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15篇 您的检索式：作者名="Matthews IS"

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		题名	作者	年代	出处	被引量
	1	How location and cellular signaling combine to activate the NLRP3 inflammasome显示文摘NOD-,LRR-,and pyrin domain-containing 3(NLRP3)is a cytosolic innate immune sensor of cellular stress signals,triggered by infection and sterile inflammation.Upon detection of an activating stimulus,NLRP3 transitions from an inactive homo-oligomeric multimer into an active multimeric inflammasome,which promotes the helical oligomeric assembly of the adaptor molecule ASC.ASC oligomers provide a platform for caspase-1 activation,leading to the proteolytic cleavage and activation of proinflammatory cytokines in the IL-1 family and gasdermin D,which can induce a lytic form of cell death.Recent studies investigating both the cellular requirement for NLRP3 activation and the structure of NLRP3 have revealed the complex regulation of NLRP3 and the multiple steps involved in its activation.This review presents a perspective on the biochemical and cellular processes controlling the assembly of the NLRP3 inflammasome with particular emphasis on structural regulation and the role of organelles.We also highlight the latest research on metabolic control of this inflammatory pathway and discuss promising clinical targets for intervention.	Anil Akbal Alesja Dernst Marta Lovotti Matthew S.J.Mangan Róisín M.McManus Eicke Latz	2022	Cellular & Molecular Immunology2022，19，11：	2
	2	Variability and classification accuracy of serial high- sensitivity C -reactive protein measurements in healthy adults显示文摘	Ockene IS Matthews CE Rifai N	2001	Clinical Chemistry2001，47，3：	1
	3	Variability and classification accuracy of serial high-sensitity C reactive proteim measurements in healthy adults显示文摘	Ockene IS Matthews CE Rifai N	2001	Clin Chem2001，47，3：	1
	4	Variability and classification accu- racy of serial high-sensitivity C-reactive protein measurements in healthy a- duhs显示文摘	Ockene IS Matthews CE Rifai N	2001	Clin Chem2001，47，3：	1
	5	Temperature measured in human cortical bone when drilling显示文摘	Matthews IS Hirsch C	1972	J Bone Joint SurgAm1972，54，2：	1
	6	Variability and cassification accuracy of serial high-sensitivity C-reactive protein measurements in healthy adults显示文摘	Ockene IS Matthews CE Rifai N	2001	Clin Chem2001，47，3：	1
	7	Variability and cassification accuracy of serial high-sensitivity C-reactive protein measurements in healthy adults 显示文摘	Ockene IS Matthews CE Rifai N	2001	Clinical Chemistry2001，47，3：	1
	8	Leg injuries 显示文摘	Blue JM Matthews IS	1997	Clin Sports Med1997，16，3：	1
	9	Variability and cassifieation accuracy of serial highsensitivity Creactive protein measurements in healthy adults显示文摘	Ockene IS Matthews CE Rifai N	2001	Clin Chem2001，47，3：	1
	10	Oral decontamination with chlorhexi-dine reduces the incidence of nosocomial pneumonia显示文摘	Ilias IS Matthew EF	2007	Criti-cal Care2007，11，1：	1
	11	Variability and classification accuracy of serial high - sensitivity C - reactive protein measurements in healthy adults显示文摘	Ockene IS Matthews CE Rifai N	2001	Clin Chem2001，47，3：	1
	12	Variability and cassification accuracy of serial high-sensitivity C-reactive protein measurements in healthy adults显示文摘	Ockene IS Matthews CE Rifai N	2001	Clin Chem2001，47，3：	1
	13	Optimal side plate fixation for unstable intertrochanteric hip fractures 显示文摘	Yian EH Banerji I Matthews IS	1997	J Orthop Trauma1997，11，4：	1
	14	Variability and classification accuracy of serial high sensitivity C reactive protein measurements in healthy adults 显示文摘	Ockene IS Matthews CE Raffia N	2001	Clin Chemistry2001，47，3：	1
	15	Wariability and Clarification accuracy of serial high-sensitivity C-reactive protein measurements in healthy adults显示文摘	Ockene Is Matthews CE Rifai N	2001	Clinical Chemistry2001，47，：	1

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