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| 1 | Thermally reconfigurable quantum photonic circuits at telecom wavelength by femtosecond laser micromachining显示文摘The importance of integrated quantum photonics in the telecom band is based on the possibility of interfacing with the optical network infrastructure that was developed for classical communications.In this framework,femtosecond laser-written integrated photonic circuits,which have already been assessed for use in quantum information experiments in the 800-nm wavelength range,have great potential.In fact,these circuits,being written in glass,can be perfectly mode-matched at telecom wavelength to the in/out coupling fibers,which is a key requirement for a low-loss processing node in future quantum optical networks.In addition,for several applications,quantum photonic devices must be dynamically reconfigurable.Here,we experimentally demonstrate the high performance of femtosecond laser-written photonic circuits for use in quantum experiments in the telecom band,and we demonstrate the use of thermal shifters,which were also fabricated using the same femtosecond laser,to accurately tune such circuits.State-of-the-art manipulation of single-and two-photon states is demonstrated,with fringe visibilities greater than 95%.The results of this work open the way to the realization of reconfigurable quantum photonic circuits based on this technological platform. | Fulvio Flamini Lorenzo Magrini Adil S Rab Nicolo Spagnolo Vincenzo D’Ambrosio Paolo Mataloni Fabio Sciarrino Tommaso Zandrini Andrea Crespi Roberta Ramponi Roberto Osellame | 2015 | Light(Science & Applications)2015，4，1： | 5 |
| 2 | Co-encapsulation of curcumin and doxorubicin in albumin nanoparticles blocks the adaptive treatment tolerance of cancer cells显示文摘The adaptive treatment tolerance (ATT) of cancer cells is the main encumbrance to cancer chemotherapy. A potential solution to this problem is to treat cancer cells with multiple drugs using nanoparticles (NPs). In this study, we tested the co-administration of curcumin (Cur) and doxorubicin (Dox) to MCF-7 resistant breast cancer cells to block the ATTand elicit efficient cell killing. Drugs were co-administered to cells both sequentially and simultaneously. Sequential drug co-administration was carried out by pre-treating the cells with albumin nanoparticles (ANPs) loaded w让h Cur (Cur@ANPs) followed by treatment with Dox-loaded ANPs (Dox@ANPs). Simultaneous drug co-administration was carried out by treating the cells with ANPs loaded with both the drugs (Cur/Dox@ANPs). We found that the simultaneous drug co-administration led to a greater intra-cellular accumulation of Dox and cell killing with respect to the sequential drug co-administration. However;the simultaneous drug co-administration led to a lower intracellular accumulation of Cur with respect to the sequential drug co-administration. We showed that this result was due to the aggregation and entrapment of Cur in the lysosomes as soon as it was released from Cur@ANPs, a phenomenon called lysosomotropism. In contrast, the simultaneous release of Dox and Cur from Cur/Dox@ANPs into the lysosomes led to lysosomal pH elevation, which, in turn, avoided Cur aggregation, led to lysosome swelling and drug release in the cytosol, and finally provoked efficient cell killing. Our study shed the light on the molecular processes driving the therapeutic effects of anti-cancer drugs co-administered to cancer cells in different manners. | Seyed Mohammad Motevalli Ahmed Shaker Eltahan Lu Liu Andrea Magrini Nicola Rosato Weisheng Guo Massimo Bottini Xing-Jie Liang | 2019 | Biophysics Reports2019，5，1： | 3 |
