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1Relationship between the exocrine and endocrine pancreas after acute pancreatitis显示文摘AIM:To determine the prevalence and time course of pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.METHODS:Relevant literature cited in three major biomedical journal databases(EMBASE,MEDLINE,and Scopus)was reviewed independently by two authors.There were no language constraints but the search was limited to human studies.Studies included were cohort studies of adult patients who were discharged after an attack of acute pancreatitis.Patients were excluded if they were under 18 years of age or had a previous diagnosis of prediabetes or diabetes mellitus,pancreatic exocrine insufficiency,or chronic pancreatitis.The main outcome measure was the prevalence of concomitant pancreatic exocrine insufficiency in patients who were diagnosed with prediabetes and diabetes mellitus after an attack of acute pancreatitis.Subgroup analysis was conducted for patients who were diagnosed with prediabetes only and those who were diagnosed withdiabetes mellitus only.Subgroup analysis looking at the time course of concomitant pancreatic exocrine and endocrine insufficiency was also conducted.Pooled prevalence and corresponding 95%confidence intervals were calculated for all outcome measures and P-values<0.05 were deemed statistically significant.RESULTS:Eight clinical studies comprising of 234patients met all eligibility criteria.The pooled prevalence of newly diagnosed prediabetes or diabetes in individuals after acute pancreatitis was 43%(95%CI:30%-56%).The pooled prevalence of pancreatic exocrine insufficiency in individuals after acute pancreatitis was 29%(95%CI:19%-39%).The prevalence of concomitant pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes was 40%(95%CI:25%-55%).The prevalence of concomitant pancreatic exocrine insufficiency among individuals with prediabetes alone and diabetes mellitus alone was 41%(95%CI:12%-75%)and 39%(95%CI:28%-51%),respectively.Further analysis showed that the prevalence of concomitant pancreatic exocrine insufficiency in individuals with prediabetes or diabetes decreases over time after an attack of acute pancreatitis.CONCLUSION:Pancreatic exocrine insufficiency occurs in 40%of individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.Further studies are needed to investigate the pathogenesis of diabetes in this setting.Stephanie L M Das James I C Kennedy Rinki Murphy Anthony R J Phillips John A Windsor Maxim S Petrov 2014World Journal of Gastroenterology2014,20,45:9
2Multidisciplinary prac- tical guidelines for gastrointestinal access for enteral nutrition and decompression from the Society of Interventional Radiology and American Gastroenterological Association ( AGA ) Institute, with endorsement by Canadian Interventional Radiological Association (CIRA) and Cardiovascular and Interventional Radiological Socie- ty of Europe(CIRSE) 显示文摘MAXIM I MARK H D JOHN C F 2011J Vasc Interv Radiol2011,22,8:1
3Leaching of copper and zinc from copper converter slag flotation tailings using H2 SO4 and bio- logically generated Fez (SO4)3 显示文摘Maxim I Muravyov 2012Hydrometallurgy2012,,:1
4Partitioning of polycyclicaromatic hydrocarbons (PAH) to water-soluble soil organic matter显示文摘MAXIM C R KOGEL-KNABNER I 1995EurJ Soil Sci1995,46,:1
5Verolog: A modeling of radiation-induced mismatch enhancement显示文摘MAXIMS G IGOR A D GENNADY I Z 2011IEEE Transactions on Nuclear Science2011,58,3:1
6Quo Vadis, pragmatics? Alternative conceptions in making sense of a heterogeneous discipline (Re- view)显示文摘Stamenov Maxim I 2003Journal of Pragmatics2003,35,:1
7Leaching of copper and zinc from copper converter slag flotation tailings using H2 SO4 and bio- logically generated Fe2 (SO4)3 显示文摘Maxim I Muravyov 2012Hydrometallurgy2012,,:1
8Multidisciplinary practical guidelines for gastrointestinal access for enteral nutrition and decompression from the Society of Interventional Radiology and American Gastroenterological Association(AGA) Institute, with endorsement by Canadian Interventional Radiological Association (CIRA) and Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 显示文摘Maxim I Mark HD John CF 2011J Vasc Interv Radiol2011,22,:1
9Preparation and structure of K2 · 4H2O; a complex of Nb( V ) with a novel anti- { Nbo2 (μ-OH )2 } 4+ core显示文摘MAXIM S HIDEO I TARO S 2000Inorganic Chemistry Communications2000,3,3:1
10Quo Vadis, pragmatics? Alternative conceptions in making sense of a heterogeneous dis- cipline (Review) 显示文摘Stamenov Maxim I 2003Journal of Pragmatics2003,,35:1
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