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| 1 | 植物CBL基因家族的研究进展显示文摘细胞中游离的Ca2+是植物细胞中普遍存在的第二信使,类钙调神经素B亚基蛋白CBL作为一种特殊的钙感受器在植物生长发育和逆境胁迫响应过程中发挥重要作用。本文主要对植物CBL家族的起源与进化、蛋白结构、亚细胞定位以及CBL的功能进行综述,并对今后钙感受器CBL家族的研究重点和发展方向进行了展望。 | 董连红 史素娟 S M Nuruzzaman Manik 苏玉龙 刘朝科 冯祥国 胡晓明 王倩 刘好宝 | 2015 | 核农学报2015，29，5： | 15 |
| 2 | 2017欧洲心脏病学会/欧洲心胸外科协会心脏瓣膜病管理指南中经导管主动脉瓣置换术相关更新解读显示文摘自2012欧洲心脏协会/欧洲心胸外科协会关于心脏瓣膜病的管理指南发布以来,新的临床证据又大量积累。这些新证据使欧洲心脏协会/欧洲心胸外科协会需要更新瓣膜病的管理指南以达到心内科与心外科医师间的共识。该文将从经导管主动脉瓣置换术出发,解读2017年新指南所作出的更新。 | Tasalak Thonghong Manik Chopra Ole De Backer Lars Sndergaard 王玺 | 2018 | 华西医学2018，33，2： | 12 |
| 3 | Effect of different pre-sowing treatments on seed germination percentage and growth performance of Acacia auriculiformis显示文摘Seed morphology,germination and seedlings growth of Acacia auriculiformis were studied.The experiment was conducted in the nursery of Forestry and Wood Technology Discipline,Khulna University,Bangladesh.Matured seeds of the species were collected from healthy trees of road side plantation from different areas of Khulna District,Bangladesh and treated with five pre-sowing treatments(control,immersion in cold water,immersion in hot water,scarification with sand paper and immersion in concentrated H2SO4).The average length,breadth and thickness were found to be(0.58±0.017) cm,(0.44±0.007) cm and(0.20±0.089) cm,respectively.Germination was conducted in polybags with a mixture of top soil,coconut husk,coarse sand,and fine sand in a ratio of 3:4:1:1.Results reveal that pre-sowing treatments influences the germination rates of seeds that significantly increase the percentage germination compared with those in control(43%) and cold water treatment(52%).The highest germination success rate was found 83% in hot water treatment followed by 78% in scarification with sand paper,and 75% with immersion in H2SO4.Germination started from 7 to 12 days and completed between 28 and 35 days period in all treatments.ANOVA showed the significant difference(p<0.05) among the treatments in seed germination,but no significant difference among treatment with regard to starting day,closing day and total germination period.In case of height and diameter growth,seedlings originated from the seeds with hot water treatment shows significantly higher in wet season(from May to July).Hot water treatment can be recommended on seed germination of the species in rural Bangladesh. | Md.Salim Azad Mizanur Rahman Manik Md.Shamin Hasan Md.Abdul Matin | 2011 | Journal of Forestry Research2011，22，2： | 10 |
| 4 | Node Coverage Algorithms in Wireless Sensor Networks Using Mobile Agents显示文摘This paper proposes fault tolerant algorithms for routing mobile agents in a single channel wireless sensor network which cover every node in the network. These algorithms use local knowledge (assume no knowledge of global deployment or topology, etc). We propose the algorithms and show mathematical analysis to support our claims. The paper ends with simulation studies and discussion of results. | RAINA Manik KUMAR Subhas PATRO Ranjeet | 2006 | 自动化学报2006，32，6： | 9 |
| 5 | Mineralogy and carbothermal reduction behaviour of vanadium-bearing titaniferous magnetite ore in Eastern India显示文摘Vanadium-bearing titaniferous magnetite bands hosted by Precambrian gabbro-norite-anorthositic rocks or their metamorphic equivalents were discovered in some parts of Eastern Indian Shield,containing 48%-49%Fe(total),10%-25%TiO2,and 0.3%-2.20%V2O5by mass.Mineralogical and petrological study,composition,and characterization of the vanadium-bearing titaniferous magnetite ore were carried out by scanning electron microscopy-energy dispersive