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| 1 | Dual color optogenetic control of neural populations using low-noise,multishank optoelectrodes显示文摘Optogenetics allows for optical manipulation of neuronal activity and has been increasingly combined with intracellular and extracellular electrophysiological recordings.Genetically-identified classes of neurons are optically manipulated,though the versatility of optogenetics would be increased if independent control of distinct neural populations could be achieved on a sufficient spatial and temporal resolution.We report a scalable multisite optoelectrode design that allows simultaneous optogenetic control of two spatially intermingled neuronal populations in vivo.We describe the design,fabrication,and assembly of low-noise,multisite/multicolor optoelectrodes.Each shank of the four-shank assembly is monolithically integrated with 8 recording sites and a dualcolor waveguide mixer with a 7×30μm cross-section,coupled to 405 nm and 635 nm injection laser diodes(ILDs)via gradient-index(GRIN)lenses to meet optical and thermal design requirements.To better understand noise on the recording channels generated during diode-based activation,we developed a lumped-circuit modeling approach for EMI coupling mechanisms and used it to limit artifacts to amplitudes under 100μV upto an optical output power of 450μW.We implanted the packaged devices into the CA1 pyramidal layer of awake mice,expressing Channelrhodopsin-2 in pyramidal cells and ChrimsonR in paravalbumin-expressing interneurons,and achieved optical excitation of each cell type using sub-mW illumination.We highlight the potential use of this technology for functional dissection of neural circuits. | Komal Kampasi Daniel F.English John Seymour Eran Stark Sam McKenzie Mihály Vöröslakos György Buzsáki Kensall D.Wise Euisik Yoon | 2018 | Microsystems & Nanoengineering2018，4，1： | 8 |
| 2 | New serological markers in pediatric patients with inflammatory bowel disease显示文摘The spectrum of serological markers associated with inflammatory bowel disease(IBD)is rapidly growing.Due to frequently delayed or missed diagnoses,the application of non-invasive diagnostic tests for IBD,as well as differentiation between ulcerative colitis(UC)and Crohn’s disease(CD),would be useful in the pediatric population.In addition,the combination of pancreatic autoantibodies and antibodies against Saccharomyces cerevisiae antibodies/perinuclear cytoplasmic antibody(pANCA)improved the sensitivity of serological markers in pediatric patients with CD and UC.Some studies suggested that age-associated differences in the patterns of antibodies may be present,particularly in the youngest children.In CD,most patients develop stricturing or perforating complications,and a significant numberof patients undergo surgery during the disease course.Based on recent knowledge,serum antibodies are qualitatively and quantitatively associated with complicated CD behavior and CD-related surgery.Pediatric UC is characterized by extensive colitis and a high rate of colectomy.In patients with UC,high levels of antiCBir1 and pANCA are associated with the development of pouchitis after ileal pouch-anal anastomosis.Thus,serologic markers for IBD can be applied to stratify IBD patients into more homogeneous subgroups with respect to disease progression.In conclusion,identification of patients at an increased risk of rapid disease progression is of great interest,as the application of early and more aggressive pharmaceutical intervention could have the potential to alter the natural history of IBD,and reduce complications and hospitalizations. | Márta Kovács Katalin Eszter Müller Mária Papp Péter László Lakatos Mihály Cs?ndes Gábor Veres | 2014 | World Journal of Gastroenterology2014，20，17： | 4 |
