model mice(AD-1) as the experimental models, our observations demonstrate that zinc gluconate molecules could pass through the blood–brain barrier and then produce hippocampus region-specific accumulation of fluorescent zinc nanoclusters in vivo, thus allowing kinetically controlled selective imaging of AD by fluorescence bioimaging. | Lanmei Lai Chunqiu Zhao Meina Su Jing Ye Hui Jiang Xuemei Wang | 2015 | Science Bulletin2015，60，16： | 3 |
| 12 | SP1 governs primordial folliculogenesis by regulating pregranulosa cell development in mice显示文摘Establishment of the primordial follicle(PF)pool is pivotal for the female reproductive lifespan;however,the mechanism of primordial folliculogenesis is poorly understood.Here,the transcription factor SP1 was shown to be essential for PF formation in mice.Our results showed that SP1 is present in both oocytes and somatic cells during PF formation in the ovary.Knockdown of Sp1 expression,especially in pregranulosa cells,significantly suppressed nest breakdown,oocyte apoptosis,and PF formation,suggesting that SP1 expressed by somatic cells functions in the process of primordial folliculogenesis.We further demonstrated that SP1 governs the recruitment and maintenance of Forkhead box L2-positive(FOXL2^+)pregranulosa cells using an Lgr5-EGFP-IRES-CreER^T2(Lgr5-KI)reporter mouse model and a FOXL2^+ cell-specific knockdown model.At the molecular level,SP1 functioned mainly through manipulation of NOTCH2 expression by binding directly to the promoter of the Notch2 gene.Finally,consistent with the critical role of granulosa cells in follicle survival in vitro,massive loss of oocytes in SP1 knockdown ovaries was evidenced before puberty after the ovaries were tranSP1anted under the renal capsules.Conclusively,our results reveal that SP1 controls the establishment of the ovarian reserve by regulating pregranulosa cell development in the mammalian ovary. | Han Cai Bingying Liu Huarong Wang Guanghong Sun Lizhao Feng Ziqi Chen Jiaqi Zhou Jiawei Zhang Tuo Zhang Meina He Tingting Yang Qirui Guo Zhen Teng Qiliang Xin Bo Zhou Hua Zhang Guoliang Xia Chao Wang | 2020 | Journal of Molecular Cell Biology2020，12，3： | 3 |
| 13 | A phase I study of nimotuzumab plus docetaxel in chemotherapy- refractory/resistant patients with advanced non-small-cell lung cancer显示文摘Background: To determine the safety and therapeutic efficacy of nimotuzumab(h-R3) combined with docetaxel in advanced non-small-cell lung cancer(NSCLC) patients who have failed to respond to prior first-line chemotherapy.Methods: In this single-center, open-label, dose-escalating phase I trial, patients with epidermal growth factor receptor(EGFR)-expressing stage IV NSCLC were treated with nimotuzumab plus docetaxel according to a dose escalation schedule. The safety and efficacy of the combination treatment were observed and analyzed.Results: There were 12 patients with EGFR-expressing stage IV NSCLC enrolled. The dose of nimotuzumab was escalated from 200 to 600 mg/week. The longest administration of study drug was 40 weeks at the 600 mg/week dose level. Grade III–IV toxicities included neutropenia and fatigue, and other toxicities included rash. Dose-limiting toxicity occurred with Grade 3 fatigue at the 200 mg dose level of nimotuzumab and Grade 4 neutropenia with pneumonia at the 600 mg dose level of nimotuzumab. No objective responses were observed, and stable disease was observed in eight patients(66.7%). The median progression-free survival(PFS) was 4.4 months in all patients, 1.3 months in patients with the EGFR mutation, and 4.4 months in those with wild type EGFR(EGFR WT). The median survival time(MST) was 21.1 months in all patients, 21.1 months in patients with EGFR mutation, and 26.4 months in patients with EGFR WT.Conclusions: Nimotuzumab and docetaxel combination therapy was found to be well tolerated and efficacious. Further study of nimotuzumab is warranted in advanced NSCLC patients. | Jun Zhao Minglei Zhuo Zhijie Wang Jianchun Duan Yuyan Wang Shuhang Wang Tongtong An Meina Wu Jie Wang | 2016 | Chinese Journal of Cancer Research2016，28，1： | 3 |
| 14 | New approach for the digital reconstruction of complex mine faults and its application in mining显示文摘Visualization of complex geological structures can technically support the accurate prediction and prevention of coal mine disasters.This study proposed a new digital reconstruction method to visualize geological structures based on establishing a virtual model in the digital twin system.This methodology for the digital reconstruction of complex fault structures comprises the following four aspects:(1)collection and fdelity of multi-physical feld data of the fault structures,(2)the transmission of multi-physical feld data,(3)the normalization of multi-physical feld data,and(4)digital model reconstruction of fault structures.The key scientifc issues of this methodology to be resolved include in situ fdelity of multi-feld data and normalized programming of multi-source data.In addition,according to the geological background and conditions in Da’anshan coal mine in western Beijing,China,a preliminary attempt is made to reconstruct a digital model of fault and fold structures using the methodology proposed in this study. | Hongwei Wang Zeliang Wang Yaodong Jiang Jiaqi Song Meina Jia | 2022 | International Journal of Coal Science & Technology2022，9，3： | 2 |
