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3篇 您的检索式:作者名="Manuela Neumann"
    题名 作者 年代 出处 被引量
1TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia显示文摘Ian RA Mackenzie Rosa Rademakers Manuela Neumann 2010Lancet Neurology2010,,:1
2Interdisciplinary management of central nervous system metastasis and neoplastic meningitis:recent developments and future perspectives显示文摘The incidence of metastatic disease in the central nervous system(CNS)is rising.According to current estimates,up to a third of adult cancer patients will suffer from CNS metastasis.Clinical evidence-based data from prospective randomized trials are rare,however,because CNS metastasis patients were often excluded from clinical trial participation.The management of CNS metastasis patients is therefore rather ill-defined and an interdisciplinary challenge.Recent basic and translational science data have begun contributing to a more profound understanding of the molecular mechanisms leading to invasion of tumor cells into the CNS.This report reviews advances,challenges,and perspectives in this field.Ghazaleh Tabatabai Marilin Koch Cristiana Roggia Juliane Ebert Claus Garbe Friedegund Meier Sara Brucker Eva Maria Grischke Diethelm Wallwiener Robert Möhle Lothar Kanz Walter Erich Aulitzky Ulrike Ernemann Christian laFougere Konstantin Nikolaou Bernd Pichler Jens Schittenhelm Manuela Neumann Falko Fend Stefan Czemmel Sven Nahnsen Frank Paulsen Daniel Zips Maike van Lessen Hans-Otto Karnath Ulf Ziemann Constantin Roder Marco Skardelly Jürgen Bernd Honegger Marcos Tatagiba 2016Journal of Cancer Metastasis and Treatment2016,2,1:0
3利用激光显微切割/压力弹射技术和纳流液相色谱/质谱/质谱联用系统(LC/MS/MS)对死后人脑组织中的蛋白质进行鉴定显示文摘大多数神经退化性疾病,例如帕金森氏症、阿滋海默症等的在分子层面的发病机理目前尚不清楚.大多数蛋白质的表达分析都是在完整组织均质化制备的样品的基础上完成的.用这种方法制备的样品,没有提供特定细胞类型的相关改变的信息.本研究的目的在于检查用激光显微切割方法制备死后脑组织单细胞类型样品能否用于蛋白质表达分析.Christian Sauber Bernd Sgmüller Manuela Neumann Hans A.Kretschmar 2004药物分析杂志2004,24,6:0
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