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2篇 您的检索式:作者名="M.Mohebbian"
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1Application of a simple calorimetric data analysis on the binding study of cyanide ions by Jack bean urease显示文摘Cyanide ion was studied as an effector of Jack bean urease(JBU) at 300 K in 30 mmol/LTris buffer,pH 7 by isothermal titration calorimetry(ITC).The simple novel model was used for CN^- + JBU interaction over the whole range of CN^- concentrations.The binding parameters recovered from the simple novel model were attributed to the cyanide ion interaction.It was found that cyanide ion acted as a noncooperative inhibitor of JBU,and there is a set of 12 identical and independent binding sites for CN^- ions.The...G.Rezaei Behbehani A.A.Saboury M.Mohebbian S.Ghammamy 2010Chinese Chemical Letters2010,21,4:1
2Thermodynamic study of CN^- ion inhibition of Jack bean urease using the extended solvation theory显示文摘Cyanide ion was studied as an inhibitor of Jack bean urease at 300 K in 30 mmol/L tris buffer,pH 7.The inhibition was investigated by isothermal titration calorimetry(ITC).The extended solvation model was used for CN^- + JBU interaction over the whole range of CN^- concentrations.The binding parameters recovered from the solvation model were attributed to the cyanide ion interaction.It was found that cyanide ion acted as a non-cooperative inhibitor of urease,and there is a set of 12±0.12 identical and independent binding sites for CN^- ions.The dissociation equilibrium constant is 749.99μmol/L.The molar enthalpy of binding is△H=-13.60kJ mol^(-1).G.Rezaei Behbehani A.A.Saboury M.Mohebbian S.Tahmasbi Sarvestani M.Poorheravi 2009Chinese Chemical Letters2009,20,11:0
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