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| 1 | Preassembly and ligand-induced restructuring of the chains of the IFN-γ receptor complex: the roles of Jak kinases, Statl and the receptor chains显示文摘 | Christopher D Krause Natasha Lavnikova Junxia Xie Erwen Mei Olga V Mirochnitchenko Yiwei Jia Robin M Hochstrasser Sidney Pestka | 2006 | Cell Research2006,16,1: | 7 |
| 2 | Glycogenic hepatopathy:A narrative review显示文摘Glycogenic hepatopathy(GH) is a rare complication of the poorly controlled diabetes mellitus characterized by the transient liver dysfunction with elevated liver enzymes and associated hepatomegaly caused by the reversible accumulation of excess glycogen in the hepatocytes. It is predominantly seen in patients with longstanding type 1 diabetes mellitus and rarely reported in association with type 2 diabetes mellitus. Although it was first observed in the pediatric population, since then, it has been reported in adolescents and adults with or without ketoacidosis. The association of GH with hyperglycemia in diabetes has not been well established. One of the essential elements in the pathophysiology of development of GH is the wide fluctuation in both glucose and insulin levels. GH and non-alcoholic fatty liver disease(NAFLD) are clinically indistinguishable, and latter is more prevalent in diabetic patients and can progress to advanced liver disease and cirrhosis. Gradient dual-echo MRI can distinguish GH from NAFLD; however, GH can reliably be diagnosed only by liver biopsy. Adequate glycemic control can result in complete remission of clinical, laboratory and histological abnormalities. There has been a recent report of varying degree of liver fibrosis identified in patients with GH. Future studies are required to understand the biochemical defects underlying GH, noninvasive, rapid diagnostic tests for GH, and to assess the consequence of the fibrosis identified as severe fibrosis may progress to cirrhosis. Awareness of this entity in the medical community including specialists is low. Here we briefly reviewed the English literature on pathogenesis involved, recent progress in the evaluation, differential diagnosis, and management. | Jagannath M Sherigar Joline De Castro Yong Mei Yin Debra Guss Smruti R Mohanty | 2018 | World Journal of Hepatology2018,10,2: | 7 |
| 3 | Involvement and therapeutic implications of airway epithelial barrier dysfunction in type 2 inflammation of asthma显示文摘Type 2 inflammation is a complex immune response and primary mechanism for several common allergic diseases including allergic rhinitis,allergic asthma,atopic dermatitis,and chronic rhinosinusitis with nasal polyps.It is the predominant type of immune response against helminths to prevent their tissue infiltration and induce their expulsion.Recent studies suggest that epithelial barrier dysfunction contributes to the development of type 2 inflammation in asthma,which may partly explain the increasing prevalence of asthma in China and around the globe.The epithelial barrier hypothesis has recently been proposed and has received great interest from the scientific community.The development of leaky epithelial barriers leads to microbial dysbiosis and the translocation of bacteria to inter-and sub-epithelial areas and the development of epithelial tissue inflammation.Accordingly,preventing the impairment and promoting the restoration of a deteriorated airway epithelial barrier represents a promising strategy for the treatment of asthma.This review introduces the interaction between type 2 inflammation and the airway epithelial barrier in asthma,the structure and molecular composition of the airway epithelial barrier,and the assessment of epithelial barrier integrity.The role of airway epithelial barrier disruption in the pathogenesis of asthma will be discussed.In addition,the possible mechanisms underlying the airway epithelial barrier dysfunction induced by allergens and environmental pollutants,and current treatments to restore the airway epithelial barrier are reviewed. | Xiang Dong Mei Ding Jinjin Zhang Ismail Ogülür Yagiz Pat Mübeccel Akdis Yadong Gao Cezmi A.Akdis | 2022 | Chinese Medical Journal2022,,5: | 4 |
