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| 1 | Outcomes of liver transplantation in patients with hepatorenal syndrome显示文摘Hepatorenal syndrome(HRS) plays an important role in patients with liver cirrhosis on the wait list for liver transplantation(LT). The 1 and 5-year probability of developing HRS in cirrhotic with ascites is 20% and 40%, respectively. In this article, we reviewed current concepts in HRS pathophysiology, guidelines for HRS diagnosis, effective treatment options presently available, and controversies surrounding liver alone vs simultaneous liver kidney transplant(SLKT) in transplant candidates. Many treatment options including albumin, vasoconstrictors, renal replacement therapy, and eventual LT have remained a mainstay in the treatment of HRS. Unfortunately, even after aggressive measures such as terlipressin use, the rate of recovery is less than 50% of patients. Moreover, current SLKT guidelines include:(1) estimation of glomerular filtration rate of 30 m L/min or less for 4-8 wk;(2) proteinuria > 2 g/d; or(3) biopsy proven interstitial fibrosis or glomerulosclerosis. Even with these updated criteria there is a lack of consistency regarding longterm benefits for SLKT vs LT alone. Finally, in regards to kidney dysfunction in the post-transplant setting, an estimation of glomerular filtration rate < 60 mL /min per 1.73 m2 may be associated with an increased risk of patients having long-term end stage renal disease. HRS is common in patients with cirrhosis and those on liver transplant waitlist. Prompt identification and therapy initiation in transplant candidates with HRS may improve post-transplantation outcomes. Future studies identifying optimal vasoconstrictor regimens, alternative therapies, and factors predictive of response to therapy are needed. The appropriate use of SLKT in patients with HRS remains controversial and requires further evidence by the transplant community. | Rohan M Modi Nishi Patel Sherif N Metwally Khalid Mumtaz | 2016 | World Journal of Hepatology2016，8，24： | 8 |
| 2 | Dynamics of a multimodule variable geometry manipulator显示文摘 | CARON M MODI V J MISRA A K | 2002 | Acta Astronautica2002，50，10： | 2 |
| 3 | Trends and outcomes of transarterial chemoembolization in hepatocellular carcinoma:a national survey显示文摘BACKGROUND:Transarterial chemoembolization(TACE) is a palliative procedure frequently used in patients with advanced hepatocellular carcinoma(HCC). We examined the national inpatient trends of TACE and related outcomes in the United States over the last decade.METHODS:We utilized the National Inpatient Sample(2002 to 2012) and performed trend analyses of TACE for HCC in all adult patients(age >18 years). Multivariate analyses for the outcomes of in-hospital 'procedure-related complications'(PRCs) and 'post-procedure complications'(PPCs) were performed. We also compared early(2002 to 2006) and late(2007 to 2012) eras by multivariate analyses to identify predictors of complications, healthcare resource utilization and mortality.RESULTS:Overall, 19058 patients underwent TACE for HCC where PRCs and PPCs were seen in 24.2% and 17.6% of patients, respectively. The overall trends in the use of TACE(P<0.001) and associated PRCs(P=0.006) were observed to be increasing. There was less mortality [adjusted Odds ratio(a OR):0.58; 95% CI:0.41, 0.82], reduced length of hospital stay(-1.87 days; 95% CI:-2.77,-0.97) and increased hospital charges($19232; 95% CI:11013, 27451) in the late era. Additionally, there was increased mortality(a OR:4.07; 95% CI:2.96, 5.59), PRCs(a OR:3.21; 95% CI:2.56, 4.02), and PPCs(a OR:2.70; 95% CI:2.11, 3.46) among patients with coagulopathy.CONCLUSIONS:There is an increasing trend of TACE utilization in HCC. However, the outcomes are worse in patients with coagulopathy. Although PRCs have increased, mortality has decreased in recent years. These findings should be considered during TACE evaluation in patients with HCC. | Khalid Mumtaz Nishi Patel Rohan M Modi Vihang Patel Alice Hinton James Hanje Sylvester M Black Somashaker Krishna | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，6： | 2 |
