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| 1 | 脑缺氧是影响严重颅脑创伤患者短期预后的独立危险因素(英文)显示文摘Background:Brain hypoxia(BH)can aggravate outcome after severe traumatic brain injury(TBI).Whether BH or reduced brain oxygen(Pbto2)is an independent outcome predictor or a marker of disease severity is not fully elucidated.Objective To analyze the relationship between Pbto2,intracranial pressure(ICP),and cerebral perfusion pressure(CPP)and to examine whether BH correlates with worse outcome independently of ICP and CPP.Methods We studied103patients | Oddo M Levine JM Mackenzie L Frangos S Feihl F Kasner SE Katsnelson M Pukenas B Macmurtrie E Maloney-Wilensky E Kofke WA Leroux PD | 2011 | 中华神经外科疾病研究杂志2011，10，5： | 21 |
| 2 | WONCA研究论文摘要汇编——慢性病管理计划(含职业疗法和理疗)能否减少老年人跌倒的风险?显示文摘背景运动和居家改造是预防跌倒的有效干预措施。慢性病管理(CDM)项目是全科医生开展这些干预措施的途径之一。这些研究的目的是对评估CDM,如职业疗法(OT)和理疗(PT)等对预防跌倒的效果和可行性。方法采用前后测试点研究设计,对在CDM中开展OT和PT分享的5项协同单元及全科医生管理计划进行评价。对干预前后的指标分别进行测量,对两家全科诊所的8例年龄≥75岁患者的转归进行评价。结果干预后2个月,患者的日常功能(P=0.04)、身体功能(P=0.01)及跌伤预防能力(P=0.01)得到了显著改善。患者对干预措施的依从性极佳。讨论在初级卫生保健机构开展跌倒预防干预是有效的,需要持续对干预措施进行推广,以确保有跌倒危险的老年人能从中受益。 | Mackenzie L Clemson L 周淑新 | 2014 | 中国全科医学2014，17，21： | 2 |
| 3 | Update on mesenchymal stem cell therapies for cartilage disorders显示文摘Cartilage disorders, including focal cartilage lesions, are among the most common clinical problems in orthopedic practice. Left untreated, large focal lesions may result in progression to osteoarthritis, with tremendous impact on the quality of life of affected individuals. Current management strategies have shown only a modest degree of success, while several upcoming interventions signify better outcomes in the future. Among these, stem cell therapies have been suggested as a promising new era for cartilage disorders. Certain characteristics of the stem cells, such as their potential to differentiate but also to support healing made them a fruitful candidate for lesions in cartilage, a tissue with poor healing capacity. The aim of this editorial is to provide an update on the recent advancements in the field of stem cell therapy for the management of focal cartilage defects. Our goal is to present recent basic science advances and to present the potential of the use of stem cells in novel clinical interventions towards enhancement of the treatment armamentarium for cartilage lesions. Furthermore, we highlight some thoughts for the future of cartilage regeneration and repair and to explore future perspectives for the next steps in the field. | Nikolaos K Paschos Mackenzie L Sennett | 2017 | World Journal of Orthopedics2017，8，12： | 2 |
| 4 | Fish immune system: A crossroads between innate and adaptive respons- es显示文摘 | TORT L BALASCH JC MACKENZIE S | 2003 | Inmunología2003，22，3： | 1 |
| 5 | The composition range of alumino silicate geopolymers显示文摘 | Fletcher R A Mackenzie K J D Nieholson C L | 2005 | J Eur Ceram Soc2005，25，： | 1 |
| 6 | Breast density in relation to risk of ductual carcinoma in situ of the breast in women undergoing screening mammography 显示文摘 | MacKenzie TA Tit us-Ernstoff L Vaeek PM | 2007 | Cancer Causes Contr2007，18，9： | 1 |
| 7 | Oral toxicity of carbon tetrachloride : acute, subacute and subchronic studies in rats显示文摘 | Bruckner J V MacKenzie W F Muralidhara S l | 1986 | Fundamental and Applied Toxicology1986，，6： | 1 |
| 8 | Dehrium probably induced by clarithromycin in a patient receiving flouxetine显示文摘 | POLLAK P T SKETRIS I S MACKENZIE S L | | 0，，05： | 1 |
| 9 | Detecting cognitive impairment in clients with mild stroke or transient ischemic attack attending a stroke prevention clinic显示文摘 | Mackenzie G Gould L Lreland S | | 0，，01： | 1 |
| 10 | Association of serum vitamin D level with diabetic polyneuropathy 显示文摘 | Chaychi L Mackenzie T Bilotta D | 2011 | Med Pract Rev2011，2，1： | 1 |
| 11 | Soil microclimate and nitrogen availability 10 years after mechanical site preparation in northern British Columbia 显示文摘 | MacKenzie M D Schmidt M G Bedford L | 2005 | Canadian Journal of Forest Research2005，35，8： | 1 |
| 12 | Renoprotective and anti hypertensive effects of combined valsartan and perindopril in progressive diabetic nephropathy in the transgenic(mRen-2) 27 rat显示文摘 | Otsm Mackenzie H S Tory J L | 2001 | Nephrol Dial Transplant2001，16，7： | 1 |
| 13 | Rapid secretion of interleukin-1 beta by microvesicle shedding显示文摘 | MacKenzie A Wilson H L Kiss-Toth E | 2001 | Immunity2001，15，5： | 1 |
| 14 | Glycosynthases: mutant glycosidases for oligosaccharide synthesis 显示文摘 | Mackenzie L F Wang Q Warren R A J | 1998 | Journal of the American Chemical Society1998，120，22： | 1 |
| 15 | Adenoviral vector-mediated gene transfer to primitive human hematopoietic progenitor cells:asessment of transduction and toxicity in long-term culture显示文摘 | MACKENZIE K L HACKETT N R CRYSTAL R G | 2000 | Blood2000，96，1： | 1 |
| 16 | Molecular parameters of maturation in the Toarcian shales,Paris,France Ⅰ:changes in the configuration of the acyclic isoprenoid alkanes,steranes and triterpanes显示文摘 | Mackenzie A S Patience R L Maxwell J R | 1980 | Geochimica et Cosmochimica Acta1980，44，： | 1 |
| 17 | Economics of CO2 capture using the calcium cycle with a pressurized fluidized bed combustor 显示文摘 | MACKENZIE A GRANATSTEIN D L ABANADES J C | 2007 | Energy & Fuels2007，21，2： | 1 |
| 18 | Nanoanalysis of very fine VN precipitates insteel显示文摘 | Mackenzie M Craven A J Collins C L | 2006 | Scipta Materialia2006，54，1： | 1 |
| 19 | Short- term hypertension is as- sociated with the development of atrial fibrillation substrate: a studyin an ovine hypertensive model 显示文摘 | Lau DH Mackenzie L Kelly DJ | 2010 | Heart Rhythm2010，7，3： | 1 |
| 20 | Impact of allopurinol use on u-rate concentration and cardiovascular outcome显示文摘 | Wei L Mackenzie IS Chen Y | 2011 | Br J Clin Phar-macol2011，71，4： | 1 |
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