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| 1 | 非胰岛素依赖型糖尿病冠状动脉疾病的危险因素:英国糖尿病前瞻性研究(UKPDS:23)显示文摘目的:评价2型糖尿病患者冠状动脉疾病的基线危险因素。设计:对2 693例资料完整的患者进行年龄和性别调整的逐步选择过程分析,以确定哪些冠状动脉疾病的危险因素应纳入 Cox 比例风险模型。对象:3 055例白人患者,平均年龄52岁,均新近诊断为2型糖尿病,且无动脉粥样硬化相关疾病的证据。平均随访期7.9年。335例患者于10年内出现冠状动脉疾病。结局评定:具有明确异常心电图的心绞痛、致死或非致死性心肌梗塞。结果:冠状动脉疾病与低密度脂蛋白胆固醇浓度升高、高密度脂蛋白胆固醇浓度降低、甘油三酯浓度升高、高血红蛋白 A_(1c)、高收缩压、高空腹血糖以及吸烟史密切相关。低密度脂蛋白胆固醇较高1/3对较低1/3区间的估计风险比为2.26(95%可信区间为1.70~3.00),高密度脂蛋白胆固醇为0.55(0.41~0.73),血红蛋白 A_(1c)为1.52(1.15~2.01),收缩压为1.82(1.34~2.47)。吸烟者的估计风险比为1.41(1.06~1.88)。结论:2型糖尿病患者中,存在冠状动脉疾病潜在的、可变的5种危险因素的交叉重叠影响。它们是低密度脂蛋白胆固醇浓度升高、高密度脂蛋白胆固醇浓度降低、高血压、高血糖和吸烟。 | R C Turner H Millns H A W Neil I M Stratton S E Manley D R Matthews R R Holman 赵维纲 | 1998 | 英国医学杂志中文版1998，0，3： | 11 |
| 2 | Structural basis for blocking PD-l-mediated immune suppression by therapeutic antibody pembrolizumab显示文摘 | Zhenkun Na Siok Ping Yeo Sakshibeedu R Bharath Matthew W Bowler Esra Ballkci Cheng-I Wang Haiwei Song | 2017 | Cell Research2017，27，1： | 10 |
| 3 | Nat Genet:单基因突变导致过敏性皮炎的发生显示文摘最近,研究者们鉴定出了一类导致神经性皮炎发生的关键基因突变:CARDll。来自美国NIH过敏与传染病研究所的研究者们通过对四个没有血缘关系的患病家庭进行分析,发现了这一导致疾病产生的基因、 | Chi A Ma, Yuan Zhang, Michael A Weinreich, Jonathan J Lyons, Celeste G Nelson, Thomas DiMaggio, Kelly D Stone, Joshua D Milner Jeffrey R Stinson, Elisa Ruffo, Batsukh Dorjbal, Swadhinya Arjunaraja, Kelsey Voss, Andrew L Snow Jordan K Abbott, Pia J Hauk, Paul R Reynolds, Erwin W Gelfand Elisa Ruffo Salomé Glauzy, Natsuko Yamakawa, Eric Meffre Jennifer Stoddard, Julie Niemela, Sergio D Rosenzweig Yu Zhang, Helen F Matthews Joshua J McElwee Nina Jones Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, Silvia Danielian, Jonathan Zaiat, Marcelo A Marti Brian Kim Megan A Cooper Neil Romberg | 2017 | 现代生物医学进展2017，17，27： | 3 |
| 4 | Factors influencing mercury accumulation in three species of forage fish from Caddo Lake, Texas, USA显示文摘Most studies that have examined mercury (Hg) contamination of fish have focused on game species feeding near the top of the food web, while studies that examine forage fish that feed near the base of the food web are rare. We conducted a survey of Hg contamination in three species of forage fish, brook silverside (Labidesthes sicculus), threadfin shad (Dorosoma petenense) and gizzard shad (Dorosoma cepedianum), from Caddo Lake, Texas, USA and found species-specific differences in Hg concentrations. We examined total length, age, trophic position (determined using δ15N), and growth rate of forage fish as factors that could have influenced within-and between-species differences in Hg concentration. Total length and age were the best predictors of within-species differences in Hg concentration. Between-species differences in Hg concentrations were most strongly influenced by trophic position. | Matthew M Chumchal Ray W Drenner David R Cross K David Hambright | 2010 | Journal of Environmental Sciences2010，22，8： | 3 |