| 4 | Cold blood versus cold crystalloid cardioplegia for repair of ventricular septal defects in pediatric heart surgery: a randomized controlled trial 显示文摘 | Modi P Imura H | 2002 | Ann Thorac Surg2002，74，53： | 1 |
| 5 | Heparinoid active sulphated polysaccharides from marine algae as potential blood antico agulant agents 显示文摘 | Shanmugam M Mody K H | 2000 | Currem Science2000，79，16： | 1 |
| 6 | Real-time imaging of trapping and ureasedependent transmigration of Cryptococcus neoformans in mouse brain显示文摘 | Shi M Li SS Zheng C Jones GJ Kim KS Zhou H Kubes P Mody CH | 2010 | J Clin Invest2010，120，5： | 1 |
| 7 | A rabbit model for monitoring in vivo viability of human platelet concentrates using flow cytometry显示文摘 | Leytin V Allen DJ Mody M | 2002 | Transfusion2002，42，7： | 1 |
| 8 | Rosiglitazone sensitizes MDA-MB-231 breast cancer ceils to anti-tumour effects of turnout necrosis factor-alpha, CHll and CYC202显示文摘 | Mody M Dharker N Bloomston M | 2007 | Endocr Relat Cancer2007，14，2： | 1 |
| 9 | Improved glucose homeostasis in mice with muscle-specific deletion of protein-tyrosine phosphatase 1B显示文摘 | Delibegovic M Bence K K Mody N | 2007 | Mol Cell Biol2007，27，21： | 1 |
| 10 | Glucagon-like peptide-1 in- creases beta-cell glucose competence and proliferation by translational induction of insulin-like growth factor-1 receptor expression显示文摘 | Comu M Modi H Kawamori D | 2010 | J Bi- ol Chem2010，285，10： | 1 |
| 11 | Role of vinpocetine in cerebrovascular diseases显示文摘 | Patyar S Prakash A Modi M | | 0，，03： | 1 |
| 12 | Role of alloy matrix and dispersoid on corrosion behavior of cast aluminum alloy composites 显示文摘 | Modi O P Saxena M | 1998 | Corrosion1998，，2： | 1 |
| 13 | Urodynamic profile of dia- betic patients with lower urinary tract symptoms : association of dia- betic cystopathy with autonomic and peripheral neuropathy 显示文摘 | Bansal R Agarwal MM Modi M | 2011 | Urology2011，77，3： | 1 |
| 14 | Tachycardia induction with ventricular extrastimuli differentiates atypical atrioventricular nodal reentrant tachycardia from orthodromic reciprocating tachycar- dia显示文摘 | OBEYESEKERE M GULA L J MODI S | 2012 | Heart Rhythm2012，9，： | 1 |
| 15 | Analysis of crack propagation and crack growth in concrete by means of fracture mechanics and finite dements显示文摘 | HILLERBORG A MODI~ER M PETERSON P E | 1976 | Cement and Concrete Research1976，6，6： | 1 |
| 16 | Adrenal insufficiency in the critically ill neonate and child显示文摘 | Langer M Modi BP Agus M | 2006 | Curr Opin Pediatr2006，18，4： | 1 |
| 17 | How the subprime crisis went global: Evidence from bank credit default swap spreads显示文摘 | Eichengreen B Mody A Nedeljkovic M | 2012 | Journal of International Money and Finance2012，31，5： | 1 |
| 18 | GLUT1 expression in human breast carcinoma: correlation with known prognostic mark- ers 显示文摘 | Younes M Brown R W Mody D R | 1995 | Anticancer Res1995，15，6： | 1 |
| 19 | Imipenem resistance of Pseudomonas in pneumonia: a systematic Literature reterature review显示文摘 | Zilberg M D Chen J Mody S H | 2010 | BMC Pulm Med2010，26，10： | 1 |
| 20 | ADOPT: Asynchronous Distributed Constraint Optimization with Quality Guarantees显示文摘 | Modi P Shen W Tambe M | 2005 | Artificial Intelligence2005，161，： | 1 |
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