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| 1 | Drain amylase value as an early predictor of pancreatic fistula after cephalic duodenopancreatectomy显示文摘AIM:To determine predictors of clinically relevant pancreatic fistulas(CRPF)by measuring drain fluid amylase(DFA)in the early postoperative period.METHODS:This prospective clinical study included382 patients with periampullary tumors that were surgically resected at our department between March 2005and October 2012.A cephalic duodenopancreatectomy (DP)was performed on all patients.Two closed suction drains were placed at the end of the surgery.The highest postoperative DFA value was recorded and analyzed during the first three postoperative days and on subsequent days if the drains were kept longer.Pancreatic fistula(PF)was classified according to the International Study Group of Pancreatic Fistula(ISGPF)criteria.Postoperative complications were defined according to the Dindo-Clavien classification.All data were statistically analyzed.The optimal thresholds of DFA levels on the first,second and third postoperative days were estimated by constructing receiver operating curves,generated by calculating the sensitivities and specificities of the DFA levels.The DFA level limits were used to differentiate between the group without PF and the groups with biochemical pancreatic fistula(BPF)and CRPF.RESULTS:Pylorus-preserving duodenopancreatectomy was performed on 289(75.6%)patients,while the remaining patients underwent a classic Whipple procedure(CW).The total incidence of PF was 37.7%(grade A22.8%,grade B 11.0%and grade C 3.9%).Soft pancreatic texture(SPT)was present in 58.3%of patients who developed PF.Mortality was 4.2%.The median DFA value on the first postoperative day(DFA1)in patients who developed PF was 4520 U/L(range 350-99000 U/L)for grade A fistula(BPF)with a SPT and a diameter of the main pancreatic duct(MPD)of≤3 mm.For grade B/C(CRPF),the median DFA1 value was 8501 U/L(range377-92060 U/L)with a SPT and MPD of≤3 mm.These values were significantly higher when compared to the patients who did not have PF(122;range 5-37875 U/L).The upper limit of DFA values for the first 3 postoperative days in the examined stages of PF were:DFA1 1200U/L for the BPF and CRPF;DFA3 350 U/L for BPF and DFA3 800 U/L for CRPF.The determined values were highly significant and demonstrated a reliable diagnostic test for both BPF and CRPF.CONCLUSION:DFA1≥1200 U/L is an important predictive factor for PF of any degree.The trend of DFA3(decrease of<50%)compared to DFA1 is a significant factor in the differentiation of CRPF from transient BPF. | Vladimir D Dugalic Djordje M Knezevic Vladan N Obradovic Miroslava G Gojnic-Dugalic Slavko V Matic Aleksandra R Pavlovic-Markovic Predrag D Dugalic Srbislav M Knezevic | 2014 | World Journal of Gastroenterology2014，20，26： | 7 |
| 2 | The anatomy of temporal hollowing: the superficial temporal fat pad 显示文摘 | KIM S MATIC D B | 2005 | J Craniofac Surg2005，16，5： | 1 |
| 3 | Chronic obstructive pulmonary disease and weaning of difficult-to-wean patients from mechanical ventilation:randomized prospective study显示文摘 | Matic I Danic D Majeric-Kogler V | 2007 | Croat Med J2007，8，1： | 1 |
| 4 | Necrotizing fasciitis : literature review of contemporary strategies for diagnosing and management with three case reports : torso, abdominal wall, upper and lower limbs显示文摘 | Roje Z Roje Z Matic D | 2011 | World J Emerg Surg2011，6，： | 1 |
| 5 | Three cases of C- ANCA-positive vasculitis treated with immunoadsorption: possible benefit in early treatment显示文摘 | Matic G Michelsen A Hofmann D | 2001 | Ther Apher2001，5，1： | 1 |
| 6 | Acute myocardial infarction following a hornet sting 显示文摘 | Cvetkovic-Matic D Asanin M Matic D | 2009 | Vojnosanit Pregl2009，66，4： | 1 |
| 7 | A novel direct torque control and flux control algorithm for the induction motor drive 显示文摘 | Matic P R Blanusa B D Bukesavic S N | 2003 | Electric Machine and Drives2003，2，3： | 1 |
| 8 | Chronic ob- structive pulmonary disease and weaning of difficult-to- wean patients from mechanical ventilation: randomized prospective study显示文摘 | Matic I Danic D Majeric-Kogler V | 2007 | Croat Med J2007，48，1： | 1 |
| 9 | The Anatomy of Temporal Hallowing:The Superficial Temporal Fat Pad显示文摘 | Kim S Matic D | 2005 | Journal of Craniofecial Surgery2005，16，5： | 1 |
| 10 | Chronic obstructive pulmonary disease and weaning of difficult to wean patients from mechanical ventilation : randomized prospective study显示文摘 | Matic I Danic D Majeric Kogler V | 2007 | Croat Med J2007，48，1： | 1 |
| 11 | Cytokines in patho- genesis of peri-implantitis 显示文摘 | Petkovic-Curcin A Matic S Vojvodic D | 2011 | Vojnosanit Pregl2011，68，5： | 1 |
| 12 | Influence of silicone oil tampo- nade after vitrectomy on intraocular pressure 显示文摘 | Matic S Suic SP Biuk D | 2013 | Cull Antropol2013，37，： | 1 |
| 13 | Temporal hollowing following coronal inchsion:a prospective, randomized, controlled trial 显示文摘 | Matic D B Kim S | 2008 | Plast Reconst r Surg2008，121，： | 1 |
| 14 | Necrotizing fasciitis : litera- ture review of contemporary strategies for diagnosing and management with three case reports: torso, abdominal wall, upper and lower limbs显示文摘 | Roje Z Roj e Z Matic D | 2011 | World J Emerg Surg2011，6，1： | 1 |
| 15 | Data access architecture in object oriented applications using design patterns显示文摘 | Matic D Butorac D Kegalj H | 2004 | IEEE2004，2，： | 1 |
| 16 | Synthesis and characterization of a lactic acid-based thermoset resin suitable for structural composites and coatings显示文摘 | (A)kesson D Skrifvars M Sepp(a)l(a) J Turunen M Martinelli A Matic A | 2010 | Journal of Applied Polymer Science2010，115，1： | 1 |
| 17 | Chronic obstructivepulmonary disease and weaning of difficult - to - wean patientsfrom mechanical eventilation: randomized prospective study 显示文摘 | Matic I Danic D Majeric - Kogler V | 2007 | Croat Med2007，48，1： | 1 |
| 18 | Correction of the cleft lip lateral bulge deformity using anatomic muscle repair显示文摘 | Matic D B Power S M | 2011 | J Craniofac Surg2011，22，2： | 1 |
| 19 | Acute myocardial infarction following a hornet sting显示文摘 | Cvetkovic'-Matic' D Asanin M Matic' D | 2009 | Vojnosanit Pregl2009，66，4： | 1 |
| 20 | Gingivoperiosteoplasty following alveolar molding with a Latham appliance versus secondary bone grafting: the effects on bone production and midfacial growth in patients with bilateral clefts显示文摘 | POWER S M MATIC D B | 2009 | Plast Reconstr Surg2009，124，2： | 1 |
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