|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Recent advances and remaining gaps in our knowledge of associations between gut microbiota and human health显示文摘The complex gut microbial flora harbored by individuals(microbiota) has long been proposed to contribute tointestinal health as well as disease. Pre-and probioticproducts aimed at improving health by modifyingmicrobiota composition have already become widelyavailable and acceptance of these products appearsto be on the rise. However, although required forthe development of effective microbiota basedinterventions, our basic understanding of microbiotavariation on a population level and its dynamics withinindividuals is still rudimentary. Powerful new parallelsequence technologies combined with other efficientmolecular microbiota analysis methods now allow forcomprehensive analysis of microbiota composition inlarge human populations. Recent fi ndings in the fi eldstrongly suggest that microbiota contributes to thedevelopment of obesity, atopic diseases, inflammatorybowel diseases and intestinal cancers. Through theongoing National Institutes of Health Roadmap 'HumanMicrobiome Project' and similar projects in other partsof the world, a large coordinated effort is currentlyunderway to study how microbiota can impact humanhealth. Translating findings from these studies intoeffective interventions that can improve health,possibly personalized based on an individuals existingmicrobiota, will be the task for the next decade(s). | Volker Mai Peter V Draganov | 2009 | World Journal of Gastroenterology2009，15，1： | 21 |
| 2 | Diarrheagenic Escherichia coli infection in Baltimore, Maryland, and New Haven, Connecticut 显示文摘 | Nataro JP Mai V Johnson J | 2006 | Clin Infect Dis2006，43，4： | 1 |
| 3 | Efficacy ofauto -crosslinked hyaluronan gel for adhesion prevention in lapa- roscopy and hysteroscopy : a systematic review and meta - analysis of randomized controlled trials 显示文摘 | MAIS V CIRRONIS M G PEIRETTI M | 2012 | Eur J Obstet Gynecol Reprod Biol2012，160，1： | 1 |
| 4 | Efficacy of auto-crosslinked hyaluronan gel for adhesion prevention in laparoscopy and hysteroscopy: A systematic review and meta-analysis of randomized controlled trials显示文摘 | MAIS V CIRRONIS M G PEIRETTI M | 2012 | Eur J Obstet Gynecol Reprod Biol2012，160，1： | 1 |
| 5 | Cytotoxicity of rhamnosylanthraquinones and rhamnosylanthrones from Rhamnus nepalensis 显示文摘 | Mai L P Gueritte F Dumontet V | 2001 | J Nat Prod2001，64，9： | 1 |
| 6 | Sens Actuators A显示文摘 | Cheng Z Y Bharti V Xu T B Xu Haisheng Mai T and Zhang Q M | 2001 | 90:1382001，90，： | 1 |
| 7 | Dietary fiber and risk of colorectal cancer in the Breast Cancer Detection Demonstration Project (BCDDP) follow-up cohort显示文摘 | MAI V FLOOD A PETER U | 2003 | Int J Epidemiol2003，32，： | 1 |
| 8 | Development and evaluation of a novel loop mediated isothermal amplification method for rapid detection of sever acute respiratory syndrome coronavirus显示文摘 | Hong T C Mai Q L Cuong D V | 2004 | Journal of Clinic Microbiology2004，4，： | 1 |
| 9 | Associations between dietary habits and body mass index with gut microbiota composition and fecal water genotoxicity: an observational study in African American and Caucasian American volunteers 显示文摘 | Mai V McCrary QM Sinha R | 2009 | Nutr J2009，8，： | 1 |
| 10 | B7S1,a novel B7 family member that negatively regulates T cell activation显示文摘 | PRASAD D V RICHARDS S MAI X M | 2003 | Immunity2003，18，： | 1 |
| 11 | Development and evaluation of a novel loopmediated isothermal amplification method for rapid detection of severe acute respiratory syndrome coronavirus显示文摘 | Hong T C Mai Q L Cuong D V | 2004 | J Clin Microbiol2004，42，： | 1 |
| 12 | Development and evaluation of a novel loop-mediated isothermal amplification method for rapid de- tection of severe acute respiratory syndrome coronavirus 显示文摘 | Hong T C Mai Q L Cuong D V | 2004 | J Clin Microbiol2004，42，5： | 1 |
