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| 1 | Preventing post-endoscopic retrograde cholangiopancreatography pancreatitis: What can be done?显示文摘Post-endoscopic retrograde cholangiopancreatographypancreatitis(PEP) is the most common complication of endoscopic retrograde cholangiopancreatography. The incidence of post-endoscopic retrograde cholangiopancreatography(ERCP) pancreatitis varies substantially and is reported around 1%-10%, although there are some reports with an incidence of around 30%. Usually, PEP is a mild or moderate pancreatitis, but in some instances it can be severe and fatal. Generally, it is defined as the onset of new pancreatictype abdominal pain severe enough to require hospital admission or prolonged hospital stay with levels of serum amylase two to three times greater than normal, occurring 24 h after ERCP. Several methods have been adopted for preventing pancreatitis, such as pharmacological or endoscopic approaches. Regarding medical prevention, only non-steroidal anti-inflammatory drugs, namely diclofenac sodium and indomethacin, are recommended, but there are some other drugs which have some potential benefits in reducing the incidence of post-ERCP pancreatitis. Endoscopic preventive measures include cannulation(wire guided) and pancreatic stenting, while the adoption of the early pre-cut technique is still arguable. This review will attempt to present and discuss different ways of preventing post-ERCP pancreatitis. | Goran Hauser Marko Milosevic Davor Stimac Enver Zerem Predrag Jovanovi? Ivana Blazevic | 2015 | World Journal of Gastroenterology2015，21，4： | 22 |
| 2 | Laparoscopic 肝切除术: 当前的角色和限制显示文摘 Laparoscopic liver resection (LLR) for the treatment of benign and malignant liver lesions is often performed at specialized centers. Technological advances, such as laparoscopic ultrasonography and electrosurgical tools, have afforded surgeons simultaneous improvements in surgical technique. The utilization of minimally invasive techniques for liver resection has been reported to reduce operative time, decrease blood loss, and shorten length of hospital stay with equivalent postoperative mortality and morbidity rates compared to open liver resection (OLR). Non-anatomic liver resection and left lateral sectionectomy are now routinely performed laparoscopically at many institutions. Furthermore, major hepatic resections are performed by pure laparoscopy, hand-assisted technique, and the hybrid method. In addition, robotic surgery and single port surgery are revealing early promising results. The consensus recommendation for the treatment of benign liver disease and malignant lesions remains unchanged when considering a laparoscopic approach, except when comorbidities and anatomic limitations of the liver lesion preclude this technique. Disease free and survival rates after LLR for hepatocellular carcinoma and metastatic colon cancer correspond to OLR. Patient selection is a significant factor for these favorable outcomes. The limitations include LLR of superior and posterior liver lesions; however, adjustments in technique may now consider a laparoscopic approach as a viable option. As growing data continue to reveal the feasibility and efficacy of laparoscopic liver surgery, this skill is increasingly being adopted by hepatobiliary surgeons. Although the full scope of laparoscopic liver surgery remains infrequently used by many general surgeons, this technique will become a standard in the treatment of liver diseases as studies continue to show favorable outcomes. | Rouzbeh Mostaedi Zoran Milosevic Ho-Seong Han Vijay P Khatri | 2012 | World Journal of Gastrointestinal Oncology2012，4，8： | 8 |
