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| 1 | Cytokines as biochemical markers for knee osteoarthritis显示文摘Osteoarthritis(OA) is a debilitating degenerative joint disease particularly affecting weightbearing joints within the body, principally the hips and knees. Current radiographic techniques are insufficient to show biochemical changes within joint tissue which can occur many years before symptoms become apparent. The need for better diagnostic and prognostic tools is heightened with the prevalence of OA set to increase in aging and obese populations. As inflammation is increasingly beingconsidered an important part of OAs pathophysiology, cytokines are being assessed as possible candidates for biochemical markers. Cytokines, both pro- and antiinflammatory, as well as angiogenic and chemotactic, have in recent years been studied for relevant characteristics. Biochemical markers show promise in determination of the severity of disease in addition to monitoring of the efficacy and safety of disease-modifying OA drugs, with the potential to act as diagnostic and prognostic tools. Currently, the diagnostic power of interleukin(IL)-6 and the relationship to disease burden of IL-1β, IL-15, tumor necrosis factor-α, and vascular endothelial growth factor make these the best candidates for assessment. Grouping appropriate cytokine markers together and assessing them collectively alongside other bone and cartilage degradation products will yield a more statistically powerful tool in research and clinical applications, and additionally aid in distinguishing between OA and a number of other diseases in which cytokines are known to have an involvement. Further large scale studies are needed to assess the validity and efficacy of current biomarkers, and to discover other potential biomarker candidates. | Thomas Mabey Sittisak Honsawek | 2015 | World Journal of Orthopedics2015，6，1： | 38 |
| 2 | Laparoscopic ventral mesh rectopexy in the management of solitary rectal ulcer syndrome: a cause for optimism?显示文摘 | A. H. Badrek‐Amoudi T. Roe K. Mabey H. Carter A. Mills A. R. Dixon | 2013 | Colorectal Dis2013，，5： | 2 |
| 3 | The burden and determinants of reproductive tract infections in India:a population based study of women in Goa, India 显示文摘 | Patel V Weiss HA Mabey D | 2006 | Sex Transm Infect2006，82，： | 1 |
| 4 | Azithromycin in control of trachoma显示文摘 | Schacher J West SK Mabey D | 1999 | Lancet1999，354，： | 1 |
| 5 | Azithromycin in control of trachoma显示文摘 | Schachter J West SK Mabey D | 1999 | Lancet1999，354，： | 1 |
| 6 | Approaches to the control of sexually transmitted infections in developing countries: old problems and modern challenges显示文摘 | Mayaud P Mabey D | 2004 | Sex Transm Infect2004，80，3： | 1 |
| 7 | Vitamin D and spine surgery显示文摘Vitamin D is crucial for musculoskeletal health, maintenance, and function. Vitamin D insufficiency is common among patients undergoing spine surgery and the ideal vitamin D level for spine surgery has yet to be investigated. There is a high prevalence of hypovitaminosis D in patients with musculoskeletal pain regardless of surgical intervention. With the frequency and costs of spine surgery increasing, it is imperative that efforts are continued to reduce the impact on patients and healthcare services. Studies into vitamin D and its associations with orthopaedic surgery have yielded alarming findings with regards to the prevalence of vitamin D deficiency. Importantly, altered vitamin D status also contributes to a wide range of disease conditions. Therefore, future investigations are still essential for better understanding the relationship between vitamin D and spine surgery outcomes. Whilst further research is required to fully elucidate the extent of the effects of hypovitaminosis D has on surgical outcomes, it is strongly advisable to reduce the impacts by appropriate vitamin D supplementation of deficient and at-risk patients. | Thomas Mabey Weerasak Singhatanadgige Wicharn Yingsakmongkol Worawat Limthongkul Sittisak Honsawek | 2016 | World Journal of Orthopedics2016，7，11： | 1 |
| 8 | A Sunmmary of Measurements of Steady and Oscillatory Pressures on a Rectangular Wing 显示文摘 | Mabey D G Welsh B L Pyne C R | 1988 | Aeronautical Journal1988，92，911： | 1 |
| 9 | Supplementation of corn-soybean meal diet with manganese ,copper,zine form organic sources improves egghell quality in aged laying bens 显示文摘 | Mabei I Rappc C Bain M M | 2003 | Pouh Sci J2003，82，： | 1 |
| 10 | Prospective,multi-centre clinic-based evaluation of four rapid diagnostictests for syphilis显示文摘 | Mabey D Peeling RW Ballard R | 2006 | Sex Transm Infect2006，82，5： | 1 |
| 11 | Syphilis显示文摘 | Peeling RW Mabey DC | 2004 | Nat Rev Microbiol2004，2，6： | 1 |
| 12 | Supplementation of corn-siybean meal diet with manganese,copper,zine from organic sourees im- proves eggshell quality in aged laying hens显示文摘 | MABEI RAPPC BAINMM | 2003 | Pouh Sei2003，82，： | 1 |
| 13 | Photolysis of polycyclic aromatic hydrocarbons in water显示文摘 | Mill T Mabey W R Lan B Y | 1981 | Chemosphere1981，10，1112： | 1 |
| 14 | On the prospects for increasing dynamic lift显示文摘 | Mabey D G | 1988 | Aeronautical Journal1988，92，3： | 1 |
| 15 | Approaches to the control of sexually transmitted infections in developing countries:role problems and modern challenges显示文摘 | Mayaud P Mabey D | 2004 | Sexually Transmitted Infections2004，80，3： | 1 |
| 16 | Angiogenic cytokine ex- pression profiles in plasma and synovial fluid of primary knee oste- oarthritis显示文摘 | Mabey T Honsawek S Saetan N | 2014 | Int Orthop2014，38，9： | 1 |
| 17 | Chlamydial infections显示文摘 | Blanchard T J Mabey D C | 1994 | Br J Clin Pract1994，48，4： | 1 |
| 18 | Tropical infectiousdiseases:Diagnostics for the developing world显示文摘 | Mabey D Peeling RW Ustianowski A | 2004 | Nat Rev Microbio2004，2，3： | 1 |
| 19 | Chlamydial infections显示文摘 | Blanchard T J Mabey D C | 1994 | Br J Clin Praet1994，48，4： | 1 |
| 20 | Interventions for trachoma trichiasis显示文摘 | MABEY D HATT S | 2006 | Cochrane Database Syst Rev2006，19，00： | 1 |
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