X-ray(SEM-EDX),wave length X-ray florescence(WDXRF),inductively coupled plasma-atomic emission spectroscopy(ICP-AES),X-ray difraction(XRD),etc.Chemical beneficiation for valuable metals,such as Fe,Ti,and V,was performed by reduction roasting.The direct and indirect reduction were investigated by mixing the lump ore with solid activated charcoal in a closed reactor and purging the reducing gas mixture in standard reducibility index apparatus at diferent temperatures and time intervals.The reduction roasting parameters were optimized.Finally,the reduced samples were crushed and upgraded by magnetic separation.The results show that,the maximum mass fractions of magnetic and nonmagnetic parts achieved are 69.36%and 30.64%,respectively,which contain 10.6%TiO2and 0.84%V2O5in the magnetic part and 36.5%TiO2and 0.22%V2O5in the nonmagnetic part. | Saikat Samanta Manik Chandra Goswami Tapan Kumar Baidya Siddhartha Mukherjee Rajib Dey | 2013 | International Journal of Minerals,Metallurgy and Materials2013，20，10： | 9 |
| 6 | One-step synthesis of N-doped metal/biochar composite using NH_3-ambiance pyrolysis for efficient degradation and mineralization of Methylene Blue显示文摘A series of new biochar-supported composite based on the combination of biochar and metallic nanoparticles(NPs)were produced through single-step pyrolysis of FeCl_3–Ti(OBu)_4 laden agar biomass under NH_3 environment.The physiochemical properties of composites were characterized thoroughly.It has found that heating temperature and N-doping through NH_3-ambiance pyrolysis significantly influence the visible-light sensitivity and bandgap energy of composites.The catalytic activities of composites were measured by degradation of Methylene Blue(MB)in the presence or absence of H_2O_2 and visible-light irradiation.Our best catalyst(N–TiO_2–Fe_3O_4-biochar)exhibits rapid and high MB removal competency(99.99%)via synergism of adsorption,photodegradation,and Fenton-like reaction.Continuous production of O_2U^-and UOH radicles performs MB degradation and mineralization,confirmed by scavenging experiments and degradation product analysis.The local trap state Ti^(3+),Fe_3O_4,and N-carbon of the catalyst acted as active sites.It has suggested that the Ti^(3+)and N-doped dense carbon layer improve charge separation and shuttle that prolonged photo-Fenton like reaction.Moreover,the catalyst is highly stable,collectible,and recyclable up to 5 cycles with high MB degradation efficiency.This work provides a new insight into the synthesis of highly visible-light sensitized biocharsupported photocatalyst through NH_3-ambiance pyrolysis of NPs-laden biomass. | Md Manik Mian Guijian Liu Balal Yousaf Biao Fu Rafay Ahmed Qumber Abbas Mehr Ahmed Mujtaba Munir Liu Ruijia | 2019 | Journal of Environmental Sciences2019，31，4： | 8 |
| 7 | 降解烤烟秸秆和烟碱菌株的筛选及其产酶特性显示文摘【目的】为获得能够降解烤烟秸秆和烟碱的菌株,并探索其降解烤烟秸秆的利用途径。【方法】以烤烟秸秆为唯一碳氮源,从烟田土壤中进行了菌株的筛选。采用形态学观察、生理生化特性鉴定、16S rRNA基因序列鉴定等方法对该菌株进行了鉴定,并对其以烤烟秸秆为底物进行液态发酵的产酶活性和木质纤维素降解效果进行了测定。【结果】结果表明:该菌株为巨大芽孢杆菌(Bacillus megaterium)。在以烤烟秸秆为主要营养物质液态发酵条件下该菌株具有较强的木质素降解能力,最大漆酶活力达到418.52 U/L,而木质素过氧化物酶和锰过氧化物酶的最大酶活分别为19.71 U/L和64.71 U/L。此外,发酵20 d后该菌能够完全降解发酵液中的烟碱。【结论】本研究筛选到了1株能够较好降解烤烟秸秆和完全降解烟碱的巨大芽孢杆菌(Bacillus megaterium),且该菌株具有利用烤烟秸秆生产漆酶的应用价值。 | 苏玉龙 王倩 张成省 顾金刚 史素娟 SM Nuruzzaman Manik 毛静静 李世贵 雷强 伍仁军 殷英 屈健康 李亮 刘好宝 | 2015 | 微生物学报2015，55，12： | 8 |
