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| 1 | Animal models for the study of hepatitis C virus infection and replication显示文摘Hepatitis C virus (HCV) hepatitis, initially termed non-A, non-B hepatitis, has become one of the leading causes of cirrhosis and hepatocellular carcinoma worldwide. With the help of animal models, our understanding of the virus has grown substantially from the time of initial discovery. There is a paucity of available animal models for the study of HCV, mainly because of the selective susceptibility limited to humans and primates. Recent work has focused modification of animals to permit HCV entry, replication and transmission. In this review, we highlight the currently available models for the study of HCV including chimpanzees, tupaia, mouse and rat models. Discussion will include methods of model design as well as the advantages and disadvantages of each model. Particular focus is dedicated to knowledge of pathophysiologic mechanisms of HCV infection that have been elucidated through animal studies. Research within animal models is critically important to establish a complete understanding of HCV infection, which will ultimately form the basis for future treatments and prevention of disease. | Kristin L MacArthur Catherine H Wu George Y Wu | 2012 | World Journal of Gastroenterology2012，18，23： | 6 |
| 2 | An equilibrium theory of insular zoogeography显示文摘 | MacArthur R H Wilson E O | 1963 | Evolution1963，179，4： | 2 |
| 3 | The limiting similarly,convergence and divergence of coexisting species显示文摘 | MACARTHUR R H Levins R | 1967 | The American Naturalist1967，101，： | 1 |
| 4 | Graphical representation and stability conditions of predator-prey interactions显示文摘 | ROSENZWEIG M L MACARTHUR R H | 1963 | Amer Nat1963，47，： | 1 |
| 5 | Species packing and competitive equilibrium for many species显示文摘 | MACARTHUR R H | 1970 | Theoretical Population Biology1970，，1： | 1 |
| 6 | A fuzzy discrete event system approach to determining optimal HIV/AIDS treatment regimens显示文摘 | Ying H Lin F Macarthur R D | 2006 | IEEE Transactions on Information Technology in Biomedicine2006，10，4： | 1 |
| 7 | The limiting similarity, convergence and divergence of coexisting species显示文摘 | Macarthur R H Levins R | 1967 | The American Naturalist1967，101，： | 1 |
| 8 | The limiting similarity,convergence and divergence of coexisting species显示文摘 | MACARTHUR R H LEVINS R | 1967 | The American Naturalist1967，101，： | 1 |
| 9 | The limiting similarity,convergence,and divergence of coexisting species显示文摘 | MACARTHUR R H LEVINS R | 1967 | American Naturalist1967，101，： | 1 |
| 10 | Decision making in fuzzy discrete event systems 显示文摘 | Lin F Ying H MacArthur R D | 2007 | Information Sciences2007，177，： | 1 |
| 11 | Foliage profile by vertical measurements显示文摘 | Robert H Macarthur Horn H S | | Ecology0，50，5： | 1 |
| 12 | The Limiting Similarity Convergenee and Divergence of Coexisting显示文摘 | MacArthur R H Levins R | 1967 | The American Naturalist1967，101，： | 1 |
| 13 | Exercise for vasomo-tor menopausal symptoms 显示文摘 | Daley A Stokes-Lampard H Macarthur C | 2011 | Cochrane Database Syst Rev2011，11，00： | 1 |
| 14 | The limiting similarity convergence and divergence of coexisting species显示文摘 | LEVINS R | 1967 | The American Naturalist1967，101，： | 1 |
| 15 | Roles for FGF8 in the induction,initiation,and maintenance of chick limb development显示文摘 | Crossley P H Minowada G MacArthur C A | | 0，，01： | 1 |
| 16 | On the relation between habitat selection and species diversity 显示文摘 | MacArthur R Recher H and Cody M | 1966 | The American Naturalist1966，100，： | 1 |
| 17 | Hypothermia and acidosis worsen coagulopathy in the patient requiring massive transfusion显示文摘 | Ferrara A MacArthur J Wright H | 1990 | Am J Surg1990，160，5： | 1 |
| 18 | Competition among fugitive species in a harlequin environment显示文摘 | Horn H S MacArthur R H | 1972 | Ecology1972，5，： | 1 |
| 19 | Decision making in fuzzy discrete event systems显示文摘 | Lin F Ying H MacArthur R D | 2007 | Information Sciences2007，177，18： | 1 |
| 20 | Fluctuations of animal populations and a measure of community stability 显示文摘 | MacArthur R H | 1955 | Ecology1955，36，： | 1 |
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