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15篇 您的检索式：作者名="MATTHEW CG"

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		题名	作者	年代	出处	被引量
	1	Chemoprotective effects of curcumin in esophageal epithelial cells exposed to bile acids显示文摘AIM:To investigate the ability of curcumin to counteract the impact of bile acids on gene expression of esophageal epithelial cells.METHODS:An esophageal epithelial cell line(HET1A)was treated with curcumin in the presence of deoxycholic acid.Cell proliferation and viability assays were used to establish an appropriate dose range for curcumin.The combined and individual effects of curcumin and bile acid on cyclooxygenase-2(COX-2)and superoxide dismutase(SOD-1 and SOD-2)gene expression were also assessed.RESULTS:Curcumin in a dose range of 10-100μmol/L displayed minimal inhibition of HET-1A cell viability.Deoxycholic acid at a concentration of 200μmol/L caused a 2.4-fold increase in COX-2 gene expression compared to vehicle control.The increased expression of COX-2 induced by deoxycholic acid was partially reversed by the addition of curcumin,and curcumin reduced COX-2 expression 3.3-to 1.3-fold.HET-1A cells exposed to bile acid yielded reduced expression of SOD-1 and SOD-2 genes with the exception that high dose deoxycholic acid at 200μmol/L led to a 3-fold increase in SOD-2 expression.The addition of curcumin treatment partially reversed the bile acid-induced reduction in SOD-1 expression at all concentrations of curcumin tested.CONCLUSION:Curcumin reverses bile acid suppression of gene expression of SOD-1.Curcumin is also able to inhibit bile acid induction of COX-2 gene expression.	Matthew R Bower Harini S Aiyer Robert CG Martin Yan Li	2010	World Journal of Gastroenterology2010，16，33：	10
	2	On the meaning of the WISC-R third factor: relations to selected neuropsyehological measures 显示文摘	Ownby RL Matthews CG	1995	J Consulting Clin Psychol1995，53，4：	1
	3	The role of hypothermia in the management of severe brain injury显示文摘	HARRIS OA GOLFORD MC MATTHEW CG	2010	Arch Neurol2010，59，：	1
	4	Staphylococcus lugdunensis endocarditis following cardiac catheterisation显示文摘	Matthews PC Missouris CG Jordaan J	2008	Int J Cardiol2008，130，1：	1
	5	On the meaning of the WISC-R third factor:relations to selects neuropsychological measures显示文摘	Ownby RL Matthews CG	1995	J Consulting Clin Psychol1995，53，：	1
	6	3-ehloropropane-l,2-diol (3-MCPD) in food ingredients from UK food producers and ingredient suppliers显示文摘	Hamlet CG Jayaratne SM Matthews W	2002	Food Addit and Contam2002，19，1：	1
	7	3-Monochloropropane-1, 2-diol (3-MCPD) in food ingredients from UK food producers and ingredient suppliers 显示文摘	Hamlet CG Jayaratne SM Matthews W	2002	Food Addit Contam2002，19，1：	1
	8	Improved patient survival using a modified resuscitation protocol for out-of-hospital cardiac arrest显示文摘	Alex GG Matthew CG Joseph AS	2009	Circulation2009，119，：	1
	9	La Crosse and other forms of California encephalitis显示文摘	Rust RS Thompson WH Matthews CG	1999	JChild Neurology1999，14，1：	1
	10	Sympathetic re- activity to acute stress and immune response in women显示文摘	Matthews KA Caggiula AR Mcallister CG	1995	Psycho- som Med1995，57，6：	1
	11	The role of hypot-hermia in the management of severe brain jnjury显示文摘	Harris OA Golford MC Matthew CG		0，，：	1
	12	Serum cortisol and 17hydroxyprogesterone interrelation in classic 21-hydroxylase deficiency: is current replacement therapy satisfactory?显示文摘	Channandari E Matthews DR Johnston A Brook CG Hindmarsh PC	2001	J Clin Endocrinol Metab2001，86，10：	1
	13	The role of hypot- hermia in the management of severe brain jnjury显示文摘	Harris OA Golford MC Matthew CG	2002	Arch - Neu- roh2002，59，：	1
	14	Sympathetic reactivity to acute stress and immune response in women 显示文摘	Matthews KA Caggiula AR McAllister CG	1995	Psychosom Med1995，57，6：	1
	15	Effect of major motor seizure frequency upon cognitive-intellectual functions in adults显示文摘	Matthews CG	1977	Epilepsia1977，18，：	1

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