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1057篇 您的检索式:作者名="Mayer P"
    题名 作者 年代 出处 被引量
1CDX2 protein expression compared to alcian blue staining in the evaluation of esophageal intestinal metaplasia显示文摘AIM:To compare the sensitivity and specificity of CDX2 and alcian blue(AB) p H 2.5 staining in identifying esophageal intestinal metaplasia.METHODS:One hundred and ninty-nine biopsies from 186 patients were retrospectively reviewed and categorized as Barrett's esophagus(BE)(n =108); non-Barrett's esophagus(NBE)(n =48); columnar blue cells(CB) and esophageal glands(EG)(n =43).The biopsies were stained with AB and immunostained for CDX2 using a mouse monoclonal antibody from Biogenex(clone CDX2-88) and the Ventana Discovery X automated immunostainer.The positive and negative predictive value of each group was used to determine the predictive power of CDX2 and AB in diagnosing intestinal metaplasia.RESULTS:All of the 108 BE biopsies(100%) were positive for AB and 102 of them(94.4%) were positive for CDX2.The six BE patients(5.6%) who failed to stain with CDX2 were found to have lost the focus of intestinal metaplasia upon deeper sectioning for immunostaining.Both AB and CDX2 were negative in 43 out of 48(89.6%) NBE cases.Five NBE patients(10.4%) were falsely positive for AB due to the presence of EG and CB in these biopsies.These cases were all CDX2 negative.In addition,5 AB negative NBE were found to be CDX2 positive.Based on these results the CDX2 immunostain had similar sensitivity but higher specificity(100% vs about 91%) than AB in detecting intestinal type metaplasia in these samples.Our data shows that CDX2 has a better PPV in detecting intestinal metaplasia as compared to AB(95.6% vs 71.5%,respectively).CONCLUSION:CDX2 has a better positive predictive value than AB in detecting intestinal metaplasia.CDX2may be useful when challenged by gastro-esophageal biopsies containing mimikers of BE.Dennis R Johnson Maisoun Abdelbaqui Maryam Tahmasbi Zoltan Mayer Hung-Wei Lee Mokenge P Malafa Domenico Coppola 2015World Journal of Gastroenterology2015,21,9:2
2以欧3柴油机为基础开发达到欧4标准的发动机显示文摘为了说明未来排放研究的重点,论述了排放法规和瞬态试验循环问题。给出了满足欧4排放标准的可供选择的对策,并讨论了达到排放标准所需的最重要的基本发动机技术和排气后处理技术。AVL研发工作的结果指出了进一步降低排放以达到欧4及以后排放标准要求的潜力。Mayer K P 2007国外内燃机2007,39,6:2
3The Effect of Financial Development on Convergence:Theory and Evidence显示文摘Aghion P Howitt P Mayer - Foulkes 2005The Quarterly Journal of Economics2005,,:1
4Topical use of chitosan in ophthalmology:tolerance assessment and evaluation of precorneal retention显示文摘Felt O Furrer P Mayer JM 1999Int J Pharm1999,180,:1
5HSPT0 chaperones: cellular functions and molecular mechanism 显示文摘MAYER M P BUKAU B 2005Cell Mol Life Sci2005,62,6:1
6A Simplified Method for the Preparation of Fungal genomic DNA for PCR and RAPD analysis显示文摘Graham GC Mayers P Henry RT 1994Biotechniques1994,16,1:1
7Efficient screening of process variables 显示文摘STOWE R A MAYER R P 1966Industrial and Engineering Chemistry1966,58,2:1
8Differences in the rapeutic indexes of combination entronomic chemotherapy and an axeno graftsb 显示文摘Klement G Huang P Mayer B 2002Clin Cancer Res2002,8,1:1
9Emotional intelligence as a standard intelligence显示文摘MAYER J D SALOVEY P CARUSO D R SITARENIOS G 2001Emotion2001,,3:1
10beta-Adrenergic stimulation of rat cardiac fibroblasts promotes protein synthesis via the activation af phosphatidylinositol 3-kinase 显示文摘Colombo F Noal J Mayers P 2001J Mol Cell Cardiol2001,33,3:1
11Emotional intelligence 显示文摘Salovey P Mayer J D 1989Imagination cognition and personality1989,9,3:1
12Emotional Intelligence Imagination 显示文摘Salovey P Mayer J D 1990Cognition-and-Personality1990,9,:1
13Chemical changes due to acid precipitation in a loess-derived soil in central Europe显示文摘Ulrich B Mayer R R Khanna P K 1980Soil Science1980,130,4:1
14Assessment of intake from the diet显示文摘R Kroes D Müller J Lambe M.R.H L?wik J van Klaveren J Kleiner R Massey S Mayer I Urieta P Verger A Visconti 2002Food and Chemical Toxicology2002,,2:1
15Cellulose biosynthesis and function in bacteria显示文摘Ross P Mayer R Benziman M 1991Microbiological Reviews1991,55,1:1
16Enhanced diffusion of polycyelic aromatic hydrocarbons in artificial and natural aqueous solutions 显示文摘Mayer P Fernqvist M M Christensen P 2007Environmental Science and Technology2007,41,17:1
17Emotional intelli- gence meets traditional standards for an intelligence显示文摘Mayer J D Caruso D R Salovey P 1999Intelligence1999,27,4:1
18Oxygenation status of gynecologic tumors:What is the optimal hemoglobin level? 显示文摘Vaupel P Thews O Mayer A 2002Strahlenther Oncol2002,178,:1
19A simplified method for the preparation of fungal genomic DNA for PCR and RAPD analysis显示文摘 Mayers P Henry R J 1994Biotechniques1994,16,1:1
20Factors predicting perioperatire cytokine response in patients undergoing liver transplantation 显示文摘Miki C McMaster P Mayer AD 2000Crit Care Med2000,28,2:1
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