|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Viral hepatitis update: Progress and perspectives显示文摘Viral hepatitis,secondary to infection with hepatitis A,B,C,D,and E viruses,are a major public health problem and an important cause of morbidity and mortality.Despite the huge medical advances achieved in recent years,there are still points of conflict concerning the pathogenesis,immune response,development of new and more effective vaccines,therapies,and treatment.This review focuses on the most important research topics that deal with issues that are currently being solved,those that remain to be solved,and future research directions.For hepatitis A virus we will address epidemiology,molecular surveillance,new susceptible populations as well as environmental and food detections.In the case of hepatitis B virus,we will discuss host factors related to disease,diagnosis,therapy,and vaccine improvement.On hepatitis C virus,we will focus on pathogenesis,immune response,direct action antivirals treatment in the context of solid organ transplantation,issues related to hepatocellular carcinoma development,direct action antivirals resistance due to selection of resistanceassociated variants,and vaccination.Regarding hepatitis D virus,we describe diagnostic methodology,pathogenesis,and therapy.Finally,for hepatitis E virus,we will address epidemiology(including new emerging species),diagnosis,clinical aspects,treatment,the development of a vaccine,and environmental surveillance. | María B Pisano Cecilia G Giadans Diego M Flichman Viviana E Ré María V Preciado Pamela Valva | 2021 | World Journal of Gastroenterology2021，27，26： | 8 |
| 2 | Effects of cellulase and xylanase enzymes mixed with increasing doses of Salix babylonica extract on in vitro rumen gas production kinetics of a mixture of corn silage with concentrate显示文摘An in vitro gas production(GP) technique was used to investigate the effects of combining different doses of Salix babylonica extract(SB) with exogenous fibrolytic enzymes(EZ) based on xylanase(X) and cellulase(C), or their mixture(XC; 1:1 v/v) on in vitro fermentation characteristics of a total mixed ration of corn silage and concentrate mixture(50:50, w/w) as substrate. Four levels of SB(0, 0.6, 1.2 and 1.8 m L g–1 dry matter(DM)) and four supplemental styles of EZ(1 μL g–1 DM; control(no enzymes), X, C and XC(1:1, v/v) were used in a 4×4 factorial arrangement. In vitro GP(m L g–1 DM) were recorded at 2, 4, 6, 8, 10, 12, 24, 36, 48 and 72 h of incubation. After 72 h, the incubation process was stopped and supernatant p H was determined, and then filtered to determine dry matter degradability(DMD). Fermentation parameters, such as the 24 h gas yield(GY24), in vitro organic matter digestibility(OMD), metabolizable energy(ME), short chain fatty acid concentrations(SCFA), and microbial crude protein production(MCP) were also estimated. Results indicated that there was a SB?EZ interaction(P<0.0001) for the asymptotic gas production(b), the rate of gas production(c), GP from 6 to 72 h, GP2(P=0.0095), and GP4(P=0.02). The SB and different combination of enzymes supplementation influenced(P<0.001) in vitro GP parameters after 12 h of incubation; the highest doses of SB(i.e., 1.8 m L g–1 DM), in the absence of any EZ, quadratically increased(P<0.05) the initial delay before GP begins(L) and GP at different incubation times, with lowering b(quadratic effect, P<0.0001) and c(quadratic effect, P<0.0001; linear effect, P=0.0018). The GP was the lowest(P<0.05) when the highest SB level was combined with cellulose. There were SB?EZ interactions(P<0.001) for OMD, ME, the partitioning factor at 72 h of incubation(PF72), GY24, SCFA, MCP(P=0.0143), and p H(P=0.0008). The OMD, ME, GY24 and SCFA with supp lementation of SB extract at 1.8 m L g–1 DM were higher(P<0.001) than the other treatments, however,PF72 was lower(quadratic effect, P=0.0194) than the other levels. Both C and X had no effect(P>0.05) on OMD, p H, ME, GY24, SCFA and MP. The combination of SB with EZ increased(P<0.001) OMD, ME, SCFA, PF72 and GP24, whereas there was no impact on p H. It could be concluded that addition of SB extract, C, and X effectively improved the in vitro rumen fermentation, and the combination of enzyme with SB extract at the level of 1.2 m L g–1 was more effective than the other treatments. | Abdelfattah Z M Salem German Buendía-Rodríguez Mona M M Elghandour María A Mariezcurrena Berasain Francisco J Pea Jiménez Alberto B Pliego Juan C V Chagoyán María A Cerrillo Miguel A Rodríguez | 2015 | Journal of Integrative Agriculture2015，14，1： | 4 |
