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| 1 | Four-year follow-up of endoscopic gastroplication for the treatment of gastroesophageal reflux disease显示文摘AIM:To evaluate the long-term effect of Endocinch treatment for gastroesophageal reflux disease(GERD).METHODS:After unblinding and crossover,50 patients(32 males,18 females; mean age 46 years) with pH-proven chronic GERD were recruited from an initial randomized,placebo-controlled,single-center study,and included in the present prospective open-label follow-up study.Initially,three gastroplications using the Endocinch device were placed under deep sedation in a standardized manner.Optional retreatment was offered in the first year with 1 or 2 extra gastroplications.At baseline,3 mo after(re) treatment and yearly proton pump inhibitor(PPI) use,GERD symptoms,quality of life(QoL) scores,adverse events and treatment failures(defined as:patients using > 50% of their baseline PPI dose or receiving alternative antireflux therapy) were assessed.Intention-to-treat analysis was performed.RESULTS:Median follow-up was 48 mo [interquartile range(IQR):38-52].Three patients were lost to follow-up.In 44% of patients retreatment was done after a median of 4 mo(IQR:3-8).No serious adverse events occurred.At the end of follow-up,symptom scores and4 out of 6 QoL subscales were improved(all P < 0.01compared to baseline).However,80% of patients required PPIs for their GERD symptoms.Ultimately,64% of patients were classified as treatment failures.In 60% a post-procedural endoscopy was carried out,of which in 16% reflux esophagitis was diagnosed.CONCLUSION:In the 4-year follow-up period,the subset of GERD patients that benefit from endoscopic gastroplication kept declining gradually,nearly half opted for retreatment and 80% required PPIs eventually. | Matthijs P Schwartz J Rieneke C Schreinemakers André J P M Smout | 2013 | World Journal of Gastrointestinal Pharmacology and Therapeutics2013，4，4： | 4 |
| 2 | Deletion of thy- roid transcription factor-1 gene in an infant with neonatal thyroid dysfunction and respiratory failure 显示文摘 | Devriendt K Vanhole C Matthijs G | 1998 | N Engl J Med1998，338，18： | 1 |
| 3 | Genomic, genetic and structural analysis of pyoverdine mediated iron acquisition in the plant growth-promoting bacterium Pseudomonas fluorescens SBW25显示文摘 | Moon C D Rainey P B Matthijs S | 2008 | BMC Microbiology2008，8，： | 1 |
| 4 | HapX-mediated iron homeostasis is essential forrhizosphere competence and virulence of the soilbornepathogen Fusarium oxysporum显示文摘 | López-Berges MS Capilla J Turrà D Schafferer L Matthijs S J?chl C Cornelis P Guarro J Haas H PietroAD | 2012 | Plant Cell2012，24，38： | 1 |
| 5 | Detecting the phosphate status of phytoplankton by enzyme-labelled fluorescence and flow cytometry显示文摘 | Dignum M Hoogveld H Matthijs H C P | | 0，，： | 1 |
| 6 | Inhibition of lipolysis in bovine adipose tissue by buturate and 13 hydroxybutyrate显示文摘 | Stef H M M Matthijs L C Simon G V B | 1974 | FEBS Lett1974，47，1： | 1 |
| 7 | Exposure of the Cyanobacterium Synechocystis PCC 6803 to salt stress induces concerted changes in respiration and photosynthesis显示文摘 | Matthijs H C P Onana B | 1993 | Plant cell Physical1993，34，： | 1 |
| 8 | Detectingthe phosphate status of phytoplankton by enzyme-labelledfluorescence and flow cytometry显示文摘 | Dignum M Hoogveld H Matthijs H C P | 2004 | FEMS Microbiologi-cal Ecology2004，48，： | 1 |
| 9 | Application of light-emitting diodes in bioreactors:Flashing light effects and energy economy in algal culture(Chlorella pyrenoidosa)显示文摘 | Matthijs H C Balke H Van Hes U M | 1996 | Biotechnology and Bioengineering1996，50，1： | 1 |
| 10 | Exposure of the cyanobacterium Synechocystis PCC6803 to salt induces concerted changes in respiration and photosynthesis显示文摘 | Jeanjean R Matthijs H C P Onana B | 1993 | Plant Cell Physiol1993，，34： | 1 |
| 11 | Epidemiology,diagnosis,and an-timicrobial treatment of acute bacterial meningitis 显示文摘 | Matthijs C Brouwer L Allan R el al | 2010 | Clin Microbiol2010，23，3： | 1 |
| 12 | Cryopreservation of boar semen:equilibrium freezing in the cryomicroscope and in straws显示文摘 | Woelders H Matthijs A Zuidberg C A | 2005 | Theriogenology2005，63，： | 1 |
| 13 | Nitrogen fixation and respiratory electron transport in the cyanobacteriumCyanothece under different light/dark cycles 显示文摘 | Rabouille S Van de Waal D B Matthijs H C P | 2014 | FemsMicrobiology Ecology2014，87，3： | 1 |
| 14 | Principles of the light-limited chemostat:theory and ecological applications显示文摘 | HUISMAN J MATTHIJS H C P VISSER P M | 2002 | Antonie Van Leeuwenhoek2002，81，： | 1 |
| 15 | The role of water retaining substrata on the photosynthetic response of threedrought tolerant phototrophic micro-organisms isolated from a terrestrial habitat显示文摘 | De Winder B Matthijs H C P Mur L R | 1989 | Archives of Microbiology1989，152，： | 1 |
| 16 | Familial temporal lobe epilepsy with febrile seizures显示文摘 | Depondt C Van Paesschen W Matthijs G | 2002 | Neurology2002，58，9： | 1 |
| 17 | Molecular resolution imaging of dextran monolayers immobilized on silica by atomic force microscopy 显示文摘 | Tasker S Matthijs G Davies M C | 1996 | Langmuir1996，12，： | 1 |
| 18 | Cryopreserva- tion of boar semen : equilibrium freezing in the cryomicroscope and in Straws显示文摘 | WOELDERS H MATTHIJS A ZUIDBERG C A | 2005 | Theriogenology2005，63，2： | 1 |
| 19 | Cryopreservation of boar semen : equilibrium freezing in the cryomicroscope and in straws显示文摘 | Woelders H Matthijs A Zuidberg C A | 2005 | Theriogenology2005，63，2： | 1 |
| 20 | Definition and system implementation of strategies for method development of chiral separations in normal- or reversed-phase liquid chromatography using polysaccharide-based stationary phases显示文摘 | Matthijs N Perrin C Maftouh M | 2004 | J Chromatogr A2004，1041，12： | 1 |
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