| 3 | Clinical,histological,and virological features of hepatitis C virus carriers with persistently normal or abnormal alanine transaminase levels显示文摘 | Puoti C Magrini A Stati T | 1997 | Hepatology1997，26，6： | 1 |
| 4 | In-hospital percentage BNP reduction is highly predictive for adveme events in patients admitted for acute heart failure: the Italian RED study显示文摘 | Di Somma S Magrini L Pittoni V | 2010 | Cfit Care2010，14，3： | 1 |
| 5 | Additive value to clinical judgement of blood neutrophil gelatinase-associated lipocalin in diagnosis of acute kidney injury and prediction of mortality in patients hospitalized from the emergency department显示文摘 | Di Somma S Magrini L De Berardinis B | 2012 | Critical Care2012，16，1： | 1 |
| 6 | EGFR,HER2,and phospho-Akt are not predictive factors for response to first-line chemotherapy in patients with advanced non-small cell lung cancer (NSCLC)显示文摘 | Toschi L Metro G Magrini E | 2006 | J Clin Oncol2006，24，18： | 1 |
| 7 | On the application of a mem brahe air-liquid contactor for air dehumidification显示文摘 | lsetti C Nannei E Magrini A | 1997 | Energy and Buildings1997，25，3： | 1 |
| 8 | Akt phosphorylation and gefitinib efficacy in patients with advanced non-small-cell lung cancer显示文摘 | Cappuzzo F Magrini E Ceresoli G L | | 0，，5： | 1 |
| 9 | Maligant granular cell tumor of lateral femoral cutaneous nerve:report of a case with cytogenetic analysis显示文摘 | Di Tommasol L Magrini E Consales A | 2002 | Hum Pathol2002，33，12： | 1 |
| 10 | Cytogenetic analysis of oral malignant Melanoma显示文摘 | Farnedi A Magrini E Betts C M | 2005 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod2005，99，6： | 1 |
| 11 | Malignant granular cell tumor of the lateral femoral cutaneous nerve: Report of a case with cytogenetic analysis 显示文摘 | Di Tommaso L Magrini E Consales A | 2002 | Hum Pathol2002，33，12： | 1 |
| 12 | Method to improve corrosion resistance of AA 5083 by cerium based conversion coating and anodic polarization in molybdate solution显示文摘 | BRUNELLI K MAGRINI M DABALA M | 2012 | Corrosion Engi- neering Science and Technology2012，47，3： | 1 |
| 13 | Eco-industrial park de velopment in riode janeiro, braziha tool for sustainable de velopment显示文摘 | ELABRAS L B V MAGRINI A | 2009 | Journal of Cleaner Production2009，17，7： | 1 |
| 14 | A Proposal of Indicators for Sustainable Development in the Management of River Basins显示文摘 | Lucy T. Guimar?es Alessandra Magrini | 2008 | Water Resources Management2008，，9： | 1 |
| 15 | In-hospital brain natriuretic peptide and N-terminal prohormone brain natriuretic peptide variations are predictors of short-term and long-term outcome in acute decompensated heart failure显示文摘 | Di Somma S Magrini L Ferri E | 2011 | Crit Care2011，15，1： | 1 |
| 16 | Reducing cancer risks by improving organic carbon removal显示文摘 | Magrini B K | 1996 | J Am Water Works Assoc1996，8，6： | 1 |
| 17 | Endonasal endoscopic resection of an os odontoideum to decompress the eervicomedullary junction: a minimal access surgical technique 显示文摘 | Magrini S Pasquini E Mazzatenta D | 2009 | Spine2009，34，4： | 1 |
| 18 | Malignant granular cell tumor of the lateral femoral cutaneous nerve:report of a case with cytogenetic analysis显示文摘 | Di Tommaso L Magrini E Consales A | 2002 | Hum Pathol2002，33，12： | 1 |
| 19 | Usefulness of serial assessment of natriuretic peptides in the emergency department for patients with acute decompensated heart failure 显示文摘 | Disomma S Magrini L Piltoni V | 2008 | Congest Heart Faih2008，14，： | 1 |
| 20 | Malignant granular cell tumor of the lateral femoralcutaneous nerve : Report of a case with cytogeneticanalysis显示文摘 | Di Tommaso L Magrini E Consales A | 2002 | Hum Pathol2002，33，12： | 1 |
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