| 8 | 林烟草蛋白激酶NsylCIPK3基因的克隆与功能分析显示文摘CIPK蛋白激酶家族(CBL-interacting protein kinase)是一类丝氨酸/苏氨酸蛋白激酶家族,与类钙调磷酸酶B亚基CBL(calcineurin B-like protein)蛋白共同形成CBL-CIPK网络,在植物的生长发育和逆境胁迫响应过程中发挥重要作用。烟草中该家族的研究还比较少,本研究从林烟草(Nicotiana sylvestris)中获得一个CIPK家族基因,该基因与拟南芥和杨树中的CIPK3同源性分别为68.4%和87.5%,将其命名为Nsyl CIPK3。氨基酸序列分析表明,Nsyl CIPK3具有CIPK蛋白家族的典型结构特征,在N端和C端分别具有典型的激活环结构域和NAF结构域。进化树分析显示,Nsyl CIPK3属于CIPK蛋白亚家族Ⅱ。表达模式研究表明,该基因在林烟草的叶和腋芽中的表达量相对较高,在主根中的表达量次之,在侧根、茎、花瓣和萼片中的表达量相对较低,并且在烟草成熟期的叶中表达量明显升高。在高盐、紫外光和低钾胁迫下该基因的表达发生不同程度的上调。酵母双杂交结果显示,Nsyl CIPK3可与Nsyl CBL9互作。推测Nsyl CIPK3可能通过与Nsyl CBL9互作形成信号通路,激活下游靶蛋白,参与烟草响应非生物逆境胁迫的信号转导过程。 | 董连红 史素娟 S M Nuruzzaman Manik 苏玉龙 毛静静 王傚弘 周开燕 刘林 王倩 刘好宝 | 2015 | 植物遗传资源学报2015，16，3： | 4 |
| 9 | Interleukin-28 and hepatitis C virus genotype-4:Treatment-induced clearance and liver fibrosis显示文摘AIM:To investigate the association between interleukin-28B(IL28B) genotype and response to treatment and hepatic fibrosis in patients with hepatitis C virus(HCV) genotype 4.METHODS:Two hundred and one HCV-genotype 4 patients were included.All patients were treated with Peginterferon alph2a/Ribavirin for 48 wk.End of treatment response(ETR) was defined as loss of detectable serum HCV RNA at the end of treatment.Sustained viral response(SVR) was defined as loss of detectable serum HCV RNA at the end of 24 wk follow up.Genotyping of IL28B rs12979860 was performed using the TaqMan assay.We used logistic regression to estimate the adjusted odds ratio(aOR) and 95%CI.RESULTS:The study included 201 HCV-genotype 4 patients.The majority of patients were men(89.6%),with a median age of 47 years,inter-quartile range(40-51).Approximately 62.5% of patients had ETR,and 49.6% had SVR.Individuals who achieved SVR were more likely to be younger(χ 2 = 4.91,P = 0.027),and less likely to have fibrosis(χ 2 = 15.54,P < 0.0001),or inflammation(χ 2 = 7.58,P = 0.006).The genotype distribution of rs12979860 was 36.2%,49.0% and 14.8% for genotypes CC,CT,and TT,respectively.In these participants,rs12979860 genotype distribution did not differ by gender(P = 0.466),pretreatment viral load(P = 0.600),inflammation(P = 0.435),or fibrosis(P = 0.291).The frequencies of IL28B rs12979860 genotypes were TT(14.8%),CT(49.0%),and CC(36.2%).Compared to rs12979860 genotype TT,aORs(95%CI) for ETR and SVR were:CC genotype,[17.55(5.34-57.69) and 5.92(2.09-16.76),respectively];CT genotype,[5.15(1.80-14.78) and 2.48(0.94-6.52),respectively].In the current study,the patients who did not achieve ETR or SVR had a lower prevalence of rs12979860 CC(17.4% and 23.3%,respectively) than individuals who had ETR or SVR(47.9% and 47.2%,respectively).Individuals with rs12979860 CC genotype had approximately 6 times the odds of SVR compared to individuals with TT genotype(aOR = 5.92;95%CI:2.09-16.76).Similarly,patients with CT genotype had SVR more often than patients with TT genotype(aOR = 2.48;95%CI:0.94-6.52).Carrying at least one copy of the C allele(genotypes CT and CC) had almost 8 times the probability of ETR compared to those with genotype rs12979860 TT(aOR = 7.87;95%CI:2.84-21.82),and approximately 3 times the odds of SVR compared to those with genotype rs12979860 TT(aOR = 3.46;95%CI:1.37-8.74).In addition,data were consistent with a significant gene-dose relationship(aOR = 4.05/allele;95%CI:2.27-7.22).The association between rs12979860 genotype and SVR was similar among those who achieved and those who did not achieve SVR.CONCLUSION:In HCV-genotype 4 patients,rs12979860 is a sensitive predictor of viral clearance,independent of viral load,age,gender or fibrosis,with no similar relation to severity of fibrosis. | Moutaz Derbala Nasser Rizk Fatima Shebl Saad Alkaabi Nazeeh Eldweik Anil John Manik Sharma Rafie Yaqoob Muneera Almohanadi Mohammed Butt Khaled Alejji | 2012 | World Journal of Gastroenterology2012，18，47： | 2 |
| 10 | Candidal pituitary abscess: case report显示文摘 | Heary RF Maniker AH Wolansky LJ | 1995 | Neurosurgery1995，36，5： | 1 |
