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| 1 | Abdominal pain related to adulterated opium:An emerging issue in drug addicts显示文摘Lead may contaminate opium,heroin and illicit opiates and is particularly observed in Iran.Lead,a natural heavy metal is able to interfere with several organ functions after ingestion or inhalation.Lead poisoning manifestations are non-specific and thus lead poisoning remains difficult to diagnose.Among the manifestations,abdominal pain is almost the most frequent symptom causing patients to seek medical care.In patients with a history of opium addiction presenting with moderate-to-severe abdominal pain,lack of diagnosis of lead toxicity may thus result in time-consuming and unnecessary medical work-ups that can end up in invasive surgery.This paper aims to briefly review abdominal pain as an emergency issue and the leading symptom of lead poisoning that brings most of the patients to healthcare facilities.All published adult cases and case series of opium addicts admitted with abdominal pain due to leadadulterated opium consumption have been reviewed.A trend of increasing numbers of lead poisoning cases has recently emerged among opium addicts in Iran.Due to the non-specific manifestations and hazardous effects,psychiatrists and emergency physicians should consider lead poisoning in patients with a past or present history of opium addiction referred for acute abdominal pain,particularly in case of colicky abdominal pain. | Maryam Vahabzadeh Bruno Megarbane | 2020 | World Journal of Psychiatry2020，10，5： | 3 |
| 2 | Current recommendations for treatment toxic alcohol poisonings显示文摘 | Borron SW Baud FJ | 2005 | Intensiv Care Med2005，31，2： | 1 |
| 3 | Drug Fever: a descriptive cohort study from the French national pharmacovigilance database显示文摘 | Vodovar D Lebeker C Megarbane B | 2012 | Drug Saf2012，35，9： | 1 |
| 4 | Antidotnal treatment of cyanide poisoning显示文摘 | Megarbane B Delahaye A Goldgran-Toledano D | 2003 | J Chin Med Assoc2003，66，4： | 1 |
| 5 | Does high-dose buprenorphine cause respiratory depression:possible mechanisms and therapeutic consequences显示文摘 | Megarbane B Hreiche R Pirnay S | 2006 | Toxicol Rev2006，25，2： | 1 |
| 6 | Emergency feasibility in medical intensive care unit of extracorporeal life support for refractory cardiac arrest显示文摘 | Megarbane B Leprlnce P Deye N | 2007 | Intensive Care Med2007，33，5： | 1 |
| 7 | Antidotal treatment of cyanide poisoning 显示文摘 | Megarbane B Delahaye A Goldgran-Toledano D | 2003 | J Chin Med Assoc2003，66，4： | 1 |
| 8 | Unknown diagnosis in two male cousins with facial abnormalities,optic atrophy,abnormal EEG,and severe psychomotor retardation显示文摘 | Megarbane A | 2003 | Am J Med Genet2003，116，4： | 1 |
| 9 | Recombinant human activated protein C for adults with septic shock: a randomized controlled trial 显示文摘 | Annane D Timsit J F Megarbane B | 2013 | Am J Respir Crit Care Med2013，187，10： | 1 |
| 10 | Antidotal treatment of cyanide poisoning 显示文摘 | Megarbane B Delahaye A Goldgran Toledano D | 2003 | Chin Med Assoc2003，66，4： | 1 |
| 11 | Femoral vs jugular venous catheterization and risk of nosocomial events in adults requiring acute renal replacement therapy:A randomized con trolled trial显示文摘 | Parienti JJ Thirion M Megarbane B el al | 2008 | Jama May2008，299，20： | 1 |
| 12 | Emergency feasibility in medical intensive care unit of extracorporeal life support for refractory cardiac arrest显示文摘 | Megarbane B Leprince P Deye N | 2007 | Intensive Care Med2007，33，5： | 1 |
| 13 | X-linked transposition of the great arteries and incomplete penetrance among males with a nonsence mutation in ZIC3显示文摘 | Megarbane A Salem N Stephan E | 2000 | Eur J Hum Genet2000，8，9： | 1 |
| 14 | Hydroxocobalamin for severe acute cyanide poisoning by ingestion or inhalation显示文摘 | Borron SW Baud FJ Megarbane B | 2007 | Am J Emerg Med2007，25，5： | 1 |
| 15 | Increased diffusion of soluble adhesion molecules in meningitis,severe sepsis and systemic inflammatory response without neurological infection is associated with intrathecal shedding in cases in meningitis显示文摘 | Megarbane B Marchal P Marfaing-Koka A | 2004 | Intensive Care Med2004，30，5： | 1 |
| 16 | Femoral vs jugular venous catheterization and risk of nosocomial events in adults requiring acute renal replacement therapy:a randomized controlled trial显示文摘 | Parienti JJ Thirion M Megarbane B | | 0，，20： | 1 |
| 17 | Extracorporeal life support in a case of acute carbamazepine poisoning with life-threatening refractory myocardial failure 显示文摘 | Megarbane B Leprince P Deye N | 2006 | Intensive Care Med2006，32，9： | 1 |
| 18 | Emergency feasibility in medical intensive care unit of extracorporeal life support for refractory cardiac arrest 显示文摘 | MEGARBANE B LEPRINCE P DEYE N | 2007 | Int Care Med2007，33，5： | 1 |
| 19 | New colistin population pharmacokinetic data in critically ill patients suggesting an alternative loading dose rationale显示文摘 | Gregoire N Mimoz O Megarbane B | 2014 | Antimicrob Agents Chemother2014，58，12： | 1 |
| 20 | Interaction of drugs of abuse and maintenance treatments with human P-glycoprotein(ABCB1)and breast cancer resistance protein(ABCG2)显示文摘 | Tournier N Chevillard L Megarbane B | 2010 | Int J Neuropsychopharmacol2010，13，7： | 1 |
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