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1Is there a real diagnostic impact of elastosonography and contrast-enhanced ultrasonography in the management of thyroid nodules?显示文摘Ultrasonography(US) and the new applications US elastography(USE) and contrast-enhanced US(CEUS) are used in the screening of thyroid nodules,for which fine-needle aspiration biopsy(FNAB) is the best single diagnostic test.The aim of the study was to compare the sensitivity,specificity,positive predictive value(PPV),and accuracy of the four examinations in nodules with cytological and histological diagnoses.The study used data from US,FNAB,USE(elasticity(ELX 2/1) index),and CEUS(Peak index and time to peak(TTP) index) evaluated in 73 thyroid nodules in 63 consecutive patients likely to undergo surgery.Cytological-histological correlation was available for 38 nodules.No correlation emerged between nodule size and cytological results.A significant(P=0.03) positive correlation between cumulative US findings and cytological results was found.In addition,significant correlations between cumulative US findings and cytology(P=0.02) and between cumulative US findings and histology(P<0.0001) were found.US showed the best specificity and PPV,and FNAB the best sensitivity.There was no significant difference in the ELX 2/1 index,Peak index,or TTP index among nodules subdivided according to cytological scores.No significant correlation was found between ELX 2/1 index,Peak index,and TTP index,on the one hand,and nodule size,US cumulative findings,cytology,and histology on the other hand.The sensitivity of the ELX 2/1 index was high,but its specificity was very low.The accuracy and PPV of USE were lower than those of the other procedures.Only the correlation between Peak index and cumulative US findings reached a value close to significance.Our ultimate aim is to minimise unnecessary thyroidectomy.US and FNAB continue to play a central diagnostic role.The use of a US score showed high specificity and PPV.The specificity of FNAB was low in this selected series because of the numbers of indeterminate cytological responses.USE and CEUS are innovative techniques that need to be standardized.The ELX 2/1 index,Peak index,and TTP index seem to be unrelated to histology.The best statistical data on USE and CEUS concerned their sensitivity and PPV,respectively.At present,USE and CEUS are too time-consuming and of limited utility in selecting patients for surgery.Massimo GIUSTI Davide ORLANDI Giulia MELLE Barbara MASSA Enzo SILVESTRI Francesco MINUTO Gianni TURTULICI 2013Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2013,14,3:17
2Rapid mitogen-activated protein kinase activation by transforming growth factor α in wounded rat intestinal epithelial cells显示文摘RapidmitogenactivatedproteinkinaseactivationbytransforminggrowthfactorαinwoundedratintestinalepithelialcelsMichaelGkee,Michi...Michael Gke, Michiyuki Kanai, Kathryn Lynch Devaney, and Daniel K. Podolsky Gastrointestinal Unit, Department of Medicine, and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital and Harvard Medical School, Boston, Massa 1998World Journal of Gastroenterology1998,4,3:14
3博物馆最佳环境条件显示文摘在对博物馆文物保护问题专家所提供的数据、资料进行广泛的最新研究的基础上,我们得以勾勒出一幅每件文物最佳保存所涉及的主要环境参数的简明图示。它表明了“文物安全保存范围”。应该强调指出,在考虑文物材质长期暴露于其中并逐渐适应的环境压力(对每个环境因素,每件文物所承受的环境压力都不一样)对文物的影响程度时,还应该考虑文物的“历史年龄”。由于目前还不可能建立一套可靠的标准,本文对上述论及的方面进行了必要的探讨,并对文献中的有时甚至是矛盾的数据进行了较深入地论证。Cavallini T. Massa S. Russo A. 马涛 2001文物保护与考古科学2001,13,1:4
4Enhanced recovery after surgery in liver transplantation:Challenges and feasibility显示文摘BACKGROUND Enhanced recovery after surgery(ERAS)started a revolution that changed age-old surgical stereotypical practices regarding the overall management of the surgical patient.In the last decade,ERAS has gained significant acceptance in the community of general surgery,in addition to several other surgical specialties,as the evidence of its advantages continues to grow.One of the last remaining fields,given its significant complexity and intricate nature,is liver transplantation(LT).AIM To investigate the existing efforts at implementing ERAS in LT.METHODS We conducted a systematic review of the existing studies that evaluate ERAS in orthotopic LT,with a multimodal approach and focusing on measurable clinical primary endpoints,namely length of hospital stay.RESULTS All studies demonstrated a considerable decrease in length of hospital stay,with no readmission or negative impact of the ERAS protocol applied to the postoperative course.CONCLUSIONS ERAS is a well-validated multimodal approach for almost all types of surgical procedures,and its future in selected LT patients seems promising,as the preliminary results advocate for the safety and efficacy of ERAS in the field of LT.Georgios Katsanos Konstantina-Eleni Karakasi Nikolaos Antoniadis Stella Vasileiadou Athanasios Kofinas Antonios Morsi-Yeroyannis Evangelia Michailidou Ioannis Goulis Emmanouil Sinakos Olga Giouleme Ilias Marios Oikonomou George Evlavis Georgios Tsakiris Eleni Massa Eleni Mouloudi Georgios Tsoulfas 2022World Journal of Transplantation2022,12,7:3