| 11 | Computation with the help of a digital computer of magnetic anomalies caused by bodies of arbitrary shape 显示文摘 | Manik Talwani | 1965 | Geo- physics1965，30，5： | 1 |
| 12 | Candidal pituitary abscess case report 显示文摘 | Heary RF Maniker AH Wolansky LJ | 1995 | Neurosurgery1995，36，10： | 1 |
| 13 | Antimicrobial resistance in Enterobacteriaceae in Brooklyn,NY:epidemiology and relation to antibiotic usage patterns显示文摘 | Saurina G Quale JM Manikal VM | 2000 | J Antimicrob Agents Chemother2000，45，： | 1 |
| 14 | Vitrification of buffalo (bubalus bubalis) oocytes显示文摘 | Dhali A Manik R S Das S K | 2000 | Theriogenology2000，，： | 1 |
| 15 | Malignant peripheral nerve sheath tumors 显示文摘 | Gupta G Maniker A | 2007 | Neurosurg Focus2007，22，： | 1 |
| 16 | Erythropoietin as a neuroprotective agent in traumatic brain injury Review 显示文摘 | Mammis A Mclntosh TK Maniker All | 2009 | Surg Neurol2009，71，5： | 1 |
| 17 | Endemic carbapenem resistant acinetobacter species in brooklyn,New York:citywidep revalence,interinstitutional spread,and relation to antibiotic usage显示文摘 | MANIKAL V M LANDMAN D SAUINAG | 2000 | Clin Infect Dis2000，31，1： | 1 |
| 18 | Comparative efficacy of secukinumab against adalimumab and infliximab in patients with moderate-to-severe plaque psoriasis显示文摘Background: Psoriasis is a common, chronic, immune-mediated inflammatory skin disease with increased epidermal proliferation. The objective of this review was to systematically identify the evidence and perform a network meta-analysis (NMA) to estimate the relative efficacy of secukinumab (SEC) against adalimumab (ADA) and infliximab (INF) for the treatment of moderate-to-severe plaque psoriasis.Methods: A systematic literature review (SLR) was conducted according to a pre-specified protocol to identify relevant studies. Initially, the databases were searched from database inception till June 2013, and the SLR was updated in April 2020. The eligibility criteria included adult patients (≥18 years old) with moderate-to-severe plaque psoriasis, and the SLR included randomized controlled trials (RCTs). The comparators of interest were SEC, ADA, INF, and placebo (PLA), while outcomes of interest were Psoriasis Area and Severity Index (PASI) (50, 75, and 90) at weeks 12, 16, and 24. A Bayesian NMA for PASI was utilized with a framework that evaluated the probability of PASI responses in different categories of PASI thresholds within a single model.Results: A total of 23 RCTs that assessed the efficacy of SEC, ADA, and INF in patients with moderate-to-severe plaque psoriasis were identified. At 12 weeks, SEC was associated with a significantly better response compared with PLA and ADA for PASI 75 and 90, while response results were comparable against INF. At 12 weeks, risk ratio (95% confidence interval) derived from NMA for SECvs. ADA and INF for PASI 75 was 1.35 (1.19, 1.57) and 1.01 (0.90, 1.18), respectively. At the 16-week and 24-week time interval, SEC was significantly better than PLA, ADA, and INF for PASI 75 and 90.Conclusion: Efficacy of SEC in the treatment of patient populations with moderate-to-severe plaque psoriasis is well demonstrated through NMA. | Ran Pan Xiaolun Wang Min Shu Jaydeep Das Manik Kalra Zhidong Wang | 2022 | Chinese Medical Journal2022，，1： | 1 |
| 19 | Malignant peripheral nerve sheath tumors显示文摘 | GUPTA G MAMMIS A MANIKER A | 2008 | Neurosurg Clin N Am2008，19，： | 1 |
| 20 | Microemulsion and Conventional Emulsion Copolymerizations of Styrene and n-Butyl Methacrylate,and Characterization of the Copolymers显示文摘 | REDDY G V JOSEPH V S MANIK C | 2000 | J Appl Polym Sci2000，77，2： | 1 |
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