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| 1 | Placental accommodations for transport and metabolism during intra-uterine crowding in pigs显示文摘Litter size and birth weights are limited by uterine capacity, defined as the ability of the uterus to maintain the appropriate development of some number of conceptuses. Uterine capacity is the result of the combined effects of uterine, placental and embryo/fetal function. The number of living conceptuses that the uterus is capable of supporting is greater during early gestation compared to later gestation. Plots of log fetal weight versus log placental weight also indicate that fetal weights are less sensitive to reduced placental weight(and therefore reduced intrauterine space) in early gestation compared to late gestation. However, even in late gestation,mechanisms still exist that maintain fetal growth when the size of the placenta is reduced. One such mechanism is likely to be improved development of the folded placental-epithelial/maternal-epithelial bilayer. Fold depth, and therefore the maternal fetal interactive surface, increases as gestation advances and is greater in placenta from small fetuses. On the fetal side of the placenta, the epithelial bilayer is embedded in stromal tissue. Glycosaminoglycans are major components of stroma, including hyaluronan and heparan sulfate. Hyaluronidases and heparanases are present within placental tissues, and likely play roles in modification of stromal components to facilitate fold development. Glycosaminoglycans are polymers of forms of glucose(glucosamine, glucuronic acid, iduronic acid)suggesting that glycosaminoglycan synthesis may compete with the glucose needs of the developing fetus.Pig conceptuses are fructogenic, such that a substantial portion of glucose transferred from mother to fetus is converted to fructose. Fructose is an intermediate product in the synthesis of glucosamine from glucose, and glucosamine is linked to regulation of trophoblast cell proliferation through regulation of m TOR. These findings suggest a link between glucose, fructose, glucosamine synthesis, GAG production, and placental morphogenesis,but the details of these interactions remain unclear. In addition, recent placental epithelial transcriptome analysis identified several glucose, amino acid, lipid, vitamin, mineral and hormone transporter mechanisms within the placenta. Further elucidation of mechanisms of placental morphogenesis and solute transport could provide clues to improving nutrient transport to the pig fetus, potentially increasing litter size and piglet birth weights. | Jeffrey L Vallet Anthony K Mc Neel Jeremy R Miles Bradley A Freking | 2015 | Journal of Animal Science and Biotechnology2015，6，2： | 5 |
| 2 | Designing Strategic Human Resources Systems 显示文摘 | Miles R E Snow C C | 1984 | Organisational Dynamics1984，，： | 1 |
| 3 | Examination of swirling flow using electrical resistance tomography 显示文摘 | STEVENSONA R HARRISON T L MILES N | 2006 | Powder Technology2006，162，2： | 1 |
| 4 | Uric acid excretion by the chickens as an indicator of dietary protein quality显示文摘 | Miles R D Featherston W R | 1976 | Poultry Sci1976，55，： | 1 |
| 5 | ARI-1: b-lactamase-mediated imipenem resistance in Acinetobacter baumannii显示文摘 | Paton R Miles R S Hood J | 1993 | Int J Antimicrob Agents1993，2，： | 1 |
| 6 | Combustion-properties of biomass 显示文摘 | Jenkins B M Baxter L L Miles T R | 1998 | Fuel Processing Technology1998，54，： | 1 |
| 7 | Failure of femoral head fixation:a cadaveric analysis of lag screw cut-out with the gamma locking nail and AO dynamic hip screw显示文摘 | Haynes R C Poll R G Miles A W | | 0，，5： | 1 |
| 8 | The effect of a vibration appliance on movement and patient discomfort:a prospective randomized clini- cal trial显示文摘 | Miles P Smith H Weyant R | 2012 | Aust Orthod J2012，28，2： | 1 |
| 9 | Antibiotic prophy- laxis in the initial management of severe acute pancreations显示文摘 | POWELL J J MILES R SIRIWARDENA AK | | Br J Surg0，85，5： | 1 |
| 10 | HPLC analysis of reduced and oxidized coenzyme QlO in plasma by a single dilution step 显示文摘 | TANG H R MILES V M DEGRAUW A | 2001 | Clin Chern2001，47，： | 1 |
| 11 | Mechanically Coupled Ears for Directional Hearing in the Parasitoid fly Ormia Ochracea显示文摘 | MILES R N ROBERT D HOY R R | 1995 | Journal of the Acoustical Society of America1995，98，6： | 1 |
| 12 | Thedirect release of nitric oxide by Gypenoside derived from theHerb Gynostemma pentaphyllum显示文摘 | Miles A Tanner Xin Bu J Alan Steimle P R Myers | 1999 | Biology and Chemis-try1999，3，5： | 1 |
| 13 | The effect of dietary supplemention with copper sulfate or tribasic chloride copper chloride on broiler performance,relative copper bioavailability,and dierary prooxidant activity显示文摘 | Miles R D O'Keefe S F Henry P R | 1998 | Poultry Science1998，77，3： | 1 |
| 14 | Soil phosphorus fractions after 111 years of animal manure and fertilizer applications 显示文摘 | Motavalli P P Miles R J | 2002 | Biol Fertil Soils2002，311，： | 1 |
| 15 | Perfusion C T: a worthwhile enhance- ment 显示文摘 | Miles K A Griffiths M R | 2003 | Br J Radio12003，76，904： | 1 |
| 16 | Predictors and outcomes of fungal peritonitis in peritoneal dialysis patients显示文摘 | Miles R Hawley CM McDonald SP | 2009 | Kidney Int2009，76，： | 1 |
| 17 | Perfusion CT: a worthwhile enhancement显示文摘 | Miles K A Griffiths M R | 2003 | Br J Radiol2003，76，2： | 1 |
| 18 | Nonlinear optimization of well production considering gas lift and phase behavior显示文摘 | Miles R Palike Roland N Home | 1997 | SPE374281997，，： | 1 |
| 19 | A Meta-Analytic Test of the ImaginedContact Hypothesis显示文摘 | Miles E Crisp R J | 2013 | Group Processes & Intergroup Rela-tions2013，，1： | 1 |
| 20 | Combi- nation slralegy targeling VEGF and HGF/e-met in human renal cell carcinoma models显示文摘 | CIAMPORCERO E MILES K M ADELAIYE R | 2015 | Mol Cancer Ther2015，14，1： | 1 |
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