| 3 | Problems in screening colorectal cancer in the elderly显示文摘AIM: To explore the problems in the screening of colorectal carcinoma in the elderly.METHODS: Three models of colorectal cancer prevention were examined: standard screening, active check-up of suspected cases and summons to have endoscopic checkup for previously diagnosed colorectal polyps. The study was performed among three groups of elderly individuals:Group 1 (167 cases), hospitalized asymptomatic individuals without symptoms in large intestines. Group 2 (612 cases):old individuals at home for the aged, out of which 32 showed symptoms of colon disorders; Group 3 (44 cases): elderly people with diagnosed polyps. As a result of 1788rectosigmoidoscopies, we identified 61 individuals with polyps, out of which 44 patients were over 65 years old.However, only 9 of these 44 individuals agreed to have the endoscopy performed again.RESULTS: One cancer and 13 polyps were detected in Group 1, and two polyps in Group 2. However, it should be noted that only eleven individuals from Group 2 agreed to have the endoscopy. In Group 3, there were no relapses of the polyps among the nine individuals who came back for the endoscopy.CONCLUSION: Poor understanding of the screening procedures is one of the greatest problems in early detection of the cancer in the aged. Paradoxically, the cooperation is better with hospitalized patients, than with 'successfully old'persons. | DavidoviM.Mladen Milosevic P.Dragoslav Zdravkovic Sanja Bojic Bozidar Djurica Snezana | 2003 | World Journal of Gastroenterology2003，9，10： | 4 |
| 4 | Subchronic Oral Cadmium Exposure Exerts both Stimulatory and Suppressive Effects on Pulmonary Inflammation/Immune Reactivity in Rats显示文摘Objective The aim of this study is to investigate the effects of oral cadmium(Cd) ingestion on the pulmonary immune response. Methods Determination of Cd content in lungs and histopathological evaluation of the tissue was performed in rats following 30-day oral Cd administration(5 and 50 mg/L). Antioxidant enzyme defense(superoxide dismutase and catalase), cell infiltration, and production of tumor necrosis factor(TNF) and interferon(IFN)-γ, as well as the activity of myeloperoxidase(MPO), nitric oxide(NO), and various cytokines [interleukin(IL)-1β, IL-6, IL-10, and IL-17] were investigated. Results Cd caused tissue damage and cell infiltration in the lungs, and this damage was more pronounced at higher doses. Cd deposition resulted in lung inflammation characterized by a dose-dependent IL-1β increase in lung homogenates, increased TNF levels at both doses, and IL-6 stimulation at low doses with inhibition observed at higher doses. Cd exerted differential effects on lung leukocytes isolated by enzyme digestion, and these effects were characterized by a lack of change in the production of reactive oxygen and nitrogen species, an inhibition of IL-1β and TNF, and stimulation of MPO and IFN-γ. The higher capacity of Cd-exposed lung cells to respond to the opportunistic pathogen Staphylococcus epidermidis was demonstrated in vitro. Conclusion The potential of ingested Cd to exert both proinflammatory and immunosuppressive effects on pulmonary tissue inflammation and immune reactivity highlights the complex immunomodulatory actions of this metal. | KULAS Jelena NINKOV Marina TUCOVIC Dina POPOV Aleksandrov Aleksandra UKROPINA Mirela CAKIC MILOSEVIC Maja MUTIC Jelena KATARANOVSKI Milena MIKROV Ivana | 2019 | Biomedical and Environmental Sciences2019，32，7： | 4 |
| 5 | Diffusion-weighted MRI in cervical cancer显示文摘 | Patrick Z. McVeigh Aejaz M. Syed Michael Milosevic Anthony Fyles Masoom A. Haider | 2008 | European Radiology2008，，5： | 3 |
