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| 1 | Endoscopic retrograde cholangiography for pediatric choledocholithiasis: Assessing the need for endoscopic intervention显示文摘AIM:To assess pediatric patients for choledocholithiasis.We applied current adult guidelines to identify predictivefactors in children.METHODS:A single-center retrospective analysis was performed at a tertiary children's hospital.We evaluated 44 consecutive pediatric patients who underwent endoscopic retrograde cholangiography(ERCP) for suspected choledocholithiasis.Patients were stratified into those with common bile duct stones(CBDS) at ERCP vs those that did not using the American Society of Gastrointestinal Endoscopy(ASGE) guidelines(Very Strong and Strong criteria) for suspected CBDS.RESULTS:CBDS were identified in 84% at the time of ERCP.Abdominal ultrasound identified CBDS in 36% of patients.Conjugated bilirubin ≥ 0.5 mg/d L was an independent risk factor for CBDS(P = 0.003).The Very Strong(59.5%) and Strong(48.6%) ASGE criteria identified the majority of patients(P = 0.0001).A modified score using conjugated bilirubin had a higher sensitivity(81.2% vs 59.5%) and more likely to identify a stone than the standard criteria,odds ratio of 25.7 compared to 8.8.Alanine aminotransferase and gamma-glutamyl transferase values identified significant differences in a subset of patients with odds ratio of 4.1 and 3.25,respectively.CONCLUSION:Current adult guidelines identified the majority of pediatric patients with CBDS,but specific pediatric guidelines may improve detection,thus decreasing risks and unnecessary procedures. | Douglas S Fishman Bruno P Chumpitazi Isaac Raijman Cynthia Man-Wai Tsai E O’Brian Smith Mark V Mazziotti Mark A Gilger | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，11： | 6 |
| 2 | Osteosarcopenia in autoimmune cholestatic liver diseases:Causes,management,and challenges显示文摘Primary biliary cholangitis and primary sclerosing cholangitis(PSC)are the most common cholestatic liver diseases(CLD)in adults and are both characterized by an immune pathogenesis.While primary biliary cholangitis is a model autoimmune disease,with over 90%of patients presenting very specific autoantibodies against mitochondrial antigens,PSC is considered an immune mediated disease.Osteoporosis is the most common bone disease in CLD,resulting in frequent fractures and leading to significant morbidity.Further,sarcopenia is emerging as a frequent complication of chronic liver diseases with a significant prognostic impact and severe implications on the quality of life of patients.The mechanisms underlying osteoporosis and sarcopenia in CLD are still largely unknown and the association between these clinical conditions remains to be dissected.Although timely diagnosis,prevention,and management of osteosarcopenia are crucial to limit the consequences,there are no specific guidelines for management of osteoporosis and sarcopenia in patients with CLD.International guidelines recommend screening for bone disease at the time of diagnosis of CLD.However,the optimal monitoring strategies and treatments have not been defined yet and vary among centers.We herein aim to comprehensively outline the pathogenic mechanisms and clinical implications of osteosarcopenia in CLD,and to summarize expert recommendations for appropriate diagnostic and therapeutic approaches. | Nicola Pugliese Ivan Arcari Alessio Aghemo Andrea G Lania Ana Lleo Gherardo Mazziotti | 2022 | World Journal of Gastroenterology2022，28，14： | 2 |
| 3 | High serum osteoprotegerin levels in patients with hyperthyroidism: effect of medical treatment 显示文摘 | Amato G Mazziotti G Sorvillo F | 2004 | Italy Bone2004，35，3： | 1 |
| 4 | Growth hormone,insulin like growth factors,and the skeleton显示文摘 | Giustina A Mazziotti G Canalis E | | 0，，： | 1 |
| 5 | Glucocorticoid-in- duced osteoporosis: pathophysiology and therapy 显示文摘 | Canalis E Mazziotti G Giustina A | 2007 | Osteoporos Int2007，18，10： | 1 |
| 6 | Serum TSH values and risk of vertebral fractures in euthyrnid post-menopausal women with low bone mineral density显示文摘 | Mazziotti G Porcelli T Patelli I ct al | 2010 | Bone2010，46，3： | 1 |
| 7 | Reevaluating thyrotro- pin receptor-induced mouse models of Graves' disease and ophthalmopathy 显示文摘 | Baker G Mazziotti G von Ruhland C | 2005 | Endocrinology2005，146，2： | 1 |
| 8 | Successful liver transplantation using an 87 year-old donor显示文摘 | Mazziotti A Cescon M Graxi GL | 1999 | Hepatogastroenterology1999，46，27： | 1 |
| 9 | High prevalence of radiological vertebral fractures in HIV-infected males 显示文摘 | Torti C Mazziotti G Soldini PA | 2012 | Endocrinology2012，41，3： | 1 |
| 10 | Successful liver transplantation using an 87 year-old donor显示文摘 | Mazziotti A Cescon M Grazi GL | 1999 | Hepato- gastroenterology1999，46，27： | 1 |
| 11 | Drug-induced osteoporosis: mechanisms and clinical implications显示文摘 | Mazziotti G Canalis E Giustina A | 2010 | Am J Med2010，123，10： | 1 |
| 12 | Growth hormone, insulinlike growth factors, and the skeleton显示文摘 | Giustina A Mazziotti G Canalis E | 2008 | Endocrine Rev2008，29，5： | 1 |
| 13 | Harmonic US imaging of vesicoureteric reflux in children: usefulness of a second generation US contrast agent显示文摘 | Ascenti G Zimbaro G Mazziotti S | 2004 | Pediatr Radiol2004，34，6： | 1 |
| 14 | Recombinant human TSH modulates in vivo C-telopeptides of type-1 collagen and bone alkaline phosphatase, but not osteoprotegerin production in postmenopausal women monitored for differentiated thyroid carcinoma显示文摘 | Mazziotti G Sorvillo F Piscopo M | 2005 | J Bone Miner Res2005，20，3： | 1 |
| 15 | Serum thyrotropin receptor antibodies concentrations in patients with Graves' disease before, at the end of methimazole treatment, and after drug withdrawal: evidence that the activity of thyrotropin receptor antibody and/or thyroid response modify during the observation period显示文摘 | Carella C Mazziotti G Sorvillo F | 2006 | Thyroid2006，16，3： | 1 |
| 16 | transanal onestage pull-through for Hirchsprung,s disease显示文摘 | Minkes PK Mazziotti MV | 1999 | J Pediatr Surg1999，34，： | 1 |
| 17 | Transanal one-stagesoave procedure for infants with Hirschsprung' s disease显示文摘 | langer JC Minkes PK Mazziotti MV | 1999 | J Pediart Surg1999，34，： | 1 |
| 18 | Growth hormone, insulin-like growth factors, and the skeleton 显示文摘 | Giustina A Mazziotti G Canalis E | 2008 | Endoer Rev2008，29，5： | 1 |
| 19 | Glucocorti- coid-indueed osleoporosis: an update 显示文摘 | MAZZIOTTI G AN(JELl A BILEZIKIAN JP | 2006 | Trends Endoerinol Metab2006，7，4： | 1 |
| 20 | Intestinal rotation abnormalities without volvulus: the role of laparoscopy显示文摘 | Mazziotti MV Strasberg SM LangerJC | 1997 | J Am Coli Surg1997，185，2： | 1 |
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