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| 1 | Strategies for combating bacterial biofilm infections显示文摘Formation of biofilm is a survival strategy for bacteria and fungi to adapt to their living environment, especially in the hostile environment. Under the protection of biofilm, microbial cells in biofilm become tolerant and resistant to antibiotics and the immune responses, which increases the difficulties for the clinical treatment of biofilm infections. Clinical and laboratory investigations demonstrated a perspicuous correlation between biofilm infection and medical foreign bodies or indwelling devices. Clinical observations and experimental studies indicated clearly that antibiotic treatment alone is in most cases insufficient to eradicate biofilm infections. Therefore, to effectively treat biofilm infections with currently available antibiotics and evaluate the outcomes become important and urgent for clinicians. The review summarizes the latest progress in treatment of clinical biofilm infections and scientific investigations, discusses the diagnosis and treatment of different biofilm infections and introduces the promising laboratory progress,which may contribute to prevention or cure of biofilm infections. We conclude that, an efficient treatment of biofilm infections needs a well-established multidisciplinary collaboration, which includes removal of the infected foreign bodies, selection of biofilm-active,sensitive and well-penetrating antibiotics, systemic or topical antibiotic administration in high dosage and combinations, and administration of anti-quorum sensing or biofilm dispersal agents. | Hong Wu Claus Moser Heng-Zhuang Wang Niels Hφiby Zhi-Jun Song | 2015 | International Journal of Oral Science2015，7，1： | 27 |
| 2 | Residual or recurrent cerebellar low-grade glioma in children after tumor resection: is re-treatment needed? A single center experience from 1983 to 2003显示文摘 | Benesch M Eder HG Sovinz P Raith J Lackner H Moser A Urban C | 2006 | 中国神经肿瘤杂志2006，4，3： | 15 |
| 3 | Psychosocial issues in evidence-based guidelines on inflammatory bowel diseases: A review显示文摘AIM:To study statements and recommendations on psychosocial issues as presented in international evidence-based guidelines on the management of inflammatory bowel diseases(IBD).METHODS:MEDLINE,guidelines International Network,National Guideline Clearing House and National Institute for Health and Care Excellence were searched from January 2006 to June 30,2013 for evidencebased guidelines on the management of IBD.RESULTS:The search yielded 364 hits.Thirteen guidelines were included in the review,of which three wereprepared in Asia,eight in Europe and two in the United States.Eleven guidelines made statements and recommendations on psychosocial issues.The guidelines were concordant in that mental health disorders and stress do not contribute to the aetiology of IBD,but that they can influence its course.It was recommended that IBD-patients should be screened for psychological distress.If indicated,psychotherapy and/or psychopharmacological therapy should be recommended.IBDcentres should collaborate with mental health care specialists.Tobacco smoking patients with Crohn’s disease should be advised to quit.CONCLUSION:Patients and mental health specialists should be able to participate in future guideline groups to contribute to establishing recommendations on psychosocial issues in IBD.Future guidelines should acknowledge the presence of psychosocial problems in IBD-patients and encourage screening for psychological distress. | Winfried Huser Gabriele Moser Petra Klose Antonina Mikocka-Walus | 2014 | World Journal of Gastroenterology2014，20，13： | 14 |
| 4 | Second European evidence-based consensus on the diagnosis and management of ulcerative colitis: Special situations显示文摘 | Gert Van Assche Axel Dignass Bernd Bokemeyer Silvio Danese Paolo Gionchetti Gabriele Moser Laurent Beaugerie Fernando Gomollón Winfried H?user Klaus Herrlinger Bas Oldenburg Julian Panes Francisco Portela Gerhard Rogler Jürgen Stein Herbert Tilg Simon Tra | 2012 | Journal of Crohn’s and Colitis2012，，： | 4 |
| 5 | Regulation of putative fatty acid transpoters and acyl-CoA synthetase in liver and adipose tissue in ob/ob Mice显示文摘 | Memon R A Fuller J Moser A H | 1999 | Diabetes1999，48，2： | 2 |
| 6 | Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth 显示文摘 | Hoiby N Krogh J H Moser C | 2001 | Microbes Infect2001，3，1： | 1 |
| 7 | Solid-state dye-sensitized mesoporous TiO2 solar cells with high photon-to-electron conversion efficiencies显示文摘 | Bach U Lupo D Comte P Moser J E Weiss(o)rtel F Salbeck J Spreitzer H Gr(a)tzel M | | 0，，： | 1 |
| 8 | Postoperative delirium:risk factors,prophylaxis and treatment显示文摘 | Gallinat J Moller H Moser RL | 1999 | Anaesthesist1999，48，8： | 1 |
| 9 | Endocardial fibroelastosis of the heart显示文摘 | Steger C M Antretter H Moser P L | 2012 | Lancet2012，10，7： | 1 |
| 10 | Endocardial fibroelastosis of the heart显示文摘 | Steger CM Antretter H Moser PL | 2012 | Lancet2012，379，9819： | 1 |
| 11 | A duhamel integral based approachto one-dimensional wave propagation analysis in layered media显示文摘 | Moser W Antes H Beer G | 2005 | Comput Mech2005，35，2： | 1 |
| 12 | Analysis and quantization of free ceramide containing nonhydroxy and 2 - hydroxy fatty acids and phytosphingosine by high performance liquid chro- matography 显示文摘 | Iwamori M Costello C Moser H | 1979 | Journal of Lipid Research1979，20，： | 1 |
| 13 | Entwieklung und validierung einer networkingskala显示文摘 | Wolff H G and Moser K | 2006 | Diagnostiea2006，52，4： | 1 |
| 14 | Structural, chemical, and electrical eharacterisation of reactively sputtered WSx thin films显示文摘 | Regula M Ballif C Moser J H | 1996 | Thin Solid Films1996，280，： | 1 |
| 15 | Hypocholesterolemia in chronic anemias with increased erythropoietic activity显示文摘 | Shalev H Kapelushnik J Moser A | 2007 | Am J Hematol2007，82，3： | 1 |
| 16 | An indirect ELISA for the detection of antibodies against porcine reproductive and respiratory syndrome virus using recombinant nucleocapsid protein as antigen显示文摘 | Denac H Moser C Tratsch J D | 1997 | J Virol Methods1997，65，2： | 1 |
| 17 | Genome-wide linkage and QTL mapping in porcine F2 families 显示文摘 | Geldermarm H Muller E Moser G | 2003 | J Anim Breed Genet2003，120，： | 1 |
| 18 | Landscape patch shape complexity as an effective measure for plant species richness in rural landscapes显示文摘 | MOSER D ZECHMEISTER H G PLUTZAR C | 2002 | Landscape Ecology2002，17，： | 1 |
| 19 | Primary duodenalcarcinoma showing divergent growth patterns as determined by microdissection-based mutational genotyping显示文摘 | Cheung O Kandil H Moser AJ | 2003 | Arch Pathol Lab Med2003，127，7： | 1 |
| 20 | Coll(dbbip) 22+complex rivals tri-iodide/Iodide redox mediator in dyesensitized photovoltaic cells显示文摘 | Nusbaumer H Jacques-E Moser J E | 2001 | Phys Chem B2001，105，10： | 1 |
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