| 6 | Splenectomy with chemotherapy vs surgery alone as initial treatment for splenic marginal zone lymphoma显示文摘AIM:To evaluate the clinical characteristics of splenic marginal-zone lymphoma (SMZL) following antigen expression and the influence of therapeutic approaches on clinical outcome and overall survival (OS).METHODS: A total of 30 patients with typical histological and immunohistochemical SMZL patterns were examined. Splenectomy plus chemotherapy was applied in 20 patients, while splenectomy as a single treatment-option was performed in 10 patients. Prognostic factor and overall survival rate were analyzed.RESULTS: Complete remission (CR) was achieved in 20 (66.7%), partial remission (PR) in seven (23.3%), and lethal outcome due to disease progression occurred in three (10.0%) patients. Median survival of patients with a splenectomy was 93.0 mo and for patients with splenectomy plus chemotherapy it was 107.5 mo (Log rank=0.056, P>0.05). Time from onset of first symptoms to the beginning of the treatment (mean 9.4 mo) was influenced by spleen dimensions, as measured by computerized tomography and ultra-sound (t=2.558, P=0.018). Strong positivity (+++) of CD20 antigen expression in splenic tissue had a positive influence on OS (Log rank=5.244, P<0.05). The analysis of factors interfering with survival (by the Kaplan-Meier method) revealed that gender, general symptoms, clinical stage, and spleen infiltration type (nodular vs diffuse) had no significant (P>0.05) effects on the OS. The expression of other antigens (immunohistochemistry) also had no effect on survival-rate, as measured by a χ2 test (P>0.05).CONCLUSION: Initial splenectomy combined with chemotherapy has been shown to be beneficial due to its advanced remission rate/duration; however, a larger controlled clinical study is required to conf irm our findings. | Rajko Milosevic Milena Todorovic Bela Balint Miodrag Jevtic Miodrag Krstic Elizabeta Ristanovic Nebojsa Antonijevic Mirjana Pavlovic Maja Perunicic Milan Petrovic Biljana Mihaljevic | 2009 | World Journal of Gastroenterology2009，15，32： | 2 |
| 7 | Vohage stability protection and control using a wide-area network of phasor measurements 显示文摘 | MILOSEVIC B BEGOVIC M | 2003 | IEEE Transactions on Power Systems2003，15，1： | 1 |
| 8 | Tumor hypoxia has independent predictor impact only in patients with node-negative cervix cancer显示文摘 | Fyles A Milosevic M Hedley D | 2002 | J Clin Oncol2002，20，3： | 1 |
| 9 | Voltage-stability protection and control using a wide-area network of phasor measurements 显示文摘 | Milosevic Borka Begovic Miroslav | 2003 | IEEE Trans on Power Systems2003，18，1： | 1 |
| 10 | Effects of the vascular disrupting agent ZD6126 on interstitial fluid pressure and cell survival in tumors 显示文摘 | Skliarenko JV Lunt S J Gordon ML Vitkin A Milosevic M Hill RP | 2006 | Cancer Res2006，66，4： | 1 |
| 11 | The DNA damageinduced decrease of Bcl-2 is secondary to the activation of apoptotic effector caspases显示文摘 | Milosevic J Hoffarth S Huber C | | 0，，44： | 1 |
| 12 | Orbital and ocular adnexal mucosa-associated lymphoid tissue(MALT)lymphoma:a single-center 10-year experience显示文摘 | Smiljanic M Milosevic R Antic D | 2013 | Med Oncol2013，30，4： | 1 |
| 13 | Rapid formation of high T-C phase in Bi-Pb-Sr(-∈)Ca-Cu-O system显示文摘 | Mancic L Milosevic O Rizzo F | 2000 | Physica C2000，，： | 1 |
| 14 | Fractal and nonfractal properties of triadic Koch curve 显示文摘 | Milosevic Nebojsa T Ristanovic Dusan | 2007 | Chaos Solitons and Fractals2007，34，4： | 1 |
| 15 | Polarographic electrode study of tumor oxygenation in clinically localized prostate cancer显示文摘 | Parker C Milosevic M Toi A | 2004 | Int J Radiat Oncol Biol Phys2004，58，3： | 1 |
| 16 | Rheological behaviour of thixotropic starch显示文摘 | DJAKOVIC L J SOVILJI V MILOSEVIC S | 1990 | Starch/Starke1990，42，： | 1 |
| 17 | Frequent deletions of JARID2 in leukemic transformation of chronic myeloid malignancies显示文摘 | Puda A Milosevic JD Berg T | 2012 | Am J Hematol2012，87，3： | 1 |
| 18 | A Rare Root Canal Configuration of Maxillary Second Molar: A Case Report显示文摘 | Gautam P. Badole Rakesh N. Bahadure M. M. Warhadpande Rajesh Kubde N. Brezniak A. Milosevic E. F. Wright | 2012 | Case Reports in Dentistry2012，，： | 1 |
| 19 | high TC superconducting powders synthesis from aerosol显示文摘 | Mancic L Milosevic O Ristic M M | 2001 | Journal of the European Ceramic Society2001，21，： | 1 |
| 20 | Gas-solid and gas-liquid mass transfer coefficients显示文摘 | Dudukovic A Milosevic V Pjandvic R | 1996 | AICHE J1996，42，： | 1 |
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