| 3 | A multi-ob-jective model for locating fire stations 显示文摘 | MASOOD A B MAR K M COLONEL A A | 1998 | European Jour-nal of Operational Research1998，110，： | 1 |
| 4 | The effects of high CO2levels on anthocyanin composition,antioxidant activity and soluble sugar content of strawberries stored at low non-freezing temperature显示文摘 | Oscar G B María B María T S | 2010 | Food Chemistry2010，122，3： | 1 |
| 5 | The flooding time synchro- nization protocol 显示文摘 | MAR(')TI M KUSY B | 2004 | 2nd International Confer- ence on Embedded Networked Sensor Systems Baltimore MD USA2004，2004，： | 1 |
| 6 | Fish Classification Based on Robust Features Extraction From Color Signature Using BackPropagation Classifier显示文摘 | Alsmadi Mutasem K mar Khairuddin B Noah Shahrul A.M | | 0，，： | 1 |
| 7 | DNA Fingerprint Comparison of rainbow Trout and RTG-2 Cell Line Using Random Amplified Polymorphic DNA显示文摘 | Concepcion B Helda A Mar F | 2001 | Ecotoxicology2001，10，： | 1 |
| 8 | Systematic re- view of perioperative and quality of-life outcomes fol lowing surgical management of localised renal cancer 显示文摘 | MaeLennan S Imamura M Lapitan M C ()mar M I Lain T B Hilvano-Cabungcal A M | 2012 | Eur Urol2012，62，： | 1 |
| 9 | Serum paraoxonase and arylesterase activates in Patients with lung cancer in a Turkish population 显示文摘 | Elkiran ET Mar N Aygen B | 2007 | BMC Cancer2007，7，： | 1 |
| 10 | Freshwater phytoplankton quantification by chlorophyll a:a comparative study of in vitro,in vivo and in situ methods显示文摘 | Gregor J Mar(s)(a)lek B | 2004 | Water Research2004，38，： | 1 |
| 11 | A survey of bondgraphs : theory, applications and programs 显示文摘 | JENNY M D MAR/SOL D CLAUDE B | 1991 | Journal of the Franklin Institute1991，328，： | 1 |
| 12 | Pollutant loading model fo- rhighway runoff 显示文摘 | Chui T W Mar B W Homer R R | 1982 | Journal of Environmental Engineering1982，108，6： | 1 |
| 13 | Control and prevention of gas and outbursts in coal mines,Riosa-Olloniego coalfield,Spain显示文摘 | María B Díaz Aguado C González Nicieza | 2007 | International Journal of Coal Geology2007，69，4： | 1 |
| 14 | Serum paraoxonase and arylesterase activities in patients with lung cancer in a T urkish population显示文摘 | Elkiran ET Mar N Aygen B | 2007 | BMC Cancer2007，7，1： | 1 |
| 15 | Review on thermal energy storage with phase change:Materials,heat transfer analysis and applications显示文摘 | Zalba B Mar?n J M Cabeza L F | 2003 | Applied Thermal Engineering2003，23，： | 1 |
| 16 | Progress in the development of animal models of acute kidney injury and its impact on drug discovery显示文摘 | Ana B Sanz Marí a Dolores Sanchez-Ni? o Catalina Martí n-Cleary Alberto Ortiz Adriá n M Ramos | 2013 | Expert Opinion on Drug Discovery2013，，7： | 1 |
| 17 | Crystal structure and DNA interaction of the facial-type rac-tris[2-(aminomethyl) benzimidazole] cobalt(Ⅲ) complex显示文摘 | JORDI G S MARíA J P MERCèF B | | 0，，25： | 1 |
| 18 | Isolation, chemical investigation and antiviral activity of polysaccharides from Gracilaria corticata (Gracilariaceae, Rhodophyta)显示文摘 | Sutapa Mazumder Prodyut K Ghosal Carlos A Pujol Mar??a J Carlucci Elsa B Damonte Bimalendu Ray | 2002 | International Journal of Biological Macromolecules2002，，1： | 1 |
| 19 | 查看详情显示文摘 | María L G P Patricia P B Roberto R G José L M V Antonia G F | | 0，，27： | 1 |
| 20 | Characterisation andphotocatalytic properties of titania-silica mixed oxides doped withAg and Pt显示文摘 | Llano B Restrepo G Marín J M | 2010 | Applied Catalysis A:General2010，387，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员