| 3 | Comparative screening for thyroid disorders in old age in areas of iodine deficiency, long‐term iodine prophylaxis and abundant iodine intake显示文摘 | IstvánSzabolcs JanPodoba JoachimFeldkamp OrsolyaDohán IldikóFarkas MihálynéSajgó Krisztina I.Takáts MiklósGóth LászlóKovács KatalinKressinszky PeterHnilica GézaSzilágyi | 2003 | Clinical Endocrinology2003，，1： | 2 |
| 4 | Soot combustion and NOx adsorption on Co, Ba, K/ZrO2 显示文摘 | Mih V G Banu's E D Ulla M A | 2008 | Catalysis Today2008，，： | 1 |
| 5 | 查看详情显示文摘 | László P Juan F G R Péter F Attila G Mihály D László A Bienvenida G Antonio M | | 0，，03： | 1 |
| 6 | Thermal analysis of K (x)/La2O3, active catalysts for the abatement of diesel exhaust contaminants 显示文摘 | Mih V G Querini C A Miro E E | 2003 | Thermochimica Acta2003，404，12： | 1 |
| 7 | Simultaneous removal of soot and nitrogen oxides from diesel engine exhausts显示文摘 | Pisarello M L Mih V Peralta M A | 2002 | Catalysis Today2002，75，14： | 1 |
| 8 | Effects of L-carnitine supplementation of diets differing in energy levels on performance,abdominal fat content,and yield and composition of edible meat of broilers显示文摘 | RABIE M H MIH(A)LY SZIL(A)GYI | 1998 | British Journal of Nutrition1998，80，： | 1 |
| 9 | Central corneal volume and endothelial cell count following femtosecond laser-assisted refractive cataract surgery compared to conventional phacoemulsification显示文摘 | Takács AI Kovács I Miháltz K | 2012 | J Refract Surg2012，28，6： | 1 |
| 10 | Abatement of diesel-exhaust pollutants: NOx storage and soot combustion on K/La2O3 catalysts 显示文摘 | Mih V G Pissarello M L Miro E E | 2003 | Applied Catalysis B: Environmental2003，41，4： | 1 |
| 11 | Velocity of air-core vortices at hydraulic intakes显示文摘 | Hite J E Mih W C | 1994 | Journal of Hydraulic Engineering ASCE1994，120，3： | 1 |
| 12 | Gustatory perception alterations in obesity: An fMRI study显示文摘 | Csaba Szalay Mihály Aradi Attila Schwarcz Gergely Orsi Gábor Perlaki Lívia Németh Sophia Hanna Gábor Takács István Szabó László Bajnok András Vereczkei Tamás Dóczi József Janszky Sámuel Komoly Péter ?rs Horváth László Lénárd Zoltán Karadi | 2012 | Brain Research2012，，： | 1 |
| 13 | NOx trapping and soot combustion on BaCoO3-y pemvskite:LRS and FFIR characterization显示文摘 | Mih V G Ulla M A Mira E E | 2005 | Applied Catalysis B : Environmental2005，57，1： | 1 |
| 14 | Mechanism of nitrite oxidation and oxidoreductase systems in Nitrobacter agilis显示文摘 | Sewell DL | 1981 | Curr Microbiol1981，，5： | 1 |
| 15 | Classification of Coronary Atherosclerotic Plaques Ex Vivo With T1, T2, and Ultrashort Echo Time CMR显示文摘 | Mihály Károlyi Harald Seifarth Gary Liew Christopher L. Schlett Pál Maurovich-Horvat Paul Stolzmann Guangping Dai Shuning Huang Craig J. Goergen Masataka Nakano Fumiyuki Otsuka Renu Virmani Udo Hoffmann David E. Sosnovik | 2013 | JACC: Cardiovascular Imaging2013，，4： | 1 |
| 16 | Soot combustion and NOx adsorption on Co, Ba, K/ZrO2 显示文摘 | Mih V G Banus E D Ulla M A | 2008 | Catalysis Today2008，，： | 1 |
| 17 | Nature and Climate Effects of Individual Tropospheric Aerosol Particles显示文摘 | Mihály Pósfai Peter R. Buseck | 2010 | Annual Review of Earth and Planetary Sciences2010，，： | 1 |
| 18 | Diazoxide and dimethyl sulphoxide prevent cerebral hypoperfusion-related learning dysfunction and brain damage after carotid artery occlusion显示文摘 | Eszter Farkas ádám Institóris Ferenc Domoki András Mihály Paul G.M Luiten Ferenc Bari | 2004 | Brain Research2004，，2： | 1 |
| 19 | Congenital radial head dislocations 显示文摘 | Sachar K Mih AD | 1998 | Hand Clin1998，14，1： | 1 |
| 20 | The debrecen stroke database: demographic characteristics, risk factors, stroke severity and outcome in 8088 consecutive hospitalised patients with acute cerebrovascular disease 显示文摘 | Bereczki D Mih a lka L Fekete I | 2009 | Int J Stroke2009，4，5： | 1 |
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