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	题名	作者	年代	出处	被引量
1	Kallikrein-related peptidases 6 and 10 are elevated in cerebrospinal fluid of patients with Alzheimer’s disease and associated with CSF-TAU and FDG-PET显示文摘Background:Alterations in the expression of human kallikrein-related peptidases(KLKs)have been described in patients with Alzheimer’s disease(AD).We elucidated the suitability of KLK6,KLK8 and KLK10 to distinguish AD from NC and explored associations with established AD biomarkers.Methods:KLK levels in cerebrospinal fluid(CSF),as determined by ELISA,were compared between 32 AD patients stratified to A/T/(N)system with evidence for amyloid pathology and of 23 normal controls with normal AD biomarkers.Associations between KLK levels and clinical severity,CSF and positron emission tomography(PET)based AD biomarkers were tested for.Results:Levels of KLK6 and KLK10 were significantly increased in AD.KLK6 differed significantly between AD A+/T+/N+and AD A+/T−/N+or NC with an AUC of 0.922.CSF pTau and tTau levels were significantly associated with KLK6 in AD.Conclusions:KLK6 deserves further investigations as a potential biomarker of Tau pathology in AD.	Oliver Goldhardt Inanna Warnhoff Igor Yakushev Ilijana Begcevic Hans Förstl Viktor Magdolen Antoninus Soosaipillai Eleftherios Diamandis Panagiotis Alexopoulos Timo Grimmer	2019	Translational Neurodegeneration2019，8，1：	3
2	Structures and speci-ficity of the human kallikrein-related peptidases KLK 4, 5, 6, and 7 显示文摘	Debela M Beaufort N Magdolen V	2008	Biol Chem2008，389，6：	1
3	Multifunctional potential of the plasminogen activation system in tumor invasion and metastasis (review)显示文摘	Reuning U Magdolen V Wilhelm O	1998	Int J Oncol1998，13，：	1
4	Impact of expression of the u PA system in sarcomas显示文摘	Taubert H Magdolen V Kotzsch M	2013	Biomark Med2013，7，3：	1
5	Multifunctional potential of the plasminogen activation system in tumor invasion and metastasis显示文摘	Reuning U Magdolen V Wilhelm O	1998	Int J Oncol1998，13，5：	1
6	Combined mRNA expression levels of members of the urokinase plasminogen activator( uPA) system correlate with disease-associated survival of soft-tissue sarcoma patients显示文摘	Kotzsch M Magdolen V Greither T	2011	BMC Cancer2011，11，：	1
7	Interference with the urokinase plasminogen activator system: a promising therapy concept for solid tumours显示文摘	Muehhnweg B Sperl S Magdolen V	2001	Expert Opin Biol Ther2001，1，4：	1
8	Development of semi-active road-friendly truck suspensions 显示文摘	Valasck M Kortiim W Sika Z Magdolen L Vaculfn O	1998	Control Engineering (S0967-0661)1998，6，6：	1
9	Combined mRNA expression levels of members of the urokinase plasminogen activator (uPA) system correlate with disease-associated survival of soft-tissue sarcoma patients显示文摘	Kotzsch M Magdolen V Greither T	2011	BMC Cancer2011，11，：	1
10	Inhibition of the tumor-associated urokinase-type plasminogen activator system:effects of high-level synthesis of soluble urokinase receptor in ovarian and breast cancer cells in vitro and vivo显示文摘	Magdolen V Kruger A Sato S	2003	Recent-Results-Cancer-Res2003，462，：	1
11	Molecular and functional interdependence of the urokinase-type plasminogen activator system with integrins 显示文摘	Reuning U Magdolen V Hapke S	2003	Biol Chem2003，384，8：	1
12	Circulating biomarker tissue kallikrein-related peptidase KLK5 impacts ovarian cancer patients' survival 显示文摘	Dora J Magdolen V Gkazepis A	2011	Ann Oncol2011，22，8：	1
13	Mutifunctional potential of the plasminogen activation system in tumor invasion and metastasis 显示文摘	Reuning U Magdolen V Wilhelm O	1998	Int J Oncol1998，13，：	1
14	Gene expression analysis of HUVEC in response to TF-binding 显示文摘	GROSSER M MAGDOLEN V BARETTON G	2011	Thromb Res2011，127，3：	1
15	Kallikrein-Related Peptidase 4显示文摘	Valérie Gratio Nathalie Beaufort Lina Seiz Josefine Maier G. Duke Virca Mekdes Debela Nicolai Grebenchtchikov Viktor Magdolen Dalila Darmoul	2010	The American Journal of Pathology2010，，3：	1
16	Development of semi- active road- friendly trucksuspensions显示文摘	Valasek M Kortum W Sika Z Magdolen L Vaculin O	1998	Control Engineering (S0967- 0661)1998，6，6：	1
17	显示文摘	Helfrich W Haisma HJ Magdolen V	2000	J Immunol Methods2000，237，12：	1
18	Combined mRNA expres- sion levels of members of the urokinase plasminogen activator (uPA) system correlate with disease - associated survival of soft - tissue sarcoma patients 显示文摘	Kotzsch M Magdolen V Greither T	2011	BMC Cancer2011，11，1：	1
19	Multifunctional potential of the plasminogen activation system in tumor invasion and metastasis(review) 显示文摘	Reuning U Magdolen V Wilhelm O	1998	Int J Oncol1998，13，5：	1
20	Retinotic acid upregulates the plasminogen activator system in human epidermal keratinocytes 显示文摘	Braungart E Magdolen V Degitz K	2001	J Invest Dermatol2001，116，5：	1

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