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| 1 | Autoimmune liver serology:Current diagnostic and clinical challenges显示文摘Liver-related autoantibodies are crucial for the correct diagnosis and classification of autoimmune liver diseas-es(AiLD),namely autoimmune hepatitis types 1 and 2(AIH-1 and 2),primary biliary cirrhosis(PBC),and the sclerosing cholangitis variants in adults and children.AIH-1 is specified by anti-nuclear antibody(ANA) and smooth muscle antibody(SMA).AIH-2 is specified by antibody to liver kidney microsomal antigen type-1(anti-LKM1) and anti-liver cytosol type 1(anti-LC1).SMA,ANA and anti-LKM antibodies can be present in de-novo AIH following liver transplantation.PBC is specified by antimitochondrial antibodies(AMA) react-ing with enzymes of the 2-oxo-acid dehydrogenase complexes(chiefly pyruvate dehydrogenase complex E2 subunit) and disease-specific ANA mainly react-ing with nuclear pore gp210 and nuclear body sp100.Sclerosing cholangitis presents as at least two variants,first the classical primary sclerosing cholangitis(PSC) mostly affecting adult men wherein the only(and non-specific) reactivity is an atypical perinuclear antineutro-phil cytoplasmic antibody(p-ANCA),also termed peri-nuclear anti-neutrophil nuclear antibodies(p-ANNA) and second the childhood disease called autoimmune sclerosing cholangitis(ASC) with serological features resembling those of type 1 AIH.Liver diagnostic serol-ogy is a fast-expanding area of investigation as new purified and recombinant autoantigens,and automatedtechnologies such as ELISAs and bead assays,become available to complement(or even compete with) tradi-tional immunofluorescence procedures.We survey for the first time global trends in quality assurance impact-ing as it does on(1) manufacturers/purveyors of kits and reagents,(2) diagnostic service laboratories that fulfill clinicians' requirements,and(3) the end-user,the physician providing patient care,who must properly interpret test results in the overall clinical context. | Dimitrios P Bogdanos Diego Vergani Pietro Invernizzi Ian R Mackay | 2008 | World Journal of Gastroenterology2008，14，21： | 40 |
| 2 | 常规脂蛋白检测和载脂蛋白在心血管病预测中的比较显示文摘总胆固醇和高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)测量值对于心血管病风险评估至关重要,但对于其他脂质用于风险预测的效用一直存在争议。该研究纳入来自英国生物银行(Biobank)的无基线心血管病、未服用他汀类药物、有相关的脂质指标(n=346 686)的受试者。 | Welsh C Celis-Morales CA Brown R Mackay DF Lewsey J Mark PB Gray SR Ferguson LD Anderson JJ Lyall DM Cleland JG Jhund PS Gill J MR Pell JP Sattar N Welsh P 刘青(译) 叶鹏(摘、审校) | 2019 | 中华高血压杂志2019，27，7： | 10 |
| 3 | Droplet size distribu- tions in chemical dispersion of oil spills:towards a mathe- matical model显示文摘 | Daling P S Mackay D Mackay N | 1990 | Oil and Chemical Pollution1990，7，3： | 1 |
| 4 | Performance assessment of a nuclear waste repository: Upscaling coupled hydro-mechanical properties for far-field transport analysis 显示文摘 | Blum P Mackay R Riley M S Knight J L | 2005 | International Journal of Rock Mechanics and Mining Sciences2005，42，56： | 1 |
| 5 | The lower-generation polypropylenimine dendrimers are effective gene-transfer agents 显示文摘 | ZINSELMEYER B H MACKAY S P SCHATZLEIN A G | 2002 | Pharm Res2002，9，7： | 1 |
| 6 | Special distribution of acid-volatile sulfide concerntration and metal bioavailability in mangrove sendiments from the Brisbane River,Australia显示文摘 | Mackey A P Mackay S | 1996 | Enviromental Pollution1996，93，2： | 1 |
| 7 | Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations显示文摘 | Mackay F Woodcock SA Lawton P | 1999 | J Exp Med1999，190，11： | 1 |
| 8 | Urban groundwater base- flow influence upon inorganic river-water quality: the river tame headwaters catchment in the city of Birmingham, UK 显示文摘 | RIVETT M O ELLIS P A MACKAY R | 2011 | Journal of Hydrology2011，400，12： | 1 |
| 9 | Chemorheology of thermoset-an overview 显示文摘 | Halley P J Mackay M E | 1996 | Polymer Engineering and Science1996，36，5： | 1 |
| 10 | Investment and competition显示文摘 | Akdogu E Mackay P | 2008 | Journal of Financial Quantitative Analysis2008，43，： | 1 |
| 11 | Chemorheology of t her mal: An overview显示文摘 | all ey P J Mackay M E | 1996 | Poly mer Engineeri ng and Science1996，36，5： | 1 |
| 12 | Differentiating infection from vaccination in foot-and-mouth disease using a panel of recombinant non-structural proteins in ELISA显示文摘 | Mackay D K J Forsyth M A Davies P R | 1997 | Vaccine1997，16，5： | 1 |
| 13 | How Does Industry Affect Firm Financial Structure? 显示文摘 | MacKay P Phillips G M | 2005 | Review of Financial Studies2005，18，4： | 1 |
| 14 | Sparse graph codes for quantum error-correction显示文摘 | Mackay D Mitchison G Mcfadden P | 2004 | IEEE Transactions Information Theory2004，50，： | 1 |
| 15 | Chemorheology of thermosets-An overview 显示文摘 | Halley P J Mackay M E | 1996 | Polym Eng Sci1996，36，5： | 1 |
| 16 | BAFF, a no- vel tigand of the tumor necrosis factor family, stimulates B cell growth显示文摘 | SCHNEIDER P MACKAY F STEINER V | 1999 | J ExpMed1999，189，11： | 1 |
| 17 | Differentiating infection from vaccination in foot-and-mouth disease using a panel of recombinant,non-structural proteins in ELISA显示文摘 | Mackay D K Forsyth M A Davies P R | 1998 | Vaccine1998，16，5： | 1 |
| 18 | BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth 显示文摘 | Schneider P MacKay F Steiner V | 1999 | J Exp Med1999，189，11： | 1 |
| 19 | Second-line or subsequent systemic therapy for recurrent or progressive non-small cell lung cancer:a systematic review and practice guideline显示文摘 | Noble J Ellis P M Mackay J A Evans W K | 2006 | J Thorac Oncol2006，1，： | 1 |
| 20 | TACI, an enigmatic BAFF/APRIL rece- ptor, with new unappreciated biochemical and biological prope- rties 显示文摘 | Mackay F Schneider P | 2008 | Cytokine Growth Factor Rev2008，19，34： | 1 |
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