| 5 | Formation of nitrate and ammonium-ions in titanium-dioxide mediated photocatalytic degradation of organic-compounds compounds containing nitrogen-atoms 显示文摘 | McEvoy S R Matthews R W 1991 | 1991 | Environ Sci Technol1991，25，： | 1 |
| 6 | Recent advances of laser-spectroscopy based techniques for applications in breath analysis 显示文摘 | Matthew R M Yury B Gerard W | 2007 | J Breath Res2007，1，1： | 1 |
| 7 | Examining the relation between ethical focus and fi-nancial performance in family firms:an exploratory study显示文摘 | O BOYLE E H MATTHEW W R POLLACK J M | | 0，，04： | 1 |
| 8 | Peripheral neuropathy and the risk of cardio- vascularevents in type 2 diabetes mellitus显示文摘 | Jack R W Brownrigg Matthew M Thompson 1 Kausik K Ray | 2014 | Cardiac risk factors and prevention2014，，100： | 1 |
| 9 | Anisotropic effects on the strain rate dependence of a wrought magnesium alloy 显示文摘 | MATTHEW T T MARK F H PHILLIP M G HAITHAM E K WILBURN R W | 2009 | Scripta Materialia2009，60，： | 1 |
| 10 | Photooxidation of organic impurities in water u- sing thin films of titanium dioxide显示文摘 | Matthews R W | 1987 | Journal of Physical Chemis- try1987，91，12： | 1 |
| 11 | Modelling China's potential maize production at regional scale under climate change显示文摘 | Xiong W Matthews R Holman I | 2007 | Climatic Change2007，85，： | 1 |
| 12 | Review of the pest sta- tus and control options for Thrips palmi显示文摘 | Cannon R J C Matthews L Collins A D W | 2007 | Crop Protection2007，26，8： | 1 |
| 13 | Near shortest and k-shortest simple paths显示文摘 | MATTHEW W CARLYLE R KEVIN W | 2005 | Networks2005，46，2： | 1 |
| 14 | Flow-injection detertion of organic contaminants in water using an ultraviolet-me- diated titanium dioxide film reactor显示文摘 | Gary K C Low Matthews R W | 1990 | Analytica Chimica Acta1990，231，： | 1 |
| 15 | Examination of glial and neurona] hanges in the nucleus basalis of Meynert in schizophrenia and re- current depression 显示文摘 | Matthew W Marsh R Jain J | 2011 | Int Clin Psychopharmacol2011，26，12： | 1 |
| 16 | Controlled manipulation of molecular samples with the nanomanipulator 显示文摘 | M Guthold M R Falvo W G Matthews Swashbttrn S Paulson D A Erie | 2000 | IEEE/ASME Transactions on Mechatronies (S1083-4435)2000，5，2： | 1 |
| 17 | Planar functions and planes of Lenz-Barlotti class Ⅱ显示文摘 | COULTER R S MATTHEWS R W | 1997 | Design Coding and Cryptography1997，10，2： | 1 |
| 18 | Kinetics of photocatalytic oxidation of organic solutes over titanium dioxide 显示文摘 | Matthews R W | 1988 | Journal of Catalysis1988，111，2： | 1 |
| 19 | A new species of Nitela (Hymenoptera: Sphecidae: Larrinae ) from Australia with notes on the nests and prey of two species 显示文摘 | Matthews R W | 2000 | Journal of Hymenoptera Research2000，9，： | 1 |
| 20 | The layered and historical nature of ecological systems and the risk assessment ofpesticides显示文摘 | Landis W G Matthews R A Matthews G B | 1996 | Environ Toxicol Chem1996，15，： | 1 |
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