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| 1 | Surface pollen assemblages of human-disturbed vegetation and their relationship with vegetation and climate in Northeast China显示文摘Pollen assemblages of 53 surface pollen samples from farmlands and wastelands in Northeast China were analyzed. Tree pollen percentages were usually higher than 30%, with Pinus (26.9%), Quercus (0.9%), Betula (0.9%) and Populus (0.7%) as the major types, and herb pollen percentages were usually higher than 50%, with weedy Poaceae (8.7%), Chenopodiaceae (7.1%), Artemisia (1.9%) and Compositae (3.5%) as the major taxa. Thus, the pollen assemblages were consistent with the regional vegetation compositions. However, there were differences in pollen assemblages among regions, especially among different geomorphological units. For example, in the mountains, there were more types of tree pollen and higher total percentages (average 42%) than in other areas, while cereal pollen percentages were lowest (11.2%). In the hills and high plains, herbs made up more than 60% of the pollens, with cereals (average 53.6%) the dominant type. In the low plains, pollen types were similar to those in the hills and high plains, but total pollen concentrations and the proportion of Concentricystes were much higher, while cereal pollen percentages were slightly lower (average 41.6%). Pollen assemblages in different land use types also differed. For example, in farmland, cereal pollen percentages were more than 40% and Chenopodiaceae was usually less than 2.5%, while in wasteland, weedy Poaceae was usually less than 10% and Chenopodiaceae was usually higher than 25%. Total pollen concentrations in farmland (average 3909 grains/g) were much lower than in wasteland (average 15074 grains/g). Redundancy analysis revealed that pollen assemblages were significantly negatively correlated with mean annual temperature (-0.73) and July mean temperature (-0.81) and significantly positively correlated with mean annual precipitation (0.48), indicating that pollen assemblages in the artificial or human-disturbed vegetation reflect regional climate well. Comparison of pollen assemblages in different areas of northern China showed that pollen concentrations reflect the intensities of human impact to some degree. For example, pollen concentrations decrease as human impacts increase in intensity. The cereal pollen proportions in farmland differed by area. In Northeast China, cereal pollen proportions were distinctly higher than in most other areas of northern China, suggesting differences in planting habits and climate. | LI ManYue LI YueCong XU QingHai PANG RuiMing DING Wei ZHANG ShengRui HE ZhiGuo | 2012 | Chinese Science Bulletin2012，57，5： | 10 |
| 2 | Targeting fibrosis: mechanisms and clinical trials显示文摘Fibrosis is characterized by the excessive extracellular matrix deposition due to dysregulated wound and connective tissue repair response.Multiple organs can develop fibrosis,including the liver,kidney,heart,and lung.Fibrosis such as liver cirrhosis,idiopathic pulmonary fibrosis,and cystic fibrosis caused substantial disease burden.Persistent abnormal activation of myofibroblasts mediated by various signals,such as transforming growth factor,platelet-derived growth factor,and fibroblast growh factor,has been recongized as a major event in the occurrence and progression of fibrosis.Although the mechanisms driving organ-specific fibrosis have not been fully elucidated,drugs targeting these identified aberrant signals have achieved potent anti-fibrotic efficacy in clinical trials.In this review,we briefly introduce the aetiology and epidemiology of several fibrosis diseases,including liver fibrosis,kidney fibrosis,cardiac fibrosis,and pulmonary fibrosis.Then,we summarise the abnormal cells(epithelial cells,endothelial cells,immune cells,and fibroblasts)and their interactions in fibrosis.In addition,we also focus on the aberrant signaling pathways and therapeutic targets that regulate myofibroblast activation,extracellular matrix cross-linking,metabolism,and inflammation in fibrosis.Finally,we discuss the anti-fibrotic drugs based on their targets and clinical trials.This review provides reference for further research on fibrosis mechanism,drug development,and clinical trials. | Manyu Zhao Liqun Wang Mengzhu Wang Shijie Zhou Ying Lu Huijie Cui Alexandra C.Racanelli Ling Zhang Tinghong Ye Bisen Ding Ben Zhang Jinliang Yang Yuqin Yao | 2022 | Signal Transduction and Targeted Therapy2022，7，7： | 1 |
| 3 | Maternal genetic structure of a neolithic population of the Yangshao culture显示文摘The Yangshao culture is one of the most influential Neolithic cultures in East Asia.The populations associated with the Yangshao culture were widely distributed along the Yellow River basin and were suggested to play a profound role in the present-day East Asians.To date,the population of the Yangshao culture is largely investigated through archaeological studies. | Bo Miao Yichen Liu Wanfa Gu Qingli Wei Qian Wu Wenjun Wang Ming Zhang Manyu Ding Tianyi Wang Juncen Liu Feng Liu Peng Cao Qingyan Dai Ruowei Yang Xiaotian Feng Wanjing Ping Weihong Hou Haibing Yuan Qiaomei Fu | 2021 | Journal of Genetics and Genomics2021，48，8： | 0 |
| 4 | Study on Comprehensive Efficiency Evaluation of Rural Power Grid under Rural Revitalization Strategy Considering Regional Differences显示文摘As an essential infrastructure,the rural power grid is vital in promoting agricultural and rural carbon sequestration and improving rural energy electrification.It is necessary to carry out in-depth research on its comprehensive efficiency.Based on the requirements of“double carbon”and rural revitalization strategy for the rural Power Grid,this paper focuses on the modernization and low-carbon transformation of the rural Power Grid.It constructs an input-output index system for the investment efficiency of the rural Power Grid in China under the new situation.It uses the primary data of the rural Power Grid of 30 prefecture-level cities in China from 2019 to 2021 to evaluate the investment efficiency of the rural Power Grid in China through a three-stage DEA model.The empirical results show that:considering the regional differences,the comprehensive efficiency of the rural Power Grid in backward areas is significantly improved;that is,the three-stage DEA method can more objectively evaluate the comprehensive efficiency of the rural Power Grid.In the context of the continued promotion of the rural revitalization strategy,to improve the comprehensive efficiency of the rural Power Grid,it is necessary to improve the technical level of the rural Power Grid further and appropriately expand the scale of investment in the rural Power Grid. | Huiru Zhao Manyu Yao Zhenqi Bai Yue Zhang Zhihua Ding Zhenda Hu | 2023 | Energy Engineering2023，120，10： | 0 |
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