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| 1 | Continued increase in the prevalence of asthma and atopy 显示文摘 | Downs SH Marks GB Sporik R | 2001 | Arch Dis Child2001，84，1： | 1 |
| 2 | Continued increase in theprevalence of asthma and atopy显示文摘 | Downs SH Marks GB Sporik R | 2001 | Arch Dis Child2001，84，1： | 1 |
| 3 | Continued increase in the prevalence of asthma and atopy显示文摘 | Downs SH Marks GB Sporik R et aI | 2001 | Arch Dis Child2001，84，1： | 1 |
| 4 | Having lived on a farm and protection against allergic diseases in Australia显示文摘 | DOWNS S H MARKS G B MITAKAKIS T Z | 2001 | Clin Exp Allergy2001，31，： | 1 |
| 5 | Having lived on a farm and protection against allergic diseases in Australia显示文摘 | Downs SH Marks GB Mitakakis TZ | 2001 | Clin Exp Allergy2001，31，5： | 1 |
| 6 | Having lived on a farm and protection against allergic diseases in Australia显示文摘 | Downs SH Marks GB Mitakakis TZ | 2001 | Clin Exp Allergy2001，3，4： | 1 |
| 7 | The metabotropic glutamate receptor subtype 5 mediates sensitivity to the sedative properties of ethanol显示文摘 | Downing C Marks MJ Larson C | | 0，，09： | 1 |
| 8 | Clinical importance of Altemaria exposure in children显示文摘 | Downs S H Mitakakis T Z Marks G B | 2001 | Am J Respir Crit Care Med2001，164，3： | 1 |
| 9 | ContInued Increase In the prevalence of asthma and atrophy显示文摘 | Downs SH Marks GB Spork R | 2001 | A rich D Is Child2001，84，1： | 1 |
| 10 | Continued in- crease in the prevalence of asthma and atopy显示文摘 | DOWNS S H MARKS G B SPORIK R | 2001 | Arch Dis Child2001，84，1： | 1 |
| 11 | Injection-Associated Pain in Femoral Arteriography:A European Multicenter Study Comparing Safety,Tolerability,and Efficacy of Iodixanol and Iopromide显示文摘 | Per Justesen Mark Downes | 1997 | Cardiovase Intervent Radiol1997，20，4： | 1 |
| 12 | Having lived on a farm and protection against allergic diseases in Australia 显示文摘 | Downs SH Marks GB Mitakakis TZ | 2001 | Clin Exp Allergy2001，31，4： | 1 |
| 13 | Continued increase in the prevalence of asthma and atopy显示文摘 | Downs SH Marks GB Sporik R | | 0，，01： | 1 |
| 14 | Clinical importance of Alternaria exposure inchildren显示文摘 | Downs S H Mitakakis T Z Marks G B et aI | 2001 | Am J Respir Crit Care Med2001，164，3： | 1 |
| 15 | Continued increase in the prevalence of asthma and atopy显示文摘 | Downs SH Marks GB Sporik R | 2001 | Arch Dis Child2001，84，1： | 1 |
| 16 | Continued increase in the prevalence of asthma and atopy显示文摘 | Downs SH Marks GB Sponk R et ai | 2001 | Arch Dis Child2001，84，1： | 1 |
| 17 | 无线传感网将驱动物联网发展显示文摘结合无数具有IP功能的装置、RFID标签、无线传感网络、机器对机器(M2M)通信、iPhone手机应用程序、空白电视频段及云端运算,便能够具体实现物联网(IoT,Internet of Things)。 | Mark Downing | 2012 | 电子产品世界2012，19，6： | 1 |
| 18 | Testing the Reliability of the Benefit Function Transfer Approach显示文摘 | Mark Downing Teofilo Ozuna Jr | 1996 | Journal of Environmental Economics and Management1996，，3： | 1 |
| 19 | Renal function after renal artery stenting显示文摘Atherosclerotic renal artery stenosis (ARAS), a common clinical finding, is increasing in prevalence as the population ages. ARAS is seen in ~ 7% of persons over 65 years of age1 and in ~ 20% of patients at the time of coronary angiography.2 It is an important cause of chronic kidney disease and may result in 11-14% of cases of end stage renal disease. | George S.Hanzel Mark Downes Peter A.McCullough | 2005 | Journal of Geriatric Cardiology2005，2，4： | 0 |
| 20 | Impact of extended-infusion piperacillin-tazobactam in a Canadian community hospital显示文摘Background:Studies have demonstrated improved clinical outcomes with extended infusion(EI)piperacillin/tazobactam(TZP)compared to standard infusion(SI).However,there is less evidence on its benefits in noncritically-ill patients.Hospital-wide EI TZP was implemented at our site on February 21,2012.Our objectives were to compare clinical,safety and economic outcomes between EI and SI TZP.Methods:A retrospective cohort study of all adult patients who received EI TZP(3.375 g IV q8h infused over 4 hours and SI TZP for≥48 hours during 3 years pre-and postimplementation was conducted.The primary study outcome was 14-day mortality while secondary outcomes included length of hospital stay(LOS),nursing plus pharmacy cost,occurrence of Clostridioides difficile infection,readmission within 30 days and change in Pseudomonas aeruginosa minimum inhibitory concentration(MIC)distribution for TZP.The primary outcome and binary secondary outcomes were analyzed using a logistic regression model.LOS was examined using time to event analysis.Cost was examined using linear regression modelling.Results:Overall,2034 patients received EI TZP and 1364 patients received SI TZP.EI TZP was associated with lower odds of mortality(OR 0.76,95%CI 0.63-0.91),lower odds of C.difficile infection(OR 0.59,95%CI 0.41-0.84)and 8%lower cost(estimate 0.92,95%CI 0.87-0.98)compared to SI TZP.Conclusions:Hospital-wide implementation of EI TZP was associated with lower odds of 14-day mortality and incidence of C.difficile infection with cost savings at our institution. | April J.Chan Gerald Lebovic Michael Wan Yan Chen Elizabeth Leung Bradley J.Langford Jenny Seah Linda R.Taggart Mark Downing | 2023 | Infectious Medicine2023，2，1： | 0 |
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