维普中文期刊产品整合服务
68篇 您的检索式:作者名="Machon"
    题名 作者 年代 出处 被引量
1Estimation of net nitrogen flux between the atmosphere and a semi-natural grassland ecosystem in Hungary显示文摘Machon A Horvath L Weidinger T 2010European Journd of Soil Science2010,61,:1
2Co-directional replication-transcription conflicts lead to replication restart显示文摘Merrikh H Machon C Gringer WH 0,,7335:1
3No Genetic Diversity at Mo- lecular Markers and Strong Phenotypic Plasticity in Popula- tions of Ranunculus nodi? orus, an Endangered Plant Spe- cies in France 显示文摘Noel F Machon N Porcher E 2007Annals of Botany2007,99,:1
4Factors contributing to the uncertainty in circumaural earphone calibration for audiometric test 显示文摘RUIZ M FEUEREISEN B MACHON D RECUERO M 2005Applied Acoustics2005,66,9:1
5Gas-liquid dispersion with dual Rushton turbine impellers显示文摘Hudcova V Machon V Nienow A W 1989Biotechnol Bioeng1989,34,6:1
6Study of intracellular anabolism of 5-fluorouracil and incorporation in nucleic acids based on an LC-HRMS method显示文摘5-Fluorouracil(5-FU)is an anticancer drug extensively used for different cancers.Intracellular metabolic activation leads to several nucleoside and nucleotide metabolites essential to exert its cytotoxic activity on multiple cellular targets such as enzymes,DNA and RNA.In this paper,we describe the development of a method based on liquid chromatography coupled with high resolution mass spectrometry suitable for the simultaneous determination of the ten anabolic metabolites(nucleoside,nucleotide and sugar nucleotide)of 5-FU.The chromatographic separationwas optimized on a porous graphitic carbon column allowing the analysis of the metabolites of 5-FU as well as endogenous nucleotides.The detection was performed on an Orbitrap■tandem mass spectrometer.Linearity of the method was verified in intracellular content and in RNA extracts.The limit of detection was equal to 12 pg injected on column for nucleoside metabolites of 5-FU and 150 pg injected on column for mono-and tri-phosphate nucleotide metabolites.Matrix effect was evaluated in cellular contents,DNA and RNA extracts for nucleoside and nucleotides metabolites.The method was successfully applied to i)measure the proportion of each anabolic metabolite of 5-FU in cellular contents,ii)follow the consequence of inhibition of enzymes on the endogenous nucleotide pools,iii)study the incorporation of metabolites of 5-FU into RNA and DNA,and iv)to determine the incorporation rate of 5-FUrd into 18 S and 28 S sub-units of rRNA.Christelle Machon Frederic Catez Nicole Dalla Venezia Floriane Vanhalle Laetitia Guyot Anne Vincent Maxime Garcia Beatrice Roy Jean-Jacques Diaz Jerome Guitton 2021Journal of Pharmaceutical Analysis2021,11,1:1
7Estimation of nitrous oxide emission from Hungarian semi-arid sandy and loess grasslands~ effect of soil parameters, grazing, irrigation and use of fertilizer显示文摘Horvcith L Grosz B Machon A 2010Agriculture Ecosystems and Environment2010,139,:1
8Intake of total omega-3 fatty acids, eicosapentaenoic acid and docosa- hexaenoic acid and risk of coronary heart disease in the Spanish EPIC cohort study 显示文摘Amiano P Machon M Dorronsoro M 2014Nutr Metab Cardiovasc Dis2014,24,3:1
9On Achlysiella, a new genus of obese Pratylenchidae ( Nematoda: Tylenehoidea)显示文摘Hunt D J Bridge J Machon J E 1989Revue Nematology1989,12,4:1
10Characterization of mammalian orthologues of the Drosophila osa gene:cDNA cloning,expression,chromosomal localization,and direct physical interaction with Brahma chromatin-remodeling complex显示文摘Kozmik Z Machon O Kralova J 2001Genomics2001,73,2:1
11The mouse enhancer element D6 directs Cre recombinase activity in the neocortex and the hippocampus显示文摘van den Bout C J Machon O Backman M 2002Mech Dev2002,110,12:1
12The interaction of seasonality place of birth, genetic risk and subsequent schizophrenia in a high risk sample显示文摘Machon RA Mednick SA Schulsinger F 1983Br J Psychiatry1983,143,1:1
13A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice显示文摘Waaler J Machon O Tumova L 0,,11:1
14Open bite as a complication of total temporomandibar joint replacement: a case report 显示文摘Machon V Hirjak D Foltan R 2012Oral Surg Oral Med Oral Pathol Oral RacUol2012,114,4:1
15Paleofluids and recent fluids in the upper continental crust: Results from the German Continental Deep Drilling Program ( KTB ) 显示文摘Moller P Weise S M Ahhaus E Bach W Behr H J Borchardt R Brauer K Drescher J Erzinger J Faber E Hansen B T Horn E E Huenges E Kampf H Kessels W Kirsten T Landwehr D Lodemann M Machon L Pekdeger A Pielow H U Reutel C Simon K Walther J Weinlich F H Zimmer M 1997Journal of Geophysical Research1997,102,18:1
16Arthroscopic lysis and lavagein patients with temporomandibular anterior disc displacementwithout reduction显示文摘Machon V Sedy J Kllma K 2012Int J Oral Maxillofac Surg2012,41,1:1
17Adult schizophrenia following prenatal exposure to an influenza epidemic显示文摘Mednick SA Huttunen MO Machon RA 1988Arch Gen Psychiatry1988,45,:1
18Quantitative and reproducible two-dimensional gel analysis using Phoretix 2D Full显示文摘Machon P Dupree P 2001Electrophoresis2001,22,:1
19Autologous blood injec-tion for the treatment of chronic recurrent temporomandibularjoint dislocation显示文摘Machon V Abramowicz S Paska J 2009J Oral Maxillofac Surg2009,67,1:1
20Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon 显示文摘BACKMAN M MACHON O MYGLAND L 2005Dev Biol2005,279,1:1
返回顶部 每页显示:
共4页 首页 上一页 第1页 下一页 末页 /4 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费