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| 1 | One step synthesis of pyrido[1,2-a]benzimidazole derivatives of aryloxypyrazole and their antimicrobial evaluation显示文摘A new series of pyrido[1,2-α]benzimidazole derivatives bearing the aryloxypyrazole nucleus have been synthesized by base-catalyzed cyclocondensation reaction through multi-component reaction(MCR) approach.All the synthesized compounds were investigated against a representative panel of pathogenic strains using broth microdilution minimum inhibitory concentration(MIC) method for their in vitro antimicrobial activity.Reviewing the data,majority of the compounds were found to be active against employed pathogens.SAR study explores that antimicrobial activity is strongly depends on the nature of the substituents at the ether linked aryl ring attached to the pyrazole unit,together with the substituent present on the C_5 of the benzimidazole unit. | Hardik H.Jardosh Chetan B.Sangani Manish P.Patel Ranjan G.Patel | 2013 | Chinese Chemical Letters2013,24,2: | 9 |
| 2 | Microwave assisted synthesis of novel Hantzsch 1,4-dihydropyridines,acridine-1,8-diones and polyhydroquinolines bearing the tetrazolo[1,5-α]quinoline moiety and their antimicrobial activity assess显示文摘Microwave assisted efficient Hantzsch reaction via four-component coupling reactions of tetrazolo[1,5-α]quinoline-4-carbal-dehyde, dimedone/cyclohexane-1,3-dione,ethyl/methyl acetoacetate and ammonium acetate was described as the preparation of tetrazolo[1,5-α]quinoline based 1,4-dihydropyridines,acridine-1,8-diones and polyhydroquinolines.The process presented here is simple,rapid,environmentally welcoming and high yielding.All the derivatives were subjected to an in vitro antimicrobial screening against a representative panel of bacteria and fungi and results worth further investigations. | Niraj K.Ladani Divyesh C.Mungra Manish P.Patel Ranjan G.Patel | 2011 | Chinese Chemical Letters2011,22,12: | 7 |
| 3 | A new fast swelling poly[DAPB-co-DMAAm-co-AASS] superabsorbent hydrogel for removal of anionic dyes from water显示文摘The objective of this research is to utilize a new poly[N,N-diallyl pyrrolidinium bromide-co-N,Ndimethyl acrylamide-co-acrylic acid sodium salt]superabsorbent hydrogel(SAH)for the removal of two anionic dyes,e.g.,Reactive Red 5B(RR5B)and Reactive Orange M2R(ROM2R),from water.The SAH was characterized by swelling in water,FTIR,TGA and SEM.The SAH DDA6showed good swelling property and thermal stability.We have also investigated the parameters affecting dye adsorption such as pH,adsorbent dose,adsorption rate and initial dye concentration.The experimental data were also analyzed by applying the well known Langmuir and Freundlich isotherm models. | Yatin N.Patel Manish P.Patel | 2013 | Chinese Chemical Letters2013,24,11: | 5 |
| 4 | Synthesis of new superabsorbent poly(NIPAAm/AA/N-allylisatin)nanohydrogel for effective removal of As(Ⅴ) and Cd(Ⅱ) toxic metal ions显示文摘The present studies highlight the effective removal of As(V) and Cd(II) from aqueous solutions by superabsorbent poly(NlPAAm/AA/N-allylisatin) nanohydrogel.Batch removal studies were performed as a function of treatment time,initial metal ion concentration,pH,and adsorbent dose.TEM micrographs confirm the particle size distribution in the range between 5 nm and 10 nm.The simple and metal ions adsorbed nanohydrogels were characterized by FT-IR,TGA,and EDX analysis.Finally,the equilibrium removal efficiency of the nanohydrogel was analyzed according to the Langmuir and Freundlich adsorption isotherm models which showed the removal of As(V) and Cd(II) metal ions fitted to Freundlich and Langmuir isotherms,respectively.Removal efficiency order of the metal ions is As(V) > Cd(II). | Viran P.Mahida Manish P.Patel | 2014 | Chinese Chemical Letters2014,25,4: | 5 |
| 5 | Synthesis and in vitro antimicrobial screening of new pyrano[4,3-b]pyrane derivatives of 1H-pyrazole显示文摘pyrano 的一个新系列[4,3-b ] pyrane 4al 适用 1H-pyrazole 被一个壶底综合了 1H-pyrazole-4-carbaldehyde 1al 的催化 cyclocondensation 反应, malononitrile 2 并且 4-hydroxy-6-methylpyrone 3。所有综合混合物对六细菌的病原体被屏蔽,也就是 B。subtilis, C。tetani, S。pneumoniae, S。typhi, V。cholerae, E。coli 和抗真菌的活动对,二真菌的病原体,一。fumigatus 和 C。用肉汤 microdilution MIC 方法的 albicans。一些混合物被发现同等或更多的有势力比商业药的,对大多数采用的种类。 | Chetan B.Sangani Divyesh C.Mungra Manish P.Patel Ranjan G.Patel | 2012 | Chinese Chemical Letters2012,23,1: | 4 |
| 6 | Molecular iodine catalyzed synthesis of tetrazolo[1,5-a]-quinoline based imidazoles as a new class of antimicrobial and antituberculosis agents显示文摘一系列一些新 tetrazolo [1,5-a ] 喹啉基于的 tetrasubstituted 咪唑衍生物 6al 被 tetrazolo 的反应综合了[1,5-a ] quinoline-4-carbaldehyde 3ad, benzil 4,芳香的胺 5ac 和铵醋酸盐面对通过一个壶多部件反应(宏) 的碘来临。所有衍生物为值得进一步的调查的抗菌剂和 antituberculosis 活动和结果被屏蔽。 | Divyesh C.Mungra Harshad G.Kathrotiya Niraj K.Ladani Manish P.Patel Ranjan G.Patel | 2012 | Chinese Chemical Letters2012,23,12: | 3 |
