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| 1 | 视神经脊髓炎IgG刺激原代培养大鼠星形胶质细胞免疫反应显示文摘视神经脊髓炎(NMO)主要累及星形胶质细胞,导致中枢神经系统炎症、脱髓鞘和组织损伤。脑内病灶常高表达水通道蛋白4(AQP4),AQP4被认为是NMO血清IgG的抗原目标。根据NMO的可逆性及对NMO病灶演变特点的分析,笔者推测NMO IgG可能诱导了星形胶质细胞的动态免疫过程。培养原代大鼠星形胶质细胞,加入从NMO患者血清中提取或纯化的IgG,星形胶质细胞出现炎性增殖,同时基因表达出现与之匹配的明显变化。且星形胶质细胞反应因子脂质运载蛋白-2、多种趋化因子、细胞因子、应激反应因子的表达均增加。而在培养的原代星形胶质细胞中加入从正常对照者血清中提取的IgG则无上述变化。此星形胶质细胞的反应还与疾病种类相关。从复发缓解型多发硬化、Sj觟gren's或系统性红斑狼疮患者血清中提取的IgG加入培养的原代星形胶质细胞中也不能导致上述变化。笔者推测是NMO IgG与AQP4结合,导致星形胶质细胞出现炎症反应,并出现基因在转录和翻译水平的相应变化。抑制星形胶质细胞的炎症反应可能有助于减少星形胶质细胞增殖,缓解NMO病灶的发展。 | Howe CL Kaptzan T Magaa SM Ayers-Ringler JR LaFrance-Corey RG Lucchinetti CF | 2014 | 神经损伤与功能重建2014，9，3： | 4 |
| 2 | Caerulin-induced pancreatitis in rats: Histological and genetic expression changes from acute phase to recuperation显示文摘瞄准:为了学习组织学、联系胰腺炎的蛋白质 mRNA 累积,在老鼠从导致 caerulin 的胰腺炎的尖锐阶段胰改变到恢复。方法:尖锐胰腺炎被 caerulein 在男 Wistar 老鼠导致并且列在后面在上面为 90 d 由组织学并且胰的 mRNA 分析。胰在 0 点被把, 9, 24 h 并且 3, 5, 15, 30, 60, 90 d 正式就职以后。浮肿(E) , polymorphonuclear neutrophil (PMN ) 渗入,细胞质的空泡形成(V) ,酶原小粒弄空(ZD ) 和腺泡组织的破坏(广告) 是评估的用显微镜。联系胰腺炎的蛋白质(奶头) 和 L13A mRNAs 的累积被即时 PCR 确定。结果:主要组织学的变化出现在为 PMN 渗入和细胞质的 V 正式就职以后的 9 h 在为 E 和 ZD 的 24 h 和 3 d 分别地。所有参数在 5 d 以后被恢复,除了推迟了超过 30 d 的 ZD。主要广告在 15 d 以后被观察,值在 30 d 以后回到了正常。同样到组织学的变化, PAP mRNA 的累积在 24 h 与最高的累积在 9 h 被增加,差别消失在 5 d 以后。结论:从尖锐阶段发生到胰的胰腺炎,新生和重新区别的恢复并且奶头表示是只胰腺炎的尖锐回答。 | Javier Magaa-Gómez Guillermo López-Cervantes Ana María Calderón de la Barca | 2006 | World Journal of Gastroenterology2006，12，25： | 2 |
| 3 | Digital spiral object identification using random light显示文摘Photons that are entangled or correlated in orbital angular momentum have been extensively used for remote sensing,object identification and imaging.It has recently been demonstrated that intensity fluctuations give rise to the formation of correlations in the orbital angular momentum components and angular positions of random light.Here we demonstrate that the spatial signatures and phase information of an object with rotational symmetries can be identified using classical orbital angular momentum correlations in random light.The Fourier components imprinted in the digital spiral spectrum of the object,as measured through intensity correlations,unveil its spatial and phase information.Sharing similarities with conventional compressive sensing protocols that exploit sparsity to reduce the number of measurements required to reconstruct a signal,our technique allows sensing of an object with fewer measurements than other schemes that use pixel-by-pixel imaging.One remarkable advantage of our technique is that it does not require the preparation of fragile quantum states of light and operates at both low-and high-light levels.In addition,our technique is robust against environmental noise,a fundamental feature of any realistic scheme for remote sensing. | Zhe Yang Omar S Magaña-Loaiza Mohammad Mirhosseini Yiyu Zhou Boshen Gao Lu Gao Seyed Mohammad Hashemi Rafsanjani Gui-Lu Long Robert W Boyd | 2017 | Light(Science & Applications)2017，6，1： | 2 |
