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| 1 | 常规脂蛋白检测和载脂蛋白在心血管病预测中的比较显示文摘总胆固醇和高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)测量值对于心血管病风险评估至关重要,但对于其他脂质用于风险预测的效用一直存在争议。该研究纳入来自英国生物银行(Biobank)的无基线心血管病、未服用他汀类药物、有相关的脂质指标(n=346 686)的受试者。 | Welsh C Celis-Morales CA Brown R Mackay DF Lewsey J Mark PB Gray SR Ferguson LD Anderson JJ Lyall DM Cleland JG Jhund PS Gill J MR Pell JP Sattar N Welsh P 刘青(译) 叶鹏(摘、审校) | 2019 | 中华高血压杂志2019,27,7: | 10 |
| 2 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014,5,2: | 5 |
| 3 | The role of chemokine receptors in primary effector and memory immune responses显示文摘 | Sallusto F Mackay C R Lanzavecchia A | | 0,,: | 3 |
| 4 | Transcribed her-eroplasmic repeated sequences in the porcine mitochondrial DNA D-loop region显示文摘 | Ghlvlzzani SC Mackay SL Madsen C S | 1993 | J Mol Evol1993,37,1: | 1 |
| 5 | Bayesian interpolation显示文摘 | | 1992 | Neural Computation1992,4,41: | 1 |
| 6 | Variational Gaussian process classifiers显示文摘 | GIBBS M N MACKAY D J C | 2000 | IEEE Transactions on Neural Net- works2000,11,6: | 1 |
| 7 | Good error-correcting codes based on very sparse matrices显示文摘 | MACKAY D J C | 1999 | IEEE Trans Information Theory1999,45,2: | 1 |
| 8 | Bayesian Neural Network Model for Aaustenite Formation in Steels显示文摘 | GAVARD L BHADESHIA H K D H MACKAY D J C | 1996 | Mater Sci Tech1996,12,7: | 1 |
| 9 | Good error correcting codes based on very sparse matrices显示文摘 | MACKAY D J C | 1999 | IEEE Transaction on Inform Theory1999,45,2: | 1 |
| 10 | Multilineage paential of adult human mesenchymal stem cells 显示文摘 | PITFENGER M F MACKAY A M BECK S C | 1999 | Science1999,284,5411: | 1 |
| 11 | Bayesian interpolation显示文摘 | MACKAY DAVID J C | 1992 | Neural Computation1992,11,4: | 1 |
| 12 | Good Error-Correcting Codes Based on Very Sparse Matrices显示文摘 | MacKay DJ C | 1999 | IEEE Transactions on Information Theory1999,45,39: | 1 |
| 13 | Near Shannon limit performance of low density parity check codes 显示文摘 | MACKAY D J C NEAL R M | 1997 | Electronics Letters1997,33,6: | 1 |
| 14 | Near Shannon limit performance of low density parity check codes 显示文摘 | Mackay D J C Neal R M | 1996 | Electronics Letters1996,33,6: | 1 |
| 15 | Multilineage potential of adult human mesenchymal stem cells显示文摘 | Pittenger M F Mackay A M Beck S C | | 0,,5411: | 1 |
| 16 | Near Shannon limit performance of low density parity check codes显示文摘 | MACKAY D J C and NEAL R M | 1996 | Electronics Letters1996,32,18: | 1 |
| 17 | Comparison of constructions of irregular Gallager codes 显示文摘 | MacKay D J C Wilson S T Matthew C D | 1999 | IEEE Trans Commun1999,47,10: | 1 |
| 18 | T follicular helper (TFH) cells in normal and dysregulated immune responses 显示文摘 | King C Tangye SG Mackay CR | 2008 | Annu Rev Immunol2008,26,: | 1 |
| 19 | Cocaine abusers have reduced auditory P50 amplitude and suppression compared to both normal controls and alcoholics显示文摘 | Biggins C MacKay S | 1996 | Biol Psychiatry1996,39,: | 1 |
| 20 | The Evidence Framework Applied to Classification Networks显示文摘 | MACKAY D J C | 1992 | Neural Computation1992,4,5: | 1 |