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| 1 | Beh et's disease complicated by multiple aseptic abscesses of the liver and spleen显示文摘Aseptic abscesses are an emergent entity and have been described in inflammatory bowel disease,especially in Crohn's disease,and in other diseases.However,aseptic abscesses associated with Beh et's disease are extremely rare.We report a Japanese male diagnosed with an incomplete type of Beh et's disease who developed multiple aseptic abscesses of the spleen and liver.In 2002,the spleen abscesses were accompanied by paroxysmal oral aphthous ulcers and erythema nodosum.As the patient's response to antibiotic treatment was inadequate,a splenectomy was performed.Severe inflammatory cell infiltration,largely of polymorphonuclear neutrophils,was observed without evidence of bacterial or fungal growth.Although the patient had no history of ocular symptoms or genital ulcers,a diagnosis of incomplete Beh et's disease was made according to the Japanese diagnostic criteria because of the presence of paroxysmal arthritis and epididymitis since 2002.In 2005,multiple liver abscesses developed with right hypochondrial pain and seemed to be attributed to Beh et's disease because the abscesses yielded negative results during a microbiologic investigation and failed to go into remission under antibiotic therapy.Oral prednisone(15 mg/d) was started in May 2006,and the abscesses dramatically disappeared 4 wk after treatment.Although the patient had a relapse of the liver abscesses in association with the tapering of prednisone,the augmentation of prednisone dosage yielded a response.The abscesses of the liver and spleen were strongly suggested to be attributed to Beh et's disease.Clinician should be aware of the existence of aseptic abscesses as uncommon manifestations of Beh et's disease. | Keisuke Maeshima Koji Ishii Megumi Inoue Katsuro Himeno Masataka Seike | 2013 | World Journal of Gastroenterology2013，19，20： | 3 |
| 2 | Tumstatin,an endothelial cell-specific inhibitor of protein synthesis显示文摘 | Maeshima Y Sudhakar A Lively J C | 2002 | Science2002，5552，295： | 1 |
| 3 | Extraeellular matrixderived peptide binds to alpha (v)beta(3) integrin and inhibits angiogenesis 显示文摘 | Maeshima Y Yerramalla UL Dhanabal M | 2001 | J Biol Chem2001，276，31： | 1 |
| 4 | Enteral nutrition rapidly reverses total parenteral nutrition-induced impairment of hepatic inununity in a murine mode显示文摘 | Omats J Fukatsu K Maeshima Y | 2009 | Clin Nutr2009，28，6： | 1 |
| 5 | characterization of major proteins in sweet potato tuberous roots 显示文摘 | Masayoshi maeshima | 1985 | phytochemistry1985，24，9： | 1 |
| 6 | Renal fibrosis:collagen composition and assembly regulates epithelial-mesenchymal transdifferentiation显示文摘 | Zeisberg M Bonner G Maeshima Y | 2001 | Am J Pathol2001，159，4： | 1 |
| 7 | Hepatocyte growth factor induces branching tubulogenesis in MDCK cells by modulating the activin-follistatin system显示文摘 | Maeshima A Zhang YQ Furukawa M | 2000 | Kidney Int2000，58，： | 1 |
| 8 | Extracellular matrix-derived peptide binds to alpha(v)beta(3) integrin and inhibits angiogenesis显示文摘 | Maeshima Y Yerramalla UL Dhanabal M | 2001 | J Biol Chem2001，276，31： | 1 |
| 9 | The ABC transporter AtPDR8 is a cadmium extrusion pump conferring heavy metal resistance 显示文摘 | Kim D Y Bovet L Maeshima M | 2007 | Plant Journal2007，50，2： | 1 |
| 10 | Extracellular matrix-derived peptide binds to alpha(v) beta(3) integrin and inhibits angiogenesis显示文摘 | Maeshima Y Yerramalla UL Dhanabal M | | 0，，： | 1 |
| 11 | The ABC transporter AtPDR8 is a cadmium extrusion pump con- ferring heavy metal resistance 显示文摘 | KIM D Y BOVET L MAESHIMA M | 2007 | Plant J2007，50，2： | 1 |
| 12 | Distinct antitumor properties of a type IV collagen domain derived from basement membrane显示文摘 | Maeshima Y Colorado PC Torre A | 2000 | J Biol Chem2000，275，21： | 1 |
| 13 | Decreased enteral stimulation altersmucosal immune chemokines显示文摘 | Hermsen JL Gomez FE Maeshima Y | 2008 | JPEN2008，32，1： | 1 |
| 14 | Retroperitonealschwannomas simulating adrenal tumors显示文摘 | Maeshima S Nakamura H Nishlkawa M | 1992 | Clin Imaging1992，16，2： | 1 |
| 15 | Identification of the anti-angiogenic site within vascular basement membranederived tumstatin 显示文摘 | Maeshima Y Manfredi M Reimer C | 2001 | J Biol Chem2001，276，15： | 1 |
| 16 | Tumstatin peptide, an inhibitor of angiogenesis, prevents glomerular hypertrophy in the early stage of diabetic nephropathy显示文摘 | Yamamoto Y Maeshima Y Kitayama H | 2004 | Diabetes2004，53，7： | 1 |
| 17 | Applications of high power density lithium ion batteries 显示文摘 | Horiba T Maeshima T Matsumura T | 2005 | J Power Sources2005，146，12： | 1 |
| 18 | Characterization of major pro-teins in sweet potato tuberous roots显示文摘 | Maeshima M?Sasaki T Asahi T | 1985 | Phytochemistry1985，24，： | 1 |
| 19 | Renal fibrosis:collagen composition and assembly regulates epithelial mesenchymal transdifferentitation显示文摘 | Zeisberq M Bonner G Maeshima Y | | 0，，04： | 1 |
| 20 | The role of pro-angiogenic factors and angiogenesis inhibitors in diabetic nephropathy显示文摘 | Maeshima Y Makino H | | 0，，09： | 1 |
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