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| 1 | A modified iteration perturbation method for some nonlinear oscillation problems 显示文摘 | MARINCA V HERISANU N | 2006 | Acta Mechanic2006,184,1: | 1 |
| 2 | Juxtapapillary duodenal diverticula early and late clinical and therapeutical implications显示文摘 | Straja D Marinca M Alecu M | | 0,,: | 1 |
| 3 | Comments on 'A one-step optimal homotopy analysis method for nonlinear differential equations'显示文摘 | MARINCA V HERISANU N | 2010 | Commun Nonlinear Sci Numer Simulat2010,15,11: | 1 |
| 4 | Age-related prognostic factors and treatment results for advanced non-small cell lung cancer (NSCLC)显示文摘 | Clement D Miron L Marinca M | 2007 | Rev Med Chir Soc Med Nat Iasi2007,111,4: | 1 |
| 5 | A solution for a deterministic QoS in multimedia systems显示文摘 | GEORGE L MARINCA D MINET P | 2000 | International Journal on Computer and Information Science2000,1,3: | 1 |
| 6 | Application of the variational iterationmethod to some nonlinear one dimensional oscillations显示文摘 | V Marinca N Herisanu C Bota | 2008 | Meccani-ca2008,43,1: | 1 |
| 7 | The determination of the linear alkylbenzene sulfonate isomers in water samples by gas-chromatography/mass spectrometry显示文摘 | MOLDOVAN Z AVRAM V MARINCAS O | 2011 | Journal of Chromatography A2011,1218,2: | 1 |
| 8 | Prepara-tion and characterisation of Co-Fe-Ni-M-Si-B ( M = Zr,Ti) a-morphous powders by wet mechanical alloying显示文摘 | Neam爫u B V Chicina爧 H F Marinca T F | 2016 | [3]Journalof Alloys and Compounds2016,673,15: | 1 |
| 9 | Age -related prognostic factors and treatment results for advanced non - small cell lung cancer (NSCLC) 显示文摘 | Clement D Miron L Marinca M | 2007 | Rev Med Chir Soc Med Nat Ia- si2007,111,4: | 1 |
| 10 | Extending indication for radiofrequency ablation (RFA) in cancer surgery显示文摘 | Prunoiu V Cirimbei C Marincas M | 2011 | Chirurgia (Bucur)2011,106,: | 1 |
| 11 | The Determination of the Linear Alkylbenzene Sulfonate Isomers in Water Samples by Gas-Chromatography/Mass Spectrometry 显示文摘 | Moldovan Z Avram V Marincas O | 2011 | J Chromatogr A2011,1218,2: | 1 |
| 12 | Extending indication forradiofrequency ablation (RFA) in cancer surgery 显示文摘 | Prunoiu V Cirimbei C Marincas M | 2011 | Chirurgia (Buc-ur)2011,106,5: | 1 |
| 13 | Postradiotherapy regression-a prognostic factor in rectal neoplasm 显示文摘 | Marincas M Cirimbei C Prunoiu V | 2011 | Chirurgia (Bucur)2011,106,: | 1 |
| 14 | Age-ralated prognostic factors and treatment results for advanced non-small cell lung cancer (NSCLC)显示文摘 | Clement D Miron L Marinca M | 2007 | Roy Med Chit Soc Med Nat Iasi2007,111,4: | 1 |
| 15 | 工程中的非线性动力系统一些近似方法显示文摘在非线性动力系统中,采用带变量系数的非线性微分方程组和线性微分方程组的分析方法非常重要,但是在具有强非线性的非线性系统中这些方法很难解决问题。一般而言,已知的分析方法受限于方程的参数,只适用于弱非线性问题的求解。 | Vasile Marinca(等) 孙伟 | 2013 | 国外科技新书评介2013,,3: | 0 |
| 16 | Oxaliplatin-induced neuropathy and colo-rectal cancer patient's quality of life:Practical lessons from a prospective cross-sectional,real-world study显示文摘BACKGROUND Colon cancer is one the most common forms of cancer in both sexes.Due to important progress in the field of early detection and effective treatment,colon and rectal cancer survivors currently account for 10%of cancer survivors worldwide.However,the effects of anti-cancer treatments,especially oxaliplatinbased chemotherapy,on the quality of life(QoL)have been less evaluated.Although the incidence of severe chemotherapy-induced neuropathy(CIPN)in clinical studies is below 20%,data from real-world studies is scarce,and CIPN is probably under-reported due to patient selection and the patients’fear that reporting side-effects might lead to treatment cessation.AIM To determine the impact of CIPN on QoL in colorectal cancer patients with a recent history of oxaliplatin-based chemotherapy.METHODS We performed a prospective cross-sectional study in two major Romanian oncology tertiary hospitals—the Regional Institute of Oncology Ia?i(Iasi,Romania)and the Fundeni Clinical Oncology Institute(Bucharest,Romania).All consecutive patients with colon or rectal cancer,undergoing Oxaliplatin-based chemotherapy that consented to enroll in the study,were assessed by means of two questionnaires—the EORTC QQ-CR29(quality of life in colon and rectal cancer patients)and the QLQ-CIPN20(assessment of neuropathy).Several demographical,social,clinical and treatment data were also collected.Statistical analysis was performed by means of SPSS v20.The student t test was used to assess the relationship between the QLQ-CIPN20 and QLQ-CR29 results.Kaplan Meyer-curves were used to report 3-year progression-free survival(PFS)in patients that discontinued chemotherapy vs those that completed the recommended course.RESULTS Of the 267 patients that fulfilled the inclusion criteria in the pre-specified time frame,101(37.8%)agreed to participate in the clinical study.At the time of the enrolment in the study,over 50%of the patients had recently interrupted their oxaliplatin-based chemotherapy,most often due to neuropathy.Almost 85%of the responders reported having tingling or numbness in their fingers or hands,symptoms that were associated with pain in over 20%of the cases.When comparing the scores in the two questionnaires,a statistically significant relationship(P<0.001)was found between the presence of neuropathic symptoms and a decreased quality of life.This correlation was consistent when the patients were stratified by sex,disease stage,comorbidities and the presence of stoma or treatment type,suggesting that neuropathy in itself may be a reason for a decreased quality of life.At the 3 year final assessment,median recurrence-free survival in stageⅢpatients was 26.88 mo.When stratified by completion of chemotherapy,median recurrence freesurvival of stageⅢpatients that completed chemotherapy was 28.27 mo vs 24.33 mo in patients that discontinued chemotherapy due to toxicity,a difference that did not reach statistical significance.CONCLUSION CIPN significantly impacts QoL in colorectal cancer patients.CIPN is also the most frequent reason for treatment discontinuation.Physicians should actively assess for CIPN in order to prevent chronic neuropathy. | Iulian Prutianu Teodora Alexa-Stratulat Elena Octaviana Cristea Andrei Nicolau Diana Cornelia Moisuc Alina Alexandra Covrig Karina Ivanov Adina Emilia Croitoru Monica Ionela Miron Mihaela Ioana Dinu Anca Viorica Ivanov Mihai Vasile Marinca Iulian Radu Bogdan Gafton | 2022 | World Journal of Clinical Cases2022,10,10: | 0 |