| 4 | Use of multi-objective genetic algorithms to optimize inter-vehicle active suspension显示文摘 | Mei T X Goodall R M | 2002 | Journal of Rail and Rapid Transit2002,,: | 2 |
| 5 | Effect of dispersant concentration on slip casting of cordierite-based glass ceramics显示文摘 | MEI S YANG J FERREIRA M F | 2001 | J Colloid Inter Sci2001,241,: | 2 |
| 6 | Effect of dispersant concentration on slip casting of cordierite-based glass ceramics 显示文摘 | MEI Si YANG J FERREIRA M F | 2001 | J Colloid Interface Sci2001,241,: | 2 |
| 7 | Effect of MCI-154,a calcium sensitizer,on calcium sensitivity of myocardial contractile system in endotoxemic rats显示文摘 | Mei J M Hu D Y Chen H S | 2000 | Acta Pharmacol Sin2000,21,: | 2 |
| 8 | Experimental Investigation of the Creep Behavior of Garnet at High Temperatures and Pressures显示文摘To provide constraints on the rheological properties of garnet, we have experimentally investigated the creep behavior of garnet at high pressures and temperatures using a deformation-DIA. Samples were cold-pressed from a garnet powder and deformed at constant displacement rates ranging from 1.1×10-5 to 2.6×10-5 s-1 at high temperatures (1 273–1 473 K) and high pressures (2.4–4.1 GPa). Differential stress and pressure were measured using X-ray diffraction techniques based on the elastic strain of various lattice planes as a function of orientation with respect to the applied stress field. The plastic strain of a deforming sample was monitored in-situ through a series of radiographs. Our results provide a measure of the dependence of creep rate of garnet on the temperature with an activation en-ergy of ~280 kJ/mol and on pressure with an activation volume of ~10×10-6 m3/mol. The flow behavior of garnet quantified by this study provides the basis for modeling geodynamic processes occurring within subducted lithosphere. | Shenghua Mei Ayako M Suzuki David L Kohlstedt 许丽丽 | 2010 | Journal of Earth Science2010,21,5: | 2 |
| 9 | Morphological and molecular changes of maize plants after seeds beenflown on recoverable satellite显示文摘 | MEI M T QIU Y L HUANG Y Q | 1998 | Adv Space Res1998,22,12: | 2 |
| 10 | Immunomodulatory activity of polysaccharide isolated from Angelica sinensis 显示文摘 | Tiehong Y Mei J Qibing M | 2006 | International Journal of Biological Macromolecules2006,39,45: | 1 |
| 11 | Study of the friction error for a high-speed high precision table显示文摘 | Mei X S Tsutsumi M S Yamazaki T | 2001 | Machine Tool & Manufacturing2001,41,: | 1 |
| 12 | Comparison of fractional Inhibitory concentration index with response surface modeling for characterization of in vitro interaction of antifungals against itraconazole-susceptible and -resistant asporgillus fumigatus isolates 显示文摘 | TE DORSTHORST D T A VERWEIJ P E MEIS J F G M | 2002 | Antimicrob Agents Chemother2002,46,3: | 1 |
| 13 | 显示文摘 | Yang Juan Mei Sen Ferreira J M F | 2001 | J Am Ceram Soc2001,84,8: | 1 |
| 14 | Identification of a Spindlin homolog in gibel carp(Carassius auratus gibelio)显示文摘 | Wang X L Sun M Mei J | 2005 | Comp Biochem Physiol2005,141,: | 1 |
| 15 | Purification of recombinant hep-atitis B virus surface antigen produced by transformed ChineseHamster Ovary(CHO)cell line grown in culture显示文摘 | Belew M Mei Y Li B | 1991 | Biosepa-ration1991,1,: | 1 |
| 16 | Effect of Fatty Acid Addition on the Properties of Biopolymer Films Based on Lipophilic Maize Starch and Gelatin 显示文摘 | F M FAKHOURI L C B FONTES L H INNOCENTINI- MEI | 2009 | Starch-Starke2009,,61: | 1 |
| 17 | Assessment of iron status in US pregnant women from the National Health and Nutrition Examination Survey (NHANES), 1999 - 2006显示文摘 | MEI Z G COGSWELL M E LOOKER A C | 2011 | Am J Clin Nutr2011,93,: | 1 |
| 18 | A novel improved variable step-size incremental-resistance MPPT method for PV systems 显示文摘 | MEI Q SHAN M W LIU L Y | 2011 | IEEE Transactions on Industrial Electronics2011,58,6: | 1 |
| 19 | Study on the load distribution of ball screws with errors 显示文摘 | Mei X S Tsutsumi M Tao T | 2003 | Mechanism and Machine Theory2003,38,11: | 1 |
| 20 | Interface properties and thermodynamic analysis of laser-arc hybrid welded Al/steel joint显示文摘 | Mei S W Gao M Yan J | 2013 | Science and Technology of Welding and Joining2013,18,4: | 1 |