5Severe cyclophosphamide-related hyponatremia in a patient with acute glomerulonephritis显示文摘Cyclophosphamide is frequently used to treat cancer,autoimmune and renal diseases,such as rapidly progressive glomerulonephritis.Its side effects are well-known,including bone marrow depression,infections,alopecia,sterility,bladder malignancy and hemorrhagic cystitis.Moreover,in some cases cyclophosphamide use has been related to the onset of hyponatremia,by development of a syndrome of inappropriate antidiuresis.Indeed,severe hyponatremia has been previously reported in patients treated with high-dose or moderate-dose of intravenous cyclophosphamide,while only few cases have been reported in patients treated with low dose.Here,we discuss a case of a syndrome of inappropriate antidiuresis followed to a single low-dose of intravenous cyclophosphamide in a patient with a histological diagnosis of acute glomerulonephritis,presenting as acute kidney injury.After cyclophosphamide administration(500 mg IV),while renal function gradually improved,the patient developed confusion and headache.Laboratory examinations showed serum sodium concentration dropped to 122 mmol per liter associated with an elevated urinary osmolality of 199 mO sm/kg,while common causes of acute hyponatremia were excluded.He was successfully treated with water restriction and hypertonic saline solution infusion with the resolution of the electrolyte disorder.This case,together with the previous ones already reported,highlights that electrolyte profile should be strictly monitored in patients undergoing cyclophosphamide therapy in order to early recognize the potentially lifethreatening complications of acute water retention.Pasquale Esposito Maria Valentina Domenech Nicoletta Serpieri Marta Calatroni Ilaria Massa Alessandro Avella Edoardo La Porta Luca Estienne Elena Caramella Teresa Rampino 2017World Journal of Nephrology2017,6,4:2
6Antidiabetic and antioxidant effects of Annona muricata (Annonaceae), aqueous extract on streptozotocin-induced diabetic rats显示文摘Ngueguim Tsofack Florence Massa Zibi Benoit Kouamouo Jonas Tchuidjang Alexandra Dzeufiet Djomeni Paul Désiré Kamtchouing Pierre Dimo Théophile 2014Journal of Ethnopharmacology2014,,2:2
7Survival of Escherichia coli O157:H7 in yoghurt during preparation and storage at 4℃显示文摘MASSA S ALTIERI C QUARANTA V 1997Applied Microbiology1997,24,:1
8Catalytic wet peroxide oxidation of phenolic solutions over Fe2O3/CeO2 and WO3/CeO2 catalyst systems显示文摘Massa P Da nov A Cabello F M 2008Cared Comm2008,,9:1
9Grculating levels of interleukin-6,interleukin-8 and tumor necrosis factor-alpha in children with autoimmune hepatitis显示文摘Maggiore G De Benedetti F Massa M 1995J Pediatr Gastroenterol Nutr1995,20,:1
10Mycorrhiza induced differential response to a yellows disease in tomato 显示文摘Lingua G D'Agostino G Massa N 2002Mycor- rhiza2002,12,4:1
11Bayesian compressive sampling for pattern synthesis with maximally sparse non uniform linear arrays显示文摘Giacomo Oliveri Andrea Massa 0,,02:1
12Postmortem changes in quality indices of ice-stored flounder (paralichthys patagonieus ) 显示文摘Massa A E Palacios D L Paredi M E 2005Journal of Food Biochemistry2005,29,5:1
13The importance of lipid solubility in antioxidants and free radical generating systems for determining lipoprotein peroxidation显示文摘Massaeli H Sobrattee S Pierce G N 1999Free Radical Bio Med1999,26,1112:1
14Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans 显示文摘MAI A ROTILI D MASSA S 2007Bioorganic & Medicinal Chemistry Letters2007,17,:1
15The incidence of right upper-lobe collapse when comparing a right-sided double-lumen tube versus a modified left double-lumen tube for left-sided thoracic sttrgery显示文摘Campos JH Massa FC Kernstine KH 2000Anesth Analg2000,90,3:1
16Fracture resistance of teethrestored with two different post-and-core designs cemented with two different cements:An in vitro study PartI显示文摘Mezzomo E Massa F Libera SD 2003Quintessence Int2003,34,3:1
17Landan-Kleffner syndrome:sleep EEG characteristics at onset显示文摘Massa R de Saint-Martin A Hirsch E 2000Clin Neurophysiol2000,111,2:1
18Fundamental voice frequency and jitter in girls and boys measured with electroglottography:influence of age and height显示文摘Linders B Massa GG Boersma B 1995Int J Pediatr Otorhinolaryngol1995,33,:1
19Growth hormone(GH) secretion in patients with childhood-onset GH deficiency:Retesting after one year of therapy and at final height显示文摘Thomas M Massa G Maes M 2003Horm Res2003,59,1:1
20Global ischemia induces apoptosis-associated genes in hippocampus 显示文摘Honkaniemi J Massa S M Breckinridge M 1996Brain Res Mol Brain Res1996,42,:1
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