| 13 | B7S1,a novel B7 family member that negatively regulates T cell activation显示文摘 | PRASAD D V RICHARDS S MAI X M | 2003 | Immunity2003，18，6： | 1 |
| 14 | Perfusion imaging of the human lung using flow sensitive alternating inversion recovery with an extra radiofrequency pulse显示文摘 | Mai V Klaus D John M | 1999 | Magn Reson Imaging1999，17，3： | 1 |
| 15 | Developmentand evaluation of a novel loop-mediated isothermal am-plification method for rapid detection of severe acute re-spiratory syndrome coronavirus显示文摘 | Hong T C Mai Q L Cuong D V | 2004 | J Clin Microbiol2004，42，5： | 1 |
| 16 | Development and evaluation of a novel loop-mediated isothermal amplification method for rapid detection of severe acute respiratory syndrome coronavirus显示文摘 | Hong T C Mai Q L Cuong D V | 2004 | J Clin Microbiol2004，42，5： | 1 |
| 17 | Understanding the extent and sources of variation in gut microbiota studies; a prerequisite for establishing associations with disease显示文摘 | Mai V Ukhanova M Baer D J | 2010 | Diversity2010，2，9： | 1 |
| 18 | Determinants of adenomyosis in women who underwent hysterectomy for benign gynecological conditions:results form a prospective multicentric study in Italy显示文摘 | PARAZZINIF MAIS V CIPPRIANI S ct al | 2013 | European luomsl of Obstetrics &Gynecology and Reproductive Biology2013，143，： | 1 |
| 19 | Risk of psychiatric disorders among individuals reporting same-sex sexual partners in the national comorbidity survey显示文摘 | GILMAN S E COCHRAN S D MAYS V M | 2001 | Am J Public Health2001，91，6： | 1 |
| 20 | Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase Ⅱ randomised placebo-controlled double-blind multicentre trial显示文摘Rationale Haematoma growth is common early after intracerebral haemorrhage(ICH),and is a key determinant of outcome.Tranexamic acid,a widely available antifibrinolytic agent with an excellent safety profile,may reduce haematoma growth.Methods and design Stopping intracerebral haemorrhage with tranexamic acid for hyperacute onset presentation including mobile stroke units(STOP-MSU)is a phase Ⅱ double-blind,randomised,placebo-controlled,multicentre,international investigator-led clinical trial,conducted within the estimand statistical framework.Hypothesis In patients with spontaneous ICH,treatment with tranexamic acid within 2 hours of onset will reduce haematoma expansion compared with placebo.Sample size estimates A sample size of 180 patients(90 in each arm)would be required to detect an absolute difference in the primary outcome of 20%(placebo 39%vs treatment 19%)under a two-tailed significance level of 0.05.An adaptive sample size re-estimation based on the outcomes of 144 patients will allow a possible increase to a prespecified maximum of 326 patients.Intervention Participants will receive 1 g intravenous tranexamic acid over 10 min,followed by 1 g intravenous tranexamic acid over 8 hours;or matching placebo.Primary efficacy measure The primary efficacy measure is the proportion of patients with haematoma growth by 24±6 hours,defined as either≥33%relative increase or≥6 mL absolute increase in haematoma volume between baseline and follow-up CT scan.Discussion We describe the rationale and protocol of STOP-MSU,a phase Ⅱ trial of tranexamic acid in patients with ICH within 2 hours from onset,based in participating mobile stroke units and emergency departments. | Nawaf Yassi Henry Zhao Leonid Churilov Bruce C V Campbell Teddy Wu Henry Ma Andrew Cheung Timothy Kleinig Helen Brown Philip Choi Jiann-Shing Jeng Annemarei Ranta Hao-Kuang Wang Geoffrey C Cloud Rohan Grimley Darshan Shah Neil Spratt Der-Yang Cho Karim Mahawish Lauren Sanders John Worthington Ben Clissold Atte Meretoja Vignan Yogendrakumar Mai Duy Ton Duc Phuc Dang Nguyen Thai My Phuong Huy-Thang Nguyen Chung Y Hsu Gagan Sharma Peter J Mitchell Bernard Yan Mark W Parsons Christopher Levi Geoffrey A Donnan Stephen M Davis | 2022 | Stroke & Vascular Neurology2022，7，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员