| 4 | Proliferating cell nuclear antigen (PCNA):a dancer With many partners 显示文摘 | Maga G Hubher U | 2003 | J Cell Sei2003，116，5： | 1 |
| 5 | Evidence based assessment of long-term results of plaque incision and vein grafting for Peyronie's disease显示文摘 | Montorsi F Salonia A Maga T | 2000 | J Urol2000，163，6： | 1 |
| 6 | Production and processing of milk from transgenic goats expressing human lysozyme in the mammary gland 显示文摘 | MAGA E A SHOEMAKER C F ROWE J D | 2006 | Journal of Dairy Science2006，89，2： | 1 |
| 7 | Furans in foods 显示文摘 | Maga JA | 1979 | Critieal reviews in food science and nutrition1979，4，： | 1 |
| 8 | On the time decay of solutions in one-dimensional theories of porous materials显示文摘 | Maga(n)a A Quintanilla R | | 0，，： | 1 |
| 9 | Proliferating cell nuclear antigen (PCNA):a dancer with many partners显示文摘 | Giovanni Maga Ulrich Hübscher | | 0，，： | 1 |
| 10 | Direct prediction of bioethanol yield in sugar beet pulp using Near Infrared Spectroscopy显示文摘 | C. Maga?a N. Nú?ez-Sánchez V.M. Fernández-Cabanás P. García A. Serrano D. Pérez-Marín J.M. Pemán E. Alcalde | 2011 | Bioresource Technology2011，，20： | 1 |
| 11 | M Interle ukin-2 does not overcome suppression of graft rejection by cyclospcrin A: effect of Cyclosporin A on T cell properties in vivo显示文摘 | Magae J Matsubara H Aotsuka N | 1996 | Cell Imm unol1996，173，： | 1 |
| 12 | On the time decay of solutions in porous-elasticity with quasi-static microvoids显示文摘 | Maga(n)a A Quintanilla R | | 0，，01： | 1 |
| 13 | Stability of beefy meaty peptide to pasteurization and sterilization temperature显示文摘 | Wang K Maga J A Bechtel P J | 1995 | Research Note1995，28，5： | 1 |
| 14 | Proliferating cell nuclear antigen(PCNA):a dancer with many partners显示文摘 | Maga G Hubscher U | 2003 | J Cell Sci2003，116，15： | 1 |
| 15 | Pyrazines in foods显示文摘 | Maga J Sizer C E | 1973 | CRC Critical Reviews in Food Technology1973，4，： | 1 |
| 16 | Appendectomy for appendicitis in patients with schizophrenia显示文摘 | Cooke BK Magas LT Virgo KS | 2007 | The American journal of surgery2007，193，1： | 1 |
| 17 | Proliferating cell nuclear antigen (PCNA) : A dancer with many partners显示文摘 | Maga G Hubscher U | 2003 | Journal of Cell Science2003，116，15： | 1 |
| 18 | Mushroom flavor 显示文摘 | Maga J A | 1981 | J Agric Food Chem1981，29，1： | 1 |
| 19 | A prospective study comparing paroxetine alone versus paroxetine plus sildenafil in patients with premature ejaculation显示文摘 | Salonia A Maga T Colombo R | 2002 | J Urol2002，168，6： | 1 |
| 20 | Mushroom flavor显示文摘 | MAGA J A | 1981 | Agric Food Chemistry1981，29，1： | 1 |
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