| 7 | An efficient synthesis of 3'-quinolinyl substituted imidazole-5-one derivatives catalyzed by zeolite and their antimicrobial activity显示文摘新喹啉基于的一系列一些 imidazole-5-one 衍生物被 oxazol-5-ones,各种各样的代替 p 的苯胺和沸石的熔化在 pyridine 综合了。所有衍生物受到一在里面对值得进一步的调查的细菌和真菌和结果的一块代表性的面板屏蔽的 vitro 抗菌剂。 | Harshad G.Kathrotiya Nilav A.Patel Ranjan G.Patel Manish P.Patel | 2012 | Chinese Chemical Letters2012,23,3: | 3 |
| 8 | Synthesis and in vitro antimicrobial activity of N-arylquinoline derivatives bearing 2-morpholinoquinoline moiety显示文摘A new series of N-arylquinoline derivatives 5a-x bearing 2-morpholinoquinoline moiety has been synthesized by one pot base catalyzed cyclocondensation reaction of 2-morpholinoquinoline-3-carbaldehydes 2a-c,malononitrile 3 andβ-enaminones 4a-h. All the synthesized compounds were screened for their in vitro antimicrobial activity against six bacterial pathogens,namely Streptococcus pneumoniae,Clostridium tetani,Bacillus subtilis,Salmonella typhi,Vibrio cholerae,Escherichia coli and against two fungal pathogens,Aspergillus fumigatus and Candida albicans using broth microdilution MIC method.Of the compounds studied,majority of the compounds were found to active against C.tetani,B.subtilis and C.albicans as compared to first-line standard drugs. | Jigar A.Makawana Manish P.Patel Ranjan G.Patel | 2012 | Chinese Chemical Letters2012,23,4: | 2 |
| 9 | Synthesis of N-arylquinolone derivatives bearing 2-thiophenoxyquinolines and their antimicrobial evaluation显示文摘A new series of 2-thiophenoxyquinolines based trifluoromethyl substituted N-aryl quinolone derivatives8a–f and 9a–f have been synthesized via a one-pot multicomponent reaction. In vitro antimicrobial activity of the synthesized compounds was investigated against a representative panel of pathogenic strains. Compounds 8c, 9c and 9e exhibited comparable antimicrobial activity to first line drugs. | Mehul B.Kanani Manish P.Patel | 2014 | Chinese Chemical Letters2014,25,7: | 1 |
| 10 | Synthesis,characterization and antimicrobial activity of some new biquinoline derivatives containing a thiazole moiety显示文摘A series of new biquinoline derivatives containing a thiazole moiety were synthesized by a one-pot,base-catalyzed cyclocondensation reaction of 2-chloro-3-formyl quinoline,malononitrile and enaminone.All the synthesized compounds were characterized by elemental analysis,FT-IR,~1H NMR and ^(13)C NMR data.All the synthesized compounds were screened against three bacterial pathogens,namely Bacillus cereus,B.substilis and Escherichia coli and for antifungal activity against three fungal pathogens,Aspergillus niger,Fusarium oxisporum and Rhizopus using the disc diffusion method. | Nirav K.Shah Nimesh M.Shah Manish P.Patel Ranjan G.Patel | 2012 | Chinese Chemical Letters2012,23,4: | 1 |
| 11 | PS-TBD triggered general protocol for the synthesis of 4H-chromene,pyrano[4,3-b]pyran and pyrano[3,2-c]chromene derivatives of 1H-pyrazole and their biological activities显示文摘A general protocol has been developed for the facile construction of titled derivatives via three component reaction between 3-substituted phenyl-1H-pyrazole-4-carbaldehyde, malononitrile and various Michael donors in presence of 5 mol% polystyrene supported 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene(PS-TBD). PS-TBD was reused for at least five runs with nearly constant catalytic activity. All compounds were screened for antimicrobial and antioxidant activities. | Nileshkumar D.Vala Hardik H.Jardosh Manish P.Patel | 2016 | Chinese Chemical Letters2016,27,1: | 1 |
| 12 | Superabsorbent amphoteric nanohydrogels: Synthesis,characterization and dyes adsorption studies显示文摘The goal of the present research is to remove high percentage of cationic and anionic dyes such as,Neutral Red, Safranin O and Indigo Carmine from aqueous solutions by poly(NIPAAm/N,Ndiallylpyrrolidinium bromide/AA) superabsorbent amphoteric nanohydrogels synthesized using the inverse microemulsion polymerization method. Effect of various parameters such as, treatment time,initial dye concentration, p H and adsorbent dose were investigated. Furthermore, kinetics and isotherms adsorption models were applied to determine the maximum adsorption and mechanism for adsorption,which shows that adsorption obeyed the pseudo-second order kinetics. From the results, removal of dyes within the nanohydrogel was found to be in the order: AB-74 < BR-2 BR-5. | Viran P.Mahida Manish P.Patel | 2016 | Chinese Chemical Letters2016,27,3: | 0 |