| 15 | Thermal Behavior Analysis of Stacked-type Supercapacitors with Different Cell Structures显示文摘As a new energy storage element,supercapacitors have characteristics such as high power density,fast charge and discharge rates,green environmental protection,and long cycle life.Temperature is an important parameter of supercapacitors which significantly influences the stability of the supercapacitors.In this study,the finite element method is used to realize a coupling between a one-dimensional electrochemical model and a three-dimensional thermal model.Then,based on this model,the concept of limited cycle numbers is defined,and different unit quantities,unit size,and the effect of temperature under different temperature environments such as low temperature,room temperature,and high temperature on stacked-type supercapacitors is studied.Finally,stacked-type supercapacitors are compared with rolled-type supercapacitors considering the same cell size,density,and volume approximations.The simulation results show that the higher the number of packaging units,the lower is the limit cycle number.This phenomenon is more pronounced under high current than under low current conditions.Increasing the package size of the porous electrode or separator decreases the limiting cycles.Under the same unit volume scenario,improving the separator size proportion can accurately control the temperature rise at small current values.Under the same material,volume,and density approximations,the temperature rises slowly for stacked-type supercapacitors as compared to rolled-type supercapacitors.This phenomenon is more pronounced with an increase in current. | Yansong Li Sihan Wang Meina Zheng Jun Liu | 2018 | CSEE Journal of Power and Energy Systems2018，4，1： | 2 |
| 16 | QoS prediction algorithm used in location-aware hybrid Web service显示文摘Quality-of-Service(QoS) describes the non-functional characteristics of Web services. As such, the QoS is a critical parameter in service selection, composition and fault tolerance, and must be accurately determined by some type of QoS prediction method. However, with the dramatic increase in the number of Web services, the prediction failure caused by data sparseness has become a critical challenge. A new ‘hybrid user-location-aware prediction based on weighted Adamic-Adar(WAA)'(HUWAA) was proposed. The implicit neighbor search was optimized by incorporating location factors. Meanwhile, the ability of the improved algorithms to solve the data sparsity problem was validated in experiments on public real world datasets. The new algorithm outperforms the existing of item-based pearson correlation coefficient(IPCC), user-based pearson correlation coefficient(UPCC) and Web service recommender system(WSRec) algorithms. | E Haihong Tong Junjie Song Meina Song Junde | 2015 | The Journal of China Universities of Posts and Telecommunications2015，22，1： | 2 |
| 17 | Abnormal event detection via the analysis of multi-frame optical flow information显示文摘Security surveillance of public scene is closely relevant to routine safety of individual.Under the stimulus of this concern,abnormal event detection is becoming one of the most important tasks in computer vision and video processing.In this paper,we propose a new algorithm to address the visual abnormal detection problem.Our algorithm decouples the problem into a feature descriptor extraction process,followed by an AutoEncoder based network called cascade deep AutoEncoder(CDA).The movement information is represented by a novel descriptor capturing the multi-frame optical flow information.And then,the feature descriptor of the normal samples is fed into the CDA network for training.Finally,the abnormal samples are distinguished by the reconstruction error of the CDA in the testing procedure.We validate the proposed method on several video surveillance datasets. | Tian WANG Meina QIAO Aichun ZHU Guangcun SHAN Hichem SNOUSSI | 2020 | Frontiers of Computer Science2020，14，2： | 2 |
| 18 | High Expression of ERCC1 Is a Poor Prognostic Factor in Chinese Patients with Non-small Cell Lung Cancer Receiving Cisplatin-based Therapy显示文摘Objective: to determine the role of excision repair cross-complementing group 1 gene (ERCC1) and ribonucleotide reductase subunit M1 (RRM1) expression in predicting response and survival in Chinese patients with advanced stage non-small cell lung cancer (NSCLC) treated with platinum-based chemotherapy. Methods: Formalin-fixed, paraffin-embedded biopsy tissues were retrospectively obtained from 160 advanced NSCLC patients. mRNA expression levels of ERCC1 and RRM1 were determined by real-time PCR. Results: Associations between mRNA expression level of ERCC1 and RRM1 and clinic-pathologic parameters were analyzed. One handred and forty two (88.75%) specimens were successfully amplified. mRNA expression level of ERCC1 and RRM1 was negatively associated with tumor response. ERCC1 expression levels ranged from 0.01 to 78.79 [median 0.63, mean 4.25 and standard deviation (SD) 9.23] and RRM1 from 0.00 to 30.91 (median 0.63, mean 0.87 and SD 3.36). By adopting cut-off values according to median expression levels, we found that MST in patients with low ERCC1 mRNA levels was significantly longer in overall population than in patients with higher levels (18.63 versus 13.69 months, log-rank 5.73, P=0.017), but we did not found the survival benefit of the patients with low expression level of RRM1. (19.07 versus 14.88, log-rank 1.66, P=0.197). Further, in the multivariable Cox regression model analysis we found that low level of ERCC1 expression, the presence of weight loss and target therapy, were significant prognostic factors for survival. Conclusion: ERCC1 expression is associated with patients’ survival in Chinese advanced NSCLC patients treated with platinum-based regimen and may serve as a biomarker in predicting tumor response and clinical outcome in the patient population. | Qing-zhi Guo Jie Wang Hua Bai Tong-tong An Meina Wu Jun Zhao Lu Yang Jian-chun Duan Yu-yan Wang Zhi-jie Wang | 2010 | Chinese Journal of Cancer Research2010，22，4： | 2 |
| 19 | Degradation of trace nitrobenzene in water by microwave-enhanced H2O2-based process显示文摘 | Honghu ZENG Lanjing LU Meina LIANG Jie LIU Yanghong LI | 2012 | Frontiers of Environmental Science & Engineering2012，6，4： | 1 |
| 20 | The development and characteristics of novel microneedle arrays fabricated from hyaluronic acid,and their application in the transdermal delivery of insulin显示文摘 | Liu Shu Jin MeiNa Quan YingShu | 2012 | J Control Release2012，161，93： | 1 |
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