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| 1 | Ceruloplasmin-ferroportin system of iron traffic in vertebrates显示文摘Safe trafficking of iron across the cell membrane is a delicate process that requires specific protein carriers. While many proteins involved in iron uptake by cells are known, only one cellular iron export protein has been identified in mammals: ferroportin(SLC40A1). Ceruloplasmin is a multicopper enzyme endowed with ferroxidase activity that is found as a soluble isoform in plasma or as a membrane-associated isoform in specific cell types. According to the currently accepted view, ferrous iron transported out of the cell by ferroportin would be safely oxidized by ceruloplasmin to facilitate loading on transferrin. Therefore, the ceruloplasminferroportin system represents the main pathway for cellular iron egress and it is responsible for physiological regulation of cellular iron levels. The most recent findings regarding the structural and functional features of ceruloplasmin and ferroportin and their relationship will be described in this review. | Giovanni Musci Fabio Polticelli Maria Carmela Bonaccorsi di Patti | 2014 | World Journal of Biological Chemistry2014，5，2： | 6 |
| 2 | Diagnostic utility of faecal biomarkers in patients with irritable bowel syndrome显示文摘Irritable bowel syndrome(IBS)is a common functional gastrointestinal(GI)disorder characterized by unspecific symptoms.In clinical practice it is crucial to distinguish between non-inflammatory functional problems and inflammatory,malignant or infectious diseases of the GI tract.Differentiation between these involves the use of clinical,radiological,endoscopic,histological and serological techniques,which are invasive,expensive,time-consuming and/or hindered by inaccuracies arising from subjective components.A range of faecal markers now appears to have the potential to greatly assist in the differentiation of inflammatory bowel disease(IBD)and IBS.Faecal markers of neutrophil influx into the mucosa are reliable indicators of intestinal inflammation and their role has been mainly studied in discriminating IBD from non-IBD conditions(including IBS)rather than organic from non-organic diseases.Phagocytespecific proteins of the S100 family(S100A12,calprotectin)are amongst the most promising faecal biomarkers of inflammation.Faecal leukocyte degranulation markers(lactoferrin,polymorphonuclear elastase and myeloperoxidase)have also been suggested as diagnostic tools for the differentiation of IBD and IBS.More recently,additional proteins,including granins,defensins and matrix-metalloproteases,have been discussed as differential diagnostic markers in IBD and IBS.In this review,some of the most promising faecal markers,which have the potential to differentiate IBD and IBS and to advance diagnostic practices,will be discussed. | Jan Dabritz Jason Musci Dirk Foell | 2014 | World Journal of Gastroenterology2014，20，2： | 4 |
| 3 | Study of the volatile compounds useful for the characterisation of fresh and frozen-thawed cultured gilthead sea bream fish by solid-phase microextraction gas chromatography–mass spectrometry显示文摘 | J. Iglesias I. Medina F. Bianchi M. Careri A. Mangia M. Musci | 2009 | Food Chemistry2009，，4： | 2 |
| 4 | Fish and food safety: Determination of formaldehyde in 12 fish species by SPME extraction and GC–MS analysis显示文摘 | F. Bianchi M. Careri M. Musci A. Mangia | 2005 | Food Chemistry2005，，3： | 2 |
| 5 | Expression of a dominant negative mutant of the FGFreceptor disrupts mesoderm formation in Xenopus embryos显示文摘 | 5,Amaya E Musci TJ Kirschner MW | 1991 | Cell1991，66，： | 1 |
| 6 | Molecular methods for diagno- sis of infective endocarditis显示文摘 | Moter A Musci M Schmiedel D | 2010 | Curr Infect Dis Rep2010，12，4： | 1 |
| 7 | Optical observations of space debris in GEO and in high-eccentric orbits显示文摘 | Schildknecht T Musci R Ploner M | 2004 | Advances in Space Research2004，34，5： | 1 |
| 8 | Preeclampsia:an endothelial cell disorder显示文摘 | Roberts JM Taylor RN Musci TJ | 1989 | Am J Obstet Gynecol1989，161，5： | 1 |
| 9 | Fish and food safety: determination of formaldehyde in 12 fish species by SPME extraction and GC-MS analysis显示文摘 | BIANCHI F CARERI M MUSCI M | 2007 | Food Chemistry2007，100，： | 1 |
| 10 | Stentless bio prosthesis centre experience in a subgroup of 255 patients treated with the Shelhighsurgical therapy in patients with active infective endocarditis: seven-year Single 显示文摘 | Musci M Siniawski H Pasic M | 2008 | Eur J Cardiothorac Surg2008，34，41： | 1 |
| 11 | Fish and food safety: determination of formaldehyde in 12 fish species by SPME extraction and GC-MS analysis显示文摘 | BIANCHI F CARERI M MUSCI M | 2007 | Food Chemistry2007，100，3： | 1 |
| 12 | Fish and food safety: determination of formaldehyde in 12 fish species by SPME extraction and GC- MS analysis 显示文摘 | Bianchi F Careri M Musci M | 2007 | Food Chemistry2007，100，3： | 1 |
| 13 | Mitral valve repair for infective endocarditis in chidren 显示文摘 | Delma Walter EM Musci M Nagdyman N | 2007 | Am Thorac Surg2007，84，6： | 1 |
| 14 | Applications of liquid chromatography-mass spectrometry interfacing systems in food analysis: pesticide, drag and toxic substance residues显示文摘 | Careri M Mangia A Musci M | 1996 | J Chromatogr A1996，，727： | 1 |
| 15 | The tumor suppressor Smadd/DPC4as a central mediator of Smad fuction 显示文摘 | Zhang Y Musci T Derynck R | 1997 | Curr Biol1997，7，4： | 1 |
| 16 | Fish and food safety : Determination of formaldehyde in 12 fish species by SPME extraction and GC-MS analysis显示文摘 | Bianchi F Careri M Musci M | 2007 | Food Chemistry2007，100，10： | 1 |
| 17 | Fish and food safety: determination of formaldehyde in 12 fish species by SPME extraction and GC- MS analysis显示文摘 | Bianchi F Careri M Musci M | 2007 | Food Chem2007，100，： | 1 |
| 18 | Preeclampsia: a endothelial cell disorder显示文摘 | Taylor RN Musci TG | 1989 | Am J Obstet Gynecol1989，161，： | 1 |
| 19 | Clinical utility and cost of noninvasive prenatal testing with cf DNA analysis in high-risk women based on a US population显示文摘 | Song K Musci TJ Caughey AB | 2013 | J Matern Fetal Neonatal Med2013，26，12： | 1 |
| 20 | Predicting self - care with patients and family members' affective states and family functioning显示文摘 | Musci EC Dodd MJ | 1990 | Oncol Nurs Forum